1S7K
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![BU of 1s7k by Molmil](/molmil-images/mine/1s7k) | |
3HT5
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![BU of 3ht5 by Molmil](/molmil-images/mine/3ht5) | |
1S7F
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![BU of 1s7f by Molmil](/molmil-images/mine/1s7f) | RimL- Ribosomal L7/L12 alpha-N-protein acetyltransferase crystal form I (apo) | Descriptor: | CHLORIDE ION, MALONIC ACID, acetyl transferase | Authors: | Vetting, M.W, de Carvalho, L.P, Roderick, S.L, Blanchard, J.S. | Deposit date: | 2004-01-29 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A novel dimeric structure of the RimL Nalpha-acetyltransferase from Salmonella typhimurium. J.Biol.Chem., 280, 2005
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1OZP
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![BU of 1ozp by Molmil](/molmil-images/mine/1ozp) | Crystal Structure of Rv0819 from Mycobacterium tuberculosis MshD-Mycothiol Synthase Acetyl-Coenzyme A Complex. | Descriptor: | ACETYL COENZYME *A, hypothetical protein Rv0819 | Authors: | Vetting, M.W, Roderick, S.L, Yu, M, Blanchard, J.S. | Deposit date: | 2003-04-09 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci., 12, 2003
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1P0H
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![BU of 1p0h by Molmil](/molmil-images/mine/1p0h) | Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex | Descriptor: | ACETYL COENZYME *A, COENZYME A, hypothetical protein Rv0819 | Authors: | Vetting, M.W, Roderick, S.L, Yu, M, Blanchard, J.S. | Deposit date: | 2003-04-10 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci., 12, 2003
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1P9L
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![BU of 1p9l by Molmil](/molmil-images/mine/1p9l) | Structure of M. tuberculosis dihydrodipicolinate reductase in complex with NADH and 2,6 PDC | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRIDINE-2,6-DICARBOXYLIC ACID, TETRAETHYLENE GLYCOL, ... | Authors: | Cirilli, M, Zheng, R, Scapin, G, Blanchard, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-05-12 | Release date: | 2003-08-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity. Biochemistry, 42, 2003
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2JEV
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![BU of 2jev by Molmil](/molmil-images/mine/2jev) | Crystal structure of human spermine,spermidine acetyltransferase in complex with a bisubstrate analog (N1-acetylspermine-S-CoA). | Descriptor: | (3R)-27-AMINO-3-HYDROXY-2,2-DIMETHYL-4,8,14-TRIOXO-12-THIA-5,9,15,19,24-PENTAAZAHEPTACOS-1-YL [(2S,3R,4S,5S)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, DIAMINE ACETYLTRANSFERASE 1 | Authors: | Hegde, S.S, Chandler, J, Vetting, M.W, Yu, M, Blanchard, J.S. | Deposit date: | 2007-01-23 | Release date: | 2007-06-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanistic and Structural Analysis of Human Spermidine/Spermine N(1)-Acetyltransferase. Biochemistry, 46, 2007
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1BW9
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![BU of 1bw9 by Molmil](/molmil-images/mine/1bw9) | PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE | Descriptor: | 1,2-ETHANEDIOL, 3-PHENYLPYRUVIC ACID, ISOPROPYL ALCOHOL, ... | Authors: | Vanhooke, J.L, Thoden, J.B, Brunhuber, N.M.W, Blanchard, J.L, Holden, H.M. | Deposit date: | 1998-10-01 | Release date: | 1999-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism. Biochemistry, 38, 1999
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2GKE
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![BU of 2gke by Molmil](/molmil-images/mine/2gke) | Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor LL-AziDAP | Descriptor: | (2S,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, ACETIC ACID, Diaminopimelate epimerase, ... | Authors: | Pillai, B, Cherney, M.M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C, James, M.N. | Deposit date: | 2006-04-01 | Release date: | 2006-05-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GKJ
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![BU of 2gkj by Molmil](/molmil-images/mine/2gkj) | Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor DL-AZIDAP | Descriptor: | (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, ACETIC ACID, Diaminopimelate epimerase | Authors: | Pillai, B, Cherney, M.M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C, James, M.N. | Deposit date: | 2006-04-02 | Release date: | 2006-05-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1BXG
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![BU of 1bxg by Molmil](/molmil-images/mine/1bxg) | PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND BETA-PHENYLPROPIONATE | Descriptor: | HYDROCINNAMIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHENYLALANINE DEHYDROGENASE, ... | Authors: | Vanhooke, J.L, Thoden, J.B, Brunhuber, N.M.W, Blanchard, J.L, Holden, H.M. | Deposit date: | 1998-10-02 | Release date: | 1999-05-18 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism. Biochemistry, 38, 1999
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2C27
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![BU of 2c27 by Molmil](/molmil-images/mine/2c27) | The Structure of Mycothiol Synthase in Complex with des- AcetylMycothiol and CoenzymeA. | Descriptor: | (1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside, ACETYL COENZYME *A, COENZYME A, ... | Authors: | Vetting, M.W, Yu, M, Rendle, P.M, Blanchard, J.S. | Deposit date: | 2005-09-26 | Release date: | 2005-12-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Substrate-Induced Conformational Change of Mycobacterium Tuberculosis Mycothiol Synthase. J.Biol.Chem., 281, 2006
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2W7Z
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![BU of 2w7z by Molmil](/molmil-images/mine/2w7z) | Structure of the pentapeptide repeat protein EfsQnr, a DNA gyrase inhibitor. Free amines modified by cyclic pentylation with glutaraldehyde. | Descriptor: | CHLORIDE ION, PENTAPEPTIDE REPEAT FAMILY PROTEIN | Authors: | Vetting, M.W, Hegde, S.S, Blanchard, J.S. | Deposit date: | 2009-01-06 | Release date: | 2009-05-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallization of a Pentapeptide-Repeat Protein by Reductive Cyclic Pentylation of Free Amines with Glutaraldehyde. Acta Crystallogr.,Sect.D, 65, 2009
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2VQY
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![BU of 2vqy by Molmil](/molmil-images/mine/2vqy) | Structure of AAC(6')-Ib in complex with Parmomycin and AcetylCoA. | Descriptor: | AAC(6')-IB, ACETYL COENZYME *A, CALCIUM ION, ... | Authors: | Vetting, M.W, Park, C.H, Hedge, S.S, Hooper, D.C, Blanchard, J.S. | Deposit date: | 2008-03-20 | Release date: | 2008-09-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanistic and Structural Analysis of Aminoglycoside N-Acetyltransferase Aac(6')-Ib and its Bifunctional, Fluoroquinolone-Active Aac(6')-Ib-Cr Variant. Biochemistry, 47, 2008
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2X9Q
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![BU of 2x9q by Molmil](/molmil-images/mine/2x9q) | |
2VBQ
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![BU of 2vbq by Molmil](/molmil-images/mine/2vbq) | Structure of AAC(6')-Iy in complex with bisubstrate analog CoA-S- monomethyl-acetylneamine. | Descriptor: | (3R,9Z)-17-[(2R,3S,4R,5R,6R)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-3,4-dihydroxytetrahydro-2H-pyran-2-yl]-3-hydroxy-2,2-dimethyl-4,8,15-trioxo-12-thia-5,9,16-triazaheptadec-9-en-1-yl [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE, GLYCEROL, ... | Authors: | Vetting, M.W, Magalhaes, M.L, Freiburger, L, Gao, F, Auclair, K, Blanchard, J.S. | Deposit date: | 2007-09-14 | Release date: | 2008-01-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic and Structural Analysis of Bisubstrate Inhibition of the Salmonella Enterica Aminoglycoside 6'-N-Acetyltransferase. Biochemistry, 47, 2008
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1DIH
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![BU of 1dih by Molmil](/molmil-images/mine/1dih) | |
1KGQ
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![BU of 1kgq by Molmil](/molmil-images/mine/1kgq) | Crystal Structure of Tetrahydrodipicolinate N-Succinyltransferase in Complex with L-2-aminopimelate and Succinamide-CoA | Descriptor: | (2S)-2-aminoheptanedioic acid, 2,3,4,5-TETRAHYDROPYRIDINE-2-CARBOXYLATE N-SUCCINYLTRANSFERASE, SUCCINAMIDE-COA | Authors: | Beaman, T.W, Vogel, K.W, Drueckhammer, D.G, Blanchard, J.S, Roderick, S.L. | Deposit date: | 2001-11-28 | Release date: | 2002-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. Protein Sci., 11, 2002
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2CNT
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![BU of 2cnt by Molmil](/molmil-images/mine/2cnt) | RimI - Ribosomal S18 N-alpha-protein acetyltransferase in complex with CoenzymeA. | Descriptor: | COENZYME A, GLYCEROL, MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18, ... | Authors: | Vetting, M.W, Bareich, D.C, Yu, M, Blanchard, J.S. | Deposit date: | 2006-05-23 | Release date: | 2007-06-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Rimi from Salmonella Typhimurium Lt2, the Gnat Responsible for N{Alpha}- Acetylation of Ribosomal Protein S18. Protein Sci., 17, 2008
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2CNM
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![BU of 2cnm by Molmil](/molmil-images/mine/2cnm) | RimI - Ribosomal S18 N-alpha-protein acetyltransferase in complex with a bisubstrate inhibitor (Cterm-Arg-Arg-Phe-Tyr-Arg-Ala-N-alpha- acetyl-S-CoA). | Descriptor: | 30S RIBOSOMAL PROTEIN S18, COENZYME A, MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18 | Authors: | Vetting, M.W, Yu, M, Bareich, D.C, Blanchard, J.S. | Deposit date: | 2006-05-22 | Release date: | 2007-05-22 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Rimi from Salmonella Typhimurium Lt2, the Gnat Responsible for N{Alpha}- Acetylation of Ribosomal Protein S18. Protein Sci., 17, 2008
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2CNS
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![BU of 2cns by Molmil](/molmil-images/mine/2cns) | RimI - Ribosomal S18 N-alpha-protein acetyltransferase in complex with acetylCoA. | Descriptor: | ACETYL COENZYME *A, MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18, PHOSPHATE ION | Authors: | Vetting, M.W, Bareich, D.C, Yu, M, Blanchard, J.S. | Deposit date: | 2006-05-23 | Release date: | 2007-06-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Rimi from Salmonella Typhimurium Lt2, the Gnat Responsible for N{Alpha}- Acetylation of Ribosomal Protein S18. Protein Sci., 17, 2008
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1KGT
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![BU of 1kgt by Molmil](/molmil-images/mine/1kgt) | Crystal Structure of Tetrahydrodipicolinate N-Succinyltransferase in Complex with Pimelate and Succinyl-CoA | Descriptor: | 2,3,4,5-TETRAHYDROPYRIDINE-2-CARBOXYLATE N-SUCCINYLTRANSFERASE, PIMELIC ACID, SUCCINYL-COENZYME A | Authors: | Beaman, T.W, Vogel, K.W, Drueckhammer, D.G, Blanchard, J.S, Roderick, S.L. | Deposit date: | 2001-11-28 | Release date: | 2002-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. Protein Sci., 11, 2002
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4LZJ
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![BU of 4lzj by Molmil](/molmil-images/mine/4lzj) | Crystal Structure of MurQ from H.influenzae with bound inhibitor | Descriptor: | 2-(acetylamino)-3-O-[(1R)-1-carboxyethyl]-2-deoxy-6-O-phosphono-D-glucitol, N-acetylmuramic acid 6-phosphate etherase, PHOSPHATE ION | Authors: | Hazra, S, Blanchard, J. | Deposit date: | 2013-07-31 | Release date: | 2014-02-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.405 Å) | Cite: | Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor. Biochemistry, 52, 2013
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1V0C
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![BU of 1v0c by Molmil](/molmil-images/mine/1v0c) | Structure of AAC(6')-Ib in complex with Kanamycin C and AcetylCoA. | Descriptor: | AAC(6')-IB, ACETYL COENZYME *A, CALCIUM ION, ... | Authors: | Vetting, M.W, Park, C.H, Hedge, S.S, Hooper, D.C, Blanchard, J.S. | Deposit date: | 2008-03-20 | Release date: | 2008-09-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanistic and Structural Analysis of Aminoglycoside N-Acetyltransferase Aac(6')-Ib and its Bifunctional, Fluoroquinolone-Active Aac(6')-Ib-Cr Variant. Biochemistry, 47, 2008
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2J8K
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![BU of 2j8k by Molmil](/molmil-images/mine/2j8k) | Structure of the fusion of NP275 and NP276, pentapeptide repeat proteins from Nostoc punctiforme | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NP275-NP276, SULFATE ION | Authors: | Vetting, M.W, Hegde, S.S, Hazleton, K.Z, Blanchard, J.S. | Deposit date: | 2006-10-25 | Release date: | 2006-12-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Characterization of the Fusion of Two Pentapeptide Repeat Proteins, Np275 and Np276, from Nostoc Punctiforme: Resurrection of an Ancestral Protein. Protein Sci., 16, 2007
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