2JEV
Crystal structure of human spermine,spermidine acetyltransferase in complex with a bisubstrate analog (N1-acetylspermine-S-CoA).
Summary for 2JEV
Entry DOI | 10.2210/pdb2jev/pdb |
Related | 2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T |
Descriptor | DIAMINE ACETYLTRANSFERASE 1, (3R)-27-AMINO-3-HYDROXY-2,2-DIMETHYL-4,8,14-TRIOXO-12-THIA-5,9,15,19,24-PENTAAZAHEPTACOS-1-YL [(2S,3R,4S,5S)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE (3 entities in total) |
Functional Keywords | acyltransferase, acetyltransferase, gcn5 related n-acetyltransferase, polyamine biosynthesis, gnat, spermine, spermidine, transferase, bisubstrate |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 42680.32 |
Authors | Hegde, S.S.,Chandler, J.,Vetting, M.W.,Yu, M.,Blanchard, J.S. (deposition date: 2007-01-23, release date: 2007-06-05, Last modification date: 2023-12-13) |
Primary citation | Hegde, S.S.,Chandler, J.,Vetting, M.W.,Yu, M.,Blanchard, J.S. Mechanistic and Structural Analysis of Human Spermidine/Spermine N(1)-Acetyltransferase. Biochemistry, 46:7187-, 2007 Cited by PubMed: 17516632DOI: 10.1021/BI700256Z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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