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PDB: 171 件

1FNN
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CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM
分子名称: ADENOSINE-5'-DIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6, MAGNESIUM ION
著者Liu, J, Smith, C.L, DeRyckere, D, DeAngelis, K, Martin, G.S, Berger, J.M.
登録日2000-08-22
公開日2000-10-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control.
Mol.Cell, 6, 2000
1JHN
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Crystal Structure of the Lumenal Domain of Calnexin
分子名称: CALCIUM ION, calnexin
著者Schrag, J.D, Bergeron, J.M, Li, Y, Borisova, S, Hahn, M, Thomas, D.Y, Cygler, M.
登録日2001-06-28
公開日2001-10-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of calnexin, an ER chaperone involved in quality control of protein folding.
Mol.Cell, 8, 2001
4FM9
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Human topoisomerase II alpha bound to DNA
分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ...
著者Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M.
登録日2012-06-15
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage.
J.Mol.Biol., 424, 2012
4GFH
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Topoisomerase II-DNA-AMPPNP complex
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), ...
著者Schmidt, B.H, Osheroff, N, Berger, J.M.
登録日2012-08-03
公開日2012-10-03
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (4.408 Å)
主引用文献Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity.
Nat.Struct.Mol.Biol., 19, 2012
4KM5
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X-ray crystal structure of human cyclic GMP-AMP synthase (cGAS)
分子名称: Cyclic GMP-AMP synthase, ZINC ION
著者Kranzusch, P.J, Lee, A.S.Y, Berger, J.M, Doudna, J.A.
登録日2013-05-08
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
Cell Rep, 3, 2013
4MN4
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Structural Basis for the MukB-topoisomerase IV Interaction
分子名称: Chromosome partition protein MukB, DNA topoisomerase 4 subunit A
著者Vos, S.M, Stewart, N.K, Oakley, M.G, Berger, J.M.
登録日2013-09-09
公開日2013-10-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo.
Embo J., 32, 2013
3KML
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Circular Permutant of the Tobacco Mosaic Virus
分子名称: Coat protein
著者Duderstadt, K.E, Dedeo, M.T, Francis, M.B, Berger, J.M.
登録日2009-11-10
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献Nanoscale protein assemblies from a circular permutant of the tobacco mosaic virus.
Nano Lett., 10, 2010
3L4J
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Topoisomerase II-DNA cleavage complex, apo
分子名称: 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M.
登録日2009-12-20
公開日2010-05-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
3NO0
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Aquifex aeolicus type IIA topoisomerase C-terminal domain
分子名称: DNA gyrase subunit A, GLYCEROL, NITRATE ION
著者Tretter, E.M, Lerman, J.C, Berger, J.M.
登録日2010-06-24
公開日2010-12-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3004 Å)
主引用文献A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KDE
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Crystal structure of the THAP domain from D. melanogaster P-element transposase in complex with its natural DNA binding site
分子名称: 5'-D(*(BRU)P*CP*CP*AP*CP*TP*TP*AP*AP*C)-3', 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3', Transposable element P transposase, ...
著者Sabogal, A, Lyubimov, A.Y, Berger, J.M, Rio, D.C.
登録日2009-10-22
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
Nat.Struct.Mol.Biol., 17, 2010
3NUH
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A domain insertion in E. coli GyrB adopts a novel fold that plays a critical role in gyrase function
分子名称: DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION
著者Schoeffler, A.J, May, A.P, Berger, J.M.
登録日2010-07-06
公開日2010-08-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function.
Nucleic Acids Res., 38, 2010
3L4K
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Topoisomerase II-DNA cleavage complex, metal-bound
分子名称: 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ...
著者Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M.
登録日2009-12-20
公開日2010-05-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
4FTH
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Crystal Structure of NtrC4 DNA-binding domain bound to double-stranded DNA
分子名称: 5'-D(*AP*CP*TP*TP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*AP*AP*AP*TP*GP*CP*AP*T)-3', 5'-D(P*GP*AP*TP*GP*CP*AP*TP*TP*TP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*AP*A)-3', Transcriptional regulator (NtrC family)
著者Vidangos, N.K, Heideker, J, Lyubimov, A.Y, Lamers, M, Huo, Y, Pelton, J.G, Ton, J, Gralla, J.D, Kuriyan, J, Berger, J.M, Wemmer, D.E.
登録日2012-06-27
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献DNA Recognition by a sigma (54) Transcriptional Activator from Aquifex aeolicus.
J.Mol.Biol., 426, 2014
3PEU
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S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 H337R and IP6
分子名称: ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3PEW
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S. cerevisiae Dbp5 L327V bound to RNA and ADP BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3PEV
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S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 and IP6
分子名称: ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3PEY
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S. cerevisiae Dbp5 bound to RNA and ADP BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2010-10-27
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
3RRN
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S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2011-04-29
公開日2011-05-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.001 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
3RRM
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S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ...
著者Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
登録日2011-04-29
公開日2011-05-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
3R8F
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Replication initiator DnaA bound to AMPPCP and single-stranded DNA
分子名称: 5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', Chromosomal replication initiator protein dnaA, MAGNESIUM ION, ...
著者Duderstadt, K.E, Chuang, K, Berger, J.M.
登録日2011-03-23
公開日2011-09-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.366 Å)
主引用文献DNA stretching by bacterial initiators promotes replication origin opening.
Nature, 478, 2011
4LIM
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Crystal structure of the catalytic subunit of yeast primase
分子名称: DNA primase small subunit, ZINC ION
著者Vaithiyalingam, S, Chazin, W.J, Berger, J.M, Corn, J, Stephenson, S.
登録日2013-07-02
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014

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