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PDB: 274 件

4KL1
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HCN4 CNBD in complex with cGMP
分子名称: ACETATE ION, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ...
著者Lolicato, M, Arrigoni, C, Zucca, S, Nardini, M, Bucchi, A, Schroeder, I, Simmons, K, Bolognesi, M, DiFrancesco, D, Schwede, F, Fishwick, C.W.G, Johnson, A.P.K, Thiel, G, Moroni, A.
登録日2013-05-07
公開日2014-04-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Nat.Chem.Biol., 10, 2014
5M6I
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Crystal structure of non-cardiotoxic Bence-Jones light chain dimer M8
分子名称: SODIUM ION, light chain dimer
著者Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2016-10-25
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUH
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Crystal structure of an amyloidogenic light chain dimer H7
分子名称: light chain dimer
著者Oberti, L, Rognoni, P, Russo, R, Maritan, M, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2017-01-13
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUD
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Crystal structure of an amyloidogenic light chain dimer H6
分子名称: light chain dimer,IGL@ protein
著者Oberti, L, Bacarizo, J, Maritan, M, Rognoni, P, Bolognesi, M, Ricagno, S.
登録日2017-01-13
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
4NRU
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Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative
分子名称: 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION, RNA dependent RNA polymerase
著者Milani, M, Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Bolognesi, M.
登録日2013-11-27
公開日2014-10-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
4L29
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Structure of wtMHC class I with NY-ESO1 double mutant
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
登録日2013-06-04
公開日2013-12-25
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
2XTL
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BU of 2xtl by Molmil
Structure of the major pilus backbone protein from Streptococcus Agalactiae
分子名称: CELL WALL SURFACE ANCHOR FAMILY PROTEIN, POTASSIUM ION
著者Rinauda, D, Gourlay, L.J, Soriano, M, Grandi, G, Bolognesi, M.
登録日2010-10-11
公開日2011-07-06
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure-Based Approach to Rationally Design a Chimeric Protein for an Effective Vaccine Against Group B Streptococcus Infections.
Proc.Natl.Acad.Sci.USA, 108, 2011
4L3C
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Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
登録日2013-06-05
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
1MOH
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FERRIC MONOMERIC HEMOGLOBIN I (HB I)
分子名称: HYDROSULFURIC ACID, MONOMERIC HEMOGLOBIN I, PROTOPORPHYRIN IX CONTAINING FE
著者Rizzi, M, Wittenberg, J.B, Ascenzi, P, Bolognesi, M.
登録日1996-02-27
公開日1996-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural bases for sulfide recognition in Lucina pectinata hemoglobin I.
J.Mol.Biol., 258, 1996
4NRT
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Human Norovirus polymerase bound to Compound 6 (suramin derivative)
分子名称: 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, hNV-RdRp
著者Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Milani, M, Bolognesi, M.
登録日2013-11-27
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.022 Å)
主引用文献Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
5MVG
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Crystal structure of non-amyloidogenic light chain dimer M7
分子名称: GLYCEROL, light chain dimer
著者Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2017-01-16
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
4O4R
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Murine Norovirus RdRp in complex with PPNDS
分子名称: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, RNA-dependent-RNA-polymerase, SULFATE ION
著者Croci, R, Tarantino, D, Milani, M, Pezzullo, M, Bolognesi, M, Mastrangelo, E.
登録日2013-12-19
公開日2014-11-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.
Febs Lett., 588, 2014
2IG3
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Crystal structure of group III truncated hemoglobin from Campylobacter jejuni
分子名称: ACETATE ION, CYANIDE ION, Group III truncated haemoglobin, ...
著者Nardini, M, Pesce, A, Labarre, M, Ascenzi, P, Guertin, M, Bolognesi, M.
登録日2006-09-22
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural determinants in the group III truncated hemoglobin from Campylobacter jejuni.
J.Biol.Chem., 281, 2006
5M76
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Crystal structure of cardiotoxic Bence-Jones light chain dimer H10
分子名称: BROMIDE ION, light chain dimer
著者Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2016-10-26
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
4MTZ
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BU of 4mtz by Molmil
Structure of XIAP-BIR1 in complex with NF023
分子名称: 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, E3 ubiquitin-protein ligase XIAP, SULFATE ION, ...
著者Cossu, F, Milani, M, Grassi, S, Mastrangelo, E, Bolognesi, M.
登録日2013-09-20
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein-protein interactions in nfkb pathway: novel tools to promote apoptosis in cancer therapy
To be Published
5MTL
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BU of 5mtl by Molmil
Crystal structure of an amyloidogenic light chain
分子名称: light chain dimer,IGL@ protein,IGL@ protein
著者Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2017-01-10
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
2GKM
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BU of 2gkm by Molmil
Crystal structure of Mycobacterium tuberculosis trHbN TyrB10Phe mutant
分子名称: CYANIDE ION, Hemoglobin-like protein HbN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Milani, M, Bolognesi, M.
登録日2006-04-03
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.731 Å)
主引用文献Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
2GKN
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Crystal structure of Mycobacterium tuberculosis trHbN, GlnE11Val mutant
分子名称: CYANIDE ION, Hemoglobin-like protein HbN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Milani, M, Bolognesi, M.
登録日2006-04-03
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
2GL3
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Crystal structure of Mycobacterium tuberculosis trHbN, TyrB10Phe GlnE11Val mutant
分子名称: CYANIDE ION, Hemoglobin-like protein HbN, PHOSPHATE ION, ...
著者Milani, M, Bolognesi, M.
登録日2006-04-04
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
2GLN
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Crystal structure of Mycobacterium tuberculosis trHbN, GlnE11Ala mutant
分子名称: CYANIDE ION, Hemoglobin-like protein HbN, PHOSPHATE ION, ...
著者Milani, M, Bolognesi, M.
登録日2006-04-05
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
3U10
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Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U0Z
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BU of 3u0z by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U11
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Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3QDA
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BU of 3qda by Molmil
Crystal structure of W95L beta-2 microglobulin
分子名称: Beta-2-microglobulin, TRIETHYLENE GLYCOL
著者Ricagno, S, Bellotti, V, Bolognesi, M.
登録日2011-01-18
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
BMC Evol Biol, 11, 2011
3TLR
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Crystal Structure of the tetrameric Beta-2 microglobulin DIMC20 mutant
分子名称: Beta-2-microglobulin, CADMIUM ION, SODIUM ION
著者Colombo, M, Ricagno, S, Bolognesi, M.
登録日2011-08-30
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A recurrent D-strand association interface is observed in beta-2 microglobulin oligomers.
Febs J., 279, 2012

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