2GKE
Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor LL-AziDAP
Summary for 2GKE
Entry DOI | 10.2210/pdb2gke/pdb |
Related | 2GKJ |
Descriptor | Diaminopimelate epimerase, (2S,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, GLYCEROL, ... (5 entities in total) |
Functional Keywords | enzyme-inhibitor complex, covalently bound inhibitor, isomerase |
Biological source | Haemophilus influenzae |
Cellular location | Cytoplasm: P44859 |
Total number of polymer chains | 1 |
Total formula weight | 30755.95 |
Authors | Pillai, B.,Cherney, M.M.,Diaper, C.M.,Sutherland, A.,Blanchard, J.S.,Vederas, J.C.,James, M.N. (deposition date: 2006-04-01, release date: 2006-05-16, Last modification date: 2011-07-13) |
Primary citation | Pillai, B.,Cherney, M.M.,Diaper, C.M.,Sutherland, A.,Blanchard, J.S.,Vederas, J.C.,James, M.N. Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target. Proc.Natl.Acad.Sci.Usa, 103:8668-8673, 2006 Cited by PubMed: 16723397DOI: 10.1073/pnas.0602537103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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