4N1U
 
 | | Structure of human MTH1 in complex with TH588 | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION | | 著者 | Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. | | 登録日 | 2013-10-04 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Nature, 508, 2014
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4N1T
 | | Structure of human MTH1 in complex with TH287 | | 分子名称: | 6-(2,3-dichlorophenyl)-N~4~-methylpyrimidine-2,4-diamine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | | 著者 | Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. | | 登録日 | 2013-10-04 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Nature, 508, 2014
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5TPB
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5TPC
 | | Binding domain of BoNT/A complexed with ganglioside | | 分子名称: | Botulinum neurotoxin type A, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose | | 著者 | Berntsson, R.P.-A, Svensson, L.M, Stenmark, P. | | 登録日 | 2016-10-20 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A.
J. Am. Chem. Soc., 139, 2017
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4DVE
 | | Crystal structure at 2.1 A of the S-component for biotin from an ECF-type ABC transporter | | 分子名称: | BIOTIN, Biotin transporter BioY, nonyl beta-D-glucopyranoside | | 著者 | Berntsson, R.P.-A, ter Beek, J, Majsnerowska, M, Duurkens, R, Puri, P, Poolman, B, Slotboom, D.J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-08-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural divergence of paralogous S components from ECF-type ABC transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FAJ
 | | Structure and mode of peptide binding of pheromone receptor PrgZ | | 分子名称: | GLYCEROL, PrgZ, Sex pheromone cCF10, ... | | 著者 | Berntsson, R.P.-A, Schuurman-Wolters, G.K, Dunny, K, Slotboom, D.J, Poolman, B. | | 登録日 | 2012-05-22 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Mode of Peptide Binding of Pheromone Receptor PrgZ.
J.Biol.Chem., 287, 2012
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5LR0
 | | Binding domain of Botulinum Neurotoxin DC in complex with SialylT | | 分子名称: | Botulinum neurotoxin D/C protein, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | | 著者 | Berntsson, R.P.-A, Stenmark, P. | | 登録日 | 2016-08-18 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.
Nat Commun, 8, 2017
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3RYB
 | | Lactococcal OppA complexed with SLSQSLSQS | | 分子名称: | Oligopeptide, Oligopeptide-binding protein oppA | | 著者 | Berntsson, R.P.-A, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | | 登録日 | 2011-05-11 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA.
J.Bacteriol., 193, 2011
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3RYA
 | | Lactococcal OppA complexed with SLSQLSSQS | | 分子名称: | Oligopeptide, Oligopeptide-binding protein oppA | | 著者 | Berntsson, R.P.-A, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | | 登録日 | 2011-05-11 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA.
J.Bacteriol., 193, 2011
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4ISR
 | | Binding domain of Botulinum neurotoxin DC in complex with rat synaptotagmin II | | 分子名称: | Neurotoxin, SULFATE ION, Synaptotagmin-2 | | 著者 | Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P. | | 登録日 | 2013-01-17 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
Structure, 21, 2013
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4ISQ
 | | Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I | | 分子名称: | GLYCEROL, Neurotoxin, SULFATE ION, ... | | 著者 | Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P. | | 登録日 | 2013-01-17 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
Structure, 21, 2013
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4KA7
 | | Structure of Organellar OligoPeptidase (E572Q) in complex with an endogenous substrate | | 分子名称: | CHLORIDE ION, GLYCEROL, Oligopeptidase A, ... | | 著者 | Berntsson, R.P.-A, Kmiec, B, Teixeira, P.F, Svensson, L.M, Bakali, A, Glaser, E, Stenmark, P. | | 登録日 | 2013-04-22 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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4LHF
 | | Crystal structure of a DNA binding protein from phage P2 | | 分子名称: | Regulatory protein cox | | 著者 | Berntsson, R.P.-A, Odegrip, R, Sehlen, W, Skaar, K, Svensson, L.M, Massad, T, Haggard-Ljungquist, E, Stenmark, P. | | 登録日 | 2013-07-01 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structural insight into DNA binding and oligomerization of the multifunctional Cox protein of bacteriophage P2.
Nucleic Acids Res., 42, 2014
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4KA8
 | | Structure of Organellar OligoPeptidase | | 分子名称: | CHLORIDE ION, GLYCEROL, Oligopeptidase A, ... | | 著者 | Berntsson, R.P.-A, Kmiec, B, Teixeira, P.F, Svensson, L.M, Bakali, A, Glaser, E, Stenmark, P. | | 登録日 | 2013-04-22 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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3FTO
 | | Crystal structure of OppA in a open conformation | | 分子名称: | Oligopeptide-binding protein oppA | | 著者 | Berntsson, R.P.-A, Oktaviani, N.A, Fusetti, F, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | | 登録日 | 2009-01-13 | | 公開日 | 2009-03-31 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Selenomethionine incorporation in proteins expressed in Lactococcus lactis.
Protein Sci., 18, 2009
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3DRI
 | | Crystal structure of Lactococcal OppA co-crystallized with an octamer peptide in an open conformation | | 分子名称: | Oligopeptide-binding protein oppA, peptide AASASA | | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | | 登録日 | 2008-07-11 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
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3DRJ
 | | Crystal structure of Lactococcal OppA co-crystallized with pTH-related peptide in an open conformation | | 分子名称: | Oligopeptide-binding protein oppA, pTH-related peptide | | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | | 登録日 | 2008-07-11 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
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3DRH
 | | Crystal structure of Lactococcal OppA co-crystallized with Leu-enkephalin in an open conformation | | 分子名称: | Oligopeptide-binding protein oppA, peptide AAAAAA | | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | | 登録日 | 2008-07-11 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
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3DRF
 | | Lactococcal OppA complexed with an endogenous peptide in the closed conformation | | 分子名称: | Oligopeptide-binding protein oppA, endogenous peptide | | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | | 登録日 | 2008-07-11 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
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3DRG
 | | Lactococcal OppA complexed with bradykinin in the closed conformation | | 分子名称: | Bradykinin, CHLORIDE ION, Oligopeptide-binding protein oppA | | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | | 登録日 | 2008-07-11 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
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3DRK
 | | Crystal structure of Lactococcal OppA co-crystallized with Neuropeptide S in an open conformation | | 分子名称: | Neuropeptide S, Oligopeptide-binding protein oppA | | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | | 登録日 | 2008-07-11 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA
Embo J., 28, 2009
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8A1B
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8A1C
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8BEG
 | | Structure of Ig-like domains from PrgB | | 分子名称: | MAGNESIUM ION, PrgB | | 著者 | Jarva, M, Schmitt, A, Berntsson, R.P.-A. | | 登録日 | 2022-10-21 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural foundation for the role of enterococcal PrgB in conjugation, biofilm formation, and virulence.
Elife, 12, 2023
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8S0U
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