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PDB: 42 件

6EVQ
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solution NMR structure of EB1 C terminus (191-260) with a small molecule bound into the SxIP binding site
分子名称: (2~{R})-2-[(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)sulfanyl]-~{N}-(furan-2-ylmethyl)propanamide, Microtubule-associated protein RP/EB family member 1
著者Barsukov, I.L, Almeida, T.B.
登録日2017-11-02
公開日2018-02-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.
Sci Rep, 7, 2017
6EVI
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solution NMR structure of EB1 C terminus (191-260)
分子名称: Microtubule-associated protein RP/EB family member 1
著者Barsukov, I.L, Almeida, T.B.
登録日2017-11-01
公開日2018-02-07
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.
Sci Rep, 7, 2017
2LNK
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BU of 2lnk by Molmil
Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA
分子名称: Myosin heavy chain, non-muscle IIa, Protein S100-A4
著者Barsukov, I.L, Elliott, P.R.
登録日2011-12-30
公開日2012-04-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Asymmetric Mode of Ca(2+)-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling.
Structure, 20, 2012
2K8G
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BU of 2k8g by Molmil
Solution structure of RRM2 domain of PABP1
分子名称: Polyadenylate-binding protein 1
著者Barsukov, I, Parnham, S.
登録日2008-09-09
公開日2009-10-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of RRM2 domain of PABP1
To be Published
1T01
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BU of 1t01 by Molmil
Vinculin complexed with the VBS1 helix from talin
分子名称: Talin 1, unnamed protein product
著者Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J.
登録日2004-04-07
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
7OLG
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EB1 bound to MACF peptide
分子名称: 11MACF, Microtubule-associated protein RP/EB family member 1
著者Almeida, T.B, Barsukov, I.L.
登録日2021-05-20
公開日2022-06-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献EB1 bound to MACF peptide
To Be Published
5G4X
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BU of 5g4x by Molmil
The crystal structure of the SHANK3 N-terminus
分子名称: 1,2-ETHANEDIOL, SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3
著者Zacharchenko, T, Barsukov, I.
登録日2016-05-17
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.166 Å)
主引用文献SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
Nat. Cell Biol., 19, 2017
2QDQ
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BU of 2qdq by Molmil
Crystal structure of the talin dimerisation domain
分子名称: Talin-1
著者Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C.
登録日2007-06-21
公開日2008-01-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of the C-terminal actin-binding domain of talin.
Embo J., 27, 2008
2X0C
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Crystal Structure of the R7R8 domains of Talin
分子名称: TALIN-1
著者Gingras, A.R, Goult, B.T, Bate, N, Barsukov, I.L, Emsley, J, Critchely, D.R.
登録日2009-12-08
公開日2010-07-07
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Central Region of Talin Has a Unique Fold that Binds Vinculin and Actin.
J.Biol.Chem., 285, 2010
5FZT
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The crystal structure of R7R8 in complex with a DLC1 fragment.
分子名称: MALONATE ION, RHO GTPASE-ACTIVATING PROTEIN 7, TALIN-1
著者Zacharchenko, T, Qian, X, Goult, B.T, Jethwa, D, Almeida, T, Ballestrem, C, Critchley, D.R, Lowy, D.R, Barsukov, I.L.
登録日2016-03-15
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex.
Structure, 24, 2016
3IVF
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Crystal structure of the talin head FERM domain
分子名称: Talin-1
著者Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
登録日2009-09-01
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
3PV1
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Crystal structure of the USP15 DUSP-UBL domains
分子名称: ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15
著者Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L.
登録日2010-12-06
公開日2011-11-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
Febs Lett., 585, 2011
3C1V
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The 1.5 A Crystal structure of Ca2+-bound S100A4
分子名称: CALCIUM ION, Protein S100-A4
著者Gingras, A.R, Barsukov, I.L.
登録日2008-01-24
公開日2008-04-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the Ca(2+)-form and Ca(2+)-binding kinetics of metastasis-associated protein, S100A4
Febs Lett., 582, 2008
1BCT
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BU of 1bct by Molmil
THREE-DIMENSIONAL STRUCTURE OF PROTEOLYTIC FRAGMENT 163-231 OF BACTERIOOPSIN DETERMINED FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION
分子名称: BACTERIORHODOPSIN
著者Nolde, D.E, Barsukov, I.L, Lomize, A.L, Arseniev, A.S.
登録日1993-07-07
公開日1994-04-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of proteolytic fragment 163-231 of bacterioopsin determined from nuclear magnetic resonance data in solution.
Eur.J.Biochem., 206, 1992
1AO8
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
分子名称: DIHYDROFOLATE REDUCTASE, METHOTREXATE
著者Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J.
登録日1997-07-22
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277, 1998
1SJ7
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BU of 1sj7 by Molmil
Crystal Structure of Talin Rod 482-655
分子名称: PLATINUM (II) ION, Talin 1
著者Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J.
登録日2004-03-03
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
EMBO J., 23, 2004
4A3P
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BU of 4a3p by Molmil
Structure of USP15 DUSP-UBL deletion mutant
分子名称: ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
著者Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
登録日2011-10-03
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
1SJ8
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Solution Structure of the R1R2 Domains of Talin
分子名称: Talin 1
著者Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J.
登録日2004-03-03
公開日2004-08-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
EMBO J., 23, 2004
1U89
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BU of 1u89 by Molmil
Solution structure of VBS2 fragment of talin
分子名称: Talin 1
著者Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
登録日2004-08-05
公開日2005-01-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1U6H
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Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879)
分子名称: Talin, Vinculin
著者Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
登録日2004-07-30
公開日2005-01-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
3ZDL
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Vinculin head (1-258) in complex with a RIAM fragment
分子名称: AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN, VINCULIN
著者Zacharchenko, T, Elliott, P.R, Goult, B.T, Bate, N, Critchely, D.R, Barsukov, I.L.
登録日2012-11-28
公開日2013-02-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
4A3O
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BU of 4a3o by Molmil
Crystal structure of the USP15 DUSP-UBL monomer
分子名称: GLYCEROL, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
著者Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
登録日2011-10-03
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
1GRM
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BU of 1grm by Molmil
REFINEMENT OF THE SPATIAL STRUCTURE OF THE GRAMICIDIN A TRANSMEMBRANE ION-CHANNEL (RUSSIAN)
分子名称: GRAMICIDIN A
著者Arseniev, A.S, Barsukov, I.L, Lomize, A.L, Orekhov, V.Y, Bystrov, V.F.
登録日1993-10-18
公開日1994-01-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Refinement of the Spatial Structure of the Gramicidin a Ion Channel
Biol.Membr.(Ussr), 18, 1992
1RE6
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BU of 1re6 by Molmil
Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands
分子名称: dynein light chain 2
著者Day, C.L, Puthalakath, H, Skea, G, Strasser, A, Barsukov, I, Lian, L.Y, Huang, D.C, Hinds, M.G.
登録日2003-11-06
公開日2004-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.
Biochem.J., 377, 2004
1ZW3
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BU of 1zw3 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652
分子名称: Talin 1, Vinculin
著者Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
登録日2005-06-03
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005

 

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