1HV2
 
 | | SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE | | 分子名称: | ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR | | 著者 | Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H. | | 登録日 | 2001-01-05 | | 公開日 | 2001-09-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
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6CO2
 | | Structure of an engineered protein (NUDT16TI) in complex with 53BP1 Tudor domains | | 分子名称: | NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1 | | 著者 | Botuyan, M.V, Thompson, J.R, Cui, G, Mer, G. | | 登録日 | 2018-03-10 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
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1CUR
 | | REDUCED RUSTICYANIN, NMR | | 分子名称: | COPPER (II) ION, CU(I) RUSTICYANIN | | 著者 | Botuyan, M.V, Dyson, H.J. | | 登録日 | 1996-04-19 | | 公開日 | 1996-11-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential.
J.Mol.Biol., 263, 1996
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7LIN
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7LIP
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7LIO
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7LIQ
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2G3R
 | | Crystal Structure of 53BP1 tandem tudor domains at 1.2 A resolution | | 分子名称: | SULFATE ION, Tumor suppressor p53-binding protein 1 | | 著者 | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | | 登録日 | 2006-02-20 | | 公開日 | 2007-01-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair.
Cell(Cambridge,Mass.), 127, 2006
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5VF0
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5VWE
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8V9U
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6VE5
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3P8D
 | | Crystal structure of the second Tudor domain of human PHF20 (homodimer form) | | 分子名称: | Medulloblastoma antigen MU-MB-50.72 | | 著者 | Cui, G, Lee, J, Thompson, J.R, Botuyan, M.V, Mer, G. | | 登録日 | 2010-10-13 | | 公開日 | 2011-06-22 | | 最終更新日 | 2012-09-26 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
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2FHD
 | | Crystal structure of Crb2 tandem tudor domains | | 分子名称: | DNA repair protein rhp9/CRB2, PHOSPHATE ION | | 著者 | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | | 登録日 | 2005-12-23 | | 公開日 | 2007-01-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Cell(Cambridge,Mass.), 127, 2006
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2B02
 | | Crystal Structure of ARNT PAS-B Domain | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator | | 著者 | Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G. | | 登録日 | 2005-09-12 | | 公開日 | 2006-10-24 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain
To be Published
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6MXZ
 | | Structure of 53BP1 Tudor domains in complex with small molecule UNC3474 | | 分子名称: | FORMIC ACID, N-[3-(tert-butylamino)propyl]-3-(propan-2-yl)benzamide, TP53-binding protein 1 | | 著者 | Cui, G, Botuyan, M.V, Schuller, D.J, Mer, G. | | 登録日 | 2018-10-31 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
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6MXX
 | | Structure of 53BP1 tandem Tudor domains in complex with small molecule UNC2991 | | 分子名称: | FORMIC ACID, N-[3-(tert-butylamino)propyl]-3-iodobenzamide, PHOSPHATE ION, ... | | 著者 | Cui, G, Botuyan, M.V, Mer, G. | | 登録日 | 2018-10-31 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
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6CO1
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6D0L
 | | Structure of human TIRR | | 分子名称: | Tudor-interacting repair regulator protein | | 著者 | Cui, G, Botuyan, M.V, Mer, G. | | 登録日 | 2018-04-10 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
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6MXY
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6MY0
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3SD4
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2LVM
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2LDM
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7LYB
 | | Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c | | 分子名称: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | 登録日 | 2021-03-06 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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