2GKJ

Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor DL-AZIDAP

Summary for 2GKJ

Entry DOI	10.2210/pdb2gkj/pdb
Related	2GKE
Descriptor	Diaminopimelate epimerase, (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, ACETIC ACID, ... (4 entities in total)
Functional Keywords	enzyme-inhibitor complex, covalently bound inhibitor, isomerase
Biological source	Haemophilus influenzae
Cellular location	Cytoplasm: P44859
Total number of polymer chains	1
Total formula weight	30603.80
Authors	Pillai, B.,Cherney, M.M.,Diaper, C.M.,Sutherland, A.,Blanchard, J.S.,Vederas, J.C.,James, M.N. (deposition date: 2006-04-02, release date: 2006-05-16, Last modification date: 2011-07-13)
Primary citation	Pillai, B.,Cherney, M.M.,Diaper, C.M.,Sutherland, A.,Blanchard, J.S.,Vederas, J.C.,James, M.N. Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target. Proc.Natl.Acad.Sci.Usa, 103:8668-8673, 2006 Cited by PubMed: 16723397 DOI: 10.1073/pnas.0602537103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation