2VQY

Structure of AAC(6')-Ib in complex with Parmomycin and AcetylCoA.

Summary for 2VQY

Entry DOI	10.2210/pdb2vqy/pdb
Related	1V0C 2BUE
Descriptor	AAC(6')-IB, ACETYL COENZYME *A, PAROMOMYCIN, ... (5 entities in total)
Functional Keywords	gnat, transferase, aminoglycoside, fluoroquinolone, acetyltransferase, antibiotic resistance
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	23890.39
Authors	Vetting, M.W.,Park, C.H.,Hedge, S.S.,Hooper, D.C.,Blanchard, J.S. (deposition date: 2008-03-20, release date: 2008-09-02, Last modification date: 2024-05-08)
Primary citation	Vetting, M.W.,Park, C.H.,Hegde, S.S.,Jacoby, G.A.,Hooper, D.C.,Blanchard, J.S. Mechanistic and Structural Analysis of Aminoglycoside N-Acetyltransferase Aac(6')-Ib and its Bifunctional, Fluoroquinolone-Active Aac(6')-Ib-Cr Variant. Biochemistry, 47:9825-, 2008 Cited by PubMed: 18710261 DOI: 10.1021/BI800664X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation