2VQY

Structure of AAC(6')-Ib in complex with Parmomycin and AcetylCoA.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016410	molecular_function	N-acyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0016779	molecular_function	nucleotidyltransferase activity
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
A	0047663	molecular_function	aminoglycoside 6'-N-acetyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	BINDING SITE FOR RESIDUE ACO A1200

Chain	Residue
A	HIS44
A	GLY127
A	LEU128
A	GLY129
A	THR130
A	THR151
A	ASP152
A	ASN157
A	LEU158
A	ARG159
A	ALA160
A	TRP48
A	ARG162
A	TYR164
A	LYS166
A	PAR1201
A	HOH2192
A	HOH2193
A	HOH2194
A	HOH2195
A	HOH2196
A	ASP115
A	GLN116
A	LEU117
A	LEU118
A	LEU124
A	GLY125
A	LYS126

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site_id	AC2
Number of Residues	26
Details	BINDING SITE FOR RESIDUE PAR A1201

Chain	Residue
A	TRP48
A	GLY50
A	GLN64
A	TYR65
A	LEU70
A	GLU73
A	VAL75
A	GLN91
A	TYR93
A	SER98
A	TRP102
A	TRP103
A	ASP115
A	ASP152
A	ACO1200
A	HOH2061
A	HOH2073
A	HOH2176
A	HOH2177
A	HOH2197
A	HOH2198
A	HOH2199
A	HOH2200
A	HOH2201
A	HOH2202
A	HOH2204

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A1202

Chain	Residue
A	GLU145
A	ASP179
A	HOH2140
A	HOH2146
A	HOH2147
A	HOH2178
A	HOH2180

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A1203

Chain	Residue
A	GLU38
A	ARG194
A	SER197
A	ALA199
A	HOH2024
A	HOH2189

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