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PDB: 5 件

1DXW
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structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound
分子名称: N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, SERINE PROTEASE, ZINC ION
著者Barbato, G, Cicero, D.O, Cordier, F, Narjes, F, Gerlach, B, Sambucini, S, Grzesiek, S, Matassa, V.G, Defrancesco, R, Bazzo, R.
登録日2000-01-17
公開日2001-01-12
最終更新日2020-01-15
実験手法SOLUTION NMR
主引用文献Inhibitor Binding Induces Active Site Stabilisation of the Hcv Ns3 Protein Serine Protease Domain
Embo J., 19, 2000
1MZI
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Solution ensemble structures of HIV-1 gp41 2F5 mAb epitope
分子名称: 2F5 epitope of HIV-1 gp41 fusion protein
著者Barbato, G, Bianchi, E, Ingallinella, P, Hurni, W.H, Miller, M.D, Ciliberto, G, Cortese, R, Bazzo, R, Shiver, J.W, Pessi, A.
登録日2002-10-08
公開日2003-09-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion.
J.Mol.Biol., 330, 2003
1BT7
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THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES
分子名称: NS3 SERINE PROTEASE, ZINC ION
著者Barbato, G, Cicero, D.O, Nardi, M.C, Steinkuhler, C, Cortese, R, De Francesco, R, Bazzo, R.
登録日1998-09-01
公開日1999-06-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism.
J.Mol.Biol., 289, 1999
2UV0
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Structure of the P. aeruginosa LasR ligand-binding domain bound to its autoinducer
分子名称: N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, TRANSCRIPTIONAL ACTIVATOR PROTEIN LASR
著者Bottomley, M.J, Muraglia, E, Bazzo, R, Carfi, A.
登録日2007-03-08
公開日2007-03-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Insights Into Quorum Sensing in the Human Pathogen Pseudomonas Aeruginosa from the Structure of the Virulence Regulator Lasr Bound to its Autoinducer.
J.Biol.Chem., 282, 2007
2K1Q
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NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor
分子名称: NS3 PROTEASE, PHENETHYLAMIDE, ZINC ION
著者Eliseo, T, Gallo, M, Pennestri, M, Bazzo, R, Cicero, D.O.
登録日2008-03-13
公開日2009-02-03
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor.
J.Mol.Biol., 385, 2009

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件を2024-11-06に公開中

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