1QJS
 
 | | mammalian blood serum haemopexin glycosylated-native protein and in complex with its ligand haem | | 分子名称: | CHLORIDE ION, HEMOPEXIN, PHOSPHATE ION, ... | | 著者 | Paoli, M, Baker, H.M, Morgan, W.T, Smith, A, Baker, E.N. | | 登録日 | 1999-07-01 | | 公開日 | 2000-02-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of Hemopexin Reveals a Novel High-Affinity Heme Site Formed between Two Beta-Propeller Domains.
Nat.Struct.Biol., 6, 1999
|
|
1TY2
 | | Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J) | | 分子名称: | ZINC ION, putative exotoxin (superantigen) | | 著者 | Baker, H.M, Proft, T, Webb, P.D, Arcus, V.L, Fraser, J.D, Baker, E.N. | | 登録日 | 2004-07-07 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization
J.Biol.Chem., 279, 2004
|
|
1TY0
 | | Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J) | | 分子名称: | putative exotoxin (superantigen) | | 著者 | Baker, H.M, Proft, T, Webb, P.D, Arcus, V.L, Fraser, J.D, Baker, E.N. | | 登録日 | 2004-07-06 | | 公開日 | 2004-08-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization
J.Biol.Chem., 279, 2004
|
|
1LCT
 | |
1BSY
 | | STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 7.1 | | 分子名称: | BETA-LACTOGLOBULIN | | 著者 | Qin, B.Y, Bewley, M.C, Creamer, L.K, Baker, E.N, Jameson, G.B. | | 登録日 | 1998-08-31 | | 公開日 | 1999-01-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structural basis of the Tanford transition of bovine beta-lactoglobulin.
Biochemistry, 37, 1998
|
|
1AN8
 | |
5E5T
 | | Quasi-racemic snakin-1 in P1 after radiation damage | | 分子名称: | 1,2-ETHANEDIOL, D- snakin-1, FORMIC ACID, ... | | 著者 | Yeung, H, Squire, C.J, Yosaatmadja, Y, Panjikar, S, Baker, E.N, Harris, P.W.R, Brimble, M.A. | | 登録日 | 2015-10-09 | | 公開日 | 2016-05-18 | | 最終更新日 | 2016-07-20 | | 実験手法 | X-RAY DIFFRACTION (1.572 Å) | | 主引用文献 | Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5E5Q
 | | Racemic snakin-1 in P21/c | | 分子名称: | Snakin-1 | | 著者 | Yeung, H, Squire, C.J, Yosaatmadja, Y, Panjikar, S, Baker, E.N, Harris, P.W.R, Brimble, M.A. | | 登録日 | 2015-10-09 | | 公開日 | 2016-05-18 | | 最終更新日 | 2016-07-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5E5Y
 | | Quasi-racemic snakin-1 in P1 before radiation damage | | 分子名称: | 1,2-ETHANEDIOL, D- snakin-1, FORMIC ACID, ... | | 著者 | Yeung, H, Squire, C.J, Yosaatmadja, Y, Panjikar, S, Baker, E.N, Harris, P.W.R, Brimble, M.A. | | 登録日 | 2015-10-09 | | 公開日 | 2016-05-18 | | 最終更新日 | 2016-07-20 | | 実験手法 | X-RAY DIFFRACTION (1.506 Å) | | 主引用文献 | Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
2O7V
 | | Carboxylesterase AeCXE1 from Actinidia eriantha covalently inhibited by paraoxon | | 分子名称: | CXE carboxylesterase, DIETHYL PHOSPHONATE | | 著者 | Ileperuma, N.R, Marshall, S.D, Squire, C.J, Baker, H.M, Oakeshott, J.G, Russell, R.J, Plummer, K.M, Newcomb, R.D, Baker, E.N. | | 登録日 | 2006-12-11 | | 公開日 | 2007-02-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon.
Biochemistry, 46, 2007
|
|
2O7U
 | | Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N. | | 登録日 | 2006-12-11 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
5FCC
 | | Structure of HutD from Pseudomonas fluorescens SBW25 (NaCl condition) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, HutD, ... | | 著者 | Johnston, J.M, Gerth, M.L, Baker, E.N, Lott, J.S, Rainey, P.B. | | 登録日 | 2015-12-15 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structure of HutD from Pseudomonas fluorescens
To Be Published
|
|
2O84
 | | Crystal structure of K206E mutant of N-lobe human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | | 著者 | Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N. | | 登録日 | 2006-12-12 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2O7R
 | | Plant carboxylesterase AeCXE1 from Actinidia eriantha with acyl adduct | | 分子名称: | CXE carboxylesterase, PROPYL ACETATE | | 著者 | Ileperuma, N.R, Marshall, S.D, Squire, C.J, Baker, H.M, Oakeshott, J.G, Russell, R.J, Plummer, K.M, Newcomb, R.D, Baker, E.N. | | 登録日 | 2006-12-11 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon.
Biochemistry, 46, 2007
|
|
3VEH
 | | Structure of a M. tuberculosis salicylate synthase, MbtI, in complex with an inhibitor methylAMT | | 分子名称: | 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Bulloch, E.M, Chi, G, Manos-Turvey, A, Johnston, J.M, Baker, E.N, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2012-01-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis.
Biochemistry, 51, 2012
|
|
3ZZM
 | | Crystal structure of Mycobacterium tuberculosis PurH with a novel bound nucleotide CFAIR, at 2.2 A resolution. | | 分子名称: | 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, GLYCEROL, ... | | 著者 | Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N. | | 登録日 | 2011-09-02 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.
J.Biol.Chem., 286, 2011
|
|
2FYF
 | | Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis | | 分子名称: | GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ... | | 著者 | Coulibaly, F, Lassalle, E, Baker, E.N, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | 登録日 | 2006-02-07 | | 公開日 | 2007-01-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
|
|
4A1O
 | | Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution. | | 分子名称: | 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, ... | | 著者 | Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N. | | 登録日 | 2011-09-17 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.
J.Biol.Chem., 286, 2011
|
|
4G0S
 | |
1JC4
 | | Crystal Structure of Se-Met Methylmalonyl-CoA Epimerase | | 分子名称: | Methylmalonyl-CoA epimerase, SULFATE ION | | 著者 | Mc Carthy, A.A, Baker, H.M, Shewry, S.C, Patchett, M.L, Baker, E.N. | | 登録日 | 2001-06-07 | | 公開日 | 2001-07-11 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold.
Structure, 9, 2001
|
|
1JC5
 | | Crystal Structure of Native Methylmalonyl-CoA Epimerase | | 分子名称: | Methylmalonyl-CoA Epimerase, SULFATE ION | | 著者 | Mc Carthy, A.A, Baker, H.M, Shewry, S.C, Patchett, M.L, Baker, E.N. | | 登録日 | 2001-06-07 | | 公開日 | 2001-07-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold.
Structure, 9, 2001
|
|
2IO6
 | | Wee1 kinase complexed with inhibitor PD330961 | | 分子名称: | 9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, Wee1-like protein kinase | | 著者 | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | | 登録日 | 2006-10-10 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
Eur.J.Med.Chem., 43, 2008
|
|
2IN6
 | | Wee1 kinase complex with inhibitor PD311839 | | 分子名称: | 3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID, Wee1-like protein kinase | | 著者 | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | | 登録日 | 2006-10-05 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
Eur.J.Med.Chem., 43, 2008
|
|
2CEV
 | | ARGINASE FROM BACILLUS CALDEVELOX, NATIVE STRUCTURE AT PH 8.5 | | 分子名称: | GUANIDINE, MANGANESE (II) ION, PROTEIN (ARGINASE) | | 著者 | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | | 登録日 | 1999-03-10 | | 公開日 | 1999-04-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
|
|
2BPQ
 | | Anthranilate phosphoribosyltransferase (TrpD) from Mycobacterium tuberculosis (Apo structure) | | 分子名称: | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, BENZAMIDINE, GLYCEROL | | 著者 | Lee, C.E, Goodfellow, C, Javid-Majd, F, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2005-04-22 | | 公開日 | 2006-01-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of Trpd, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium Tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate
J.Mol.Biol., 355, 2006
|
|
