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PDB: 18 件
3RI4
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BU of 3ri4 by Molmil
Ets1 cooperative binding to widely separated sites on promoter DNA
分子名称: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA
著者Babayeva, N.D, Mino, K, Tahirov, T.H.
登録日2011-04-12
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
Plos One, 7, 2012
3MFK
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BU of 3mfk by Molmil
Ets1 complex with stromelysin-1 promoter DNA
分子名称: Protein C-ets-1, stromelysin-1 promoter DNA
著者Babayeva, N.D, Mino, K, Tahirov, T.H.
登録日2010-04-02
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA.
Cell Cycle, 9, 2010
3E0J
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BU of 3e0j by Molmil
X-ray structure of the complex of regulatory subunits of human DNA polymerase delta
分子名称: DNA polymerase subunit delta-2, DNA polymerase subunit delta-3
著者Baranovskiy, A.G, Babayeva, N.D, Pavlov, Y.I, Vassylyev, D.G, Tahirov, T.H.
登録日2008-07-31
公開日2008-12-16
最終更新日2020-10-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of the complex of regulatory subunits of human DNA polymerase delta.
Cell Cycle, 7, 2008
4RR2
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BU of 4rr2 by Molmil
Crystal structure of human primase
分子名称: DNA primase large subunit, DNA primase small subunit, IRON/SULFUR CLUSTER, ...
著者Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H.
登録日2014-11-05
公開日2015-01-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the human primase.
J.Biol.Chem., 290, 2015
5VBN
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BU of 5vbn by Molmil
Crystal Structure of human DNA polymerase epsilon B-subunit in complex with C-terminal domain of catalytic subunit
分子名称: DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit 2, SULFATE ION, ...
著者Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H.
登録日2017-03-29
公開日2017-08-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of the human Pol B-subunit in complex with the C-terminal domain of the catalytic subunit.
J. Biol. Chem., 292, 2017
7N2M
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BU of 7n2m by Molmil
Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*T*AP*GP*TP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), DNA polymerase alpha catalytic subunit, ...
著者Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
登録日2021-05-29
公開日2022-04-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional insight into mismatch extension by human DNA polymerase alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
6AS7
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BU of 6as7 by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ...
著者Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
登録日2017-08-23
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Activity and fidelity of human DNA polymerase alpha depend on primer structure.
J. Biol. Chem., 293, 2018
4Y97
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Crystal Structure of human Pol alpha B-subunit in complex with C-terminal domain of catalytic subunit
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ZINC ION
著者Suwa, Y, Gu, J, Baranovskiy, A.G, Babayeva, N.D, Tahirov, T.H.
登録日2015-02-17
公開日2015-04-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal Structure of the Human Pol alpha B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit.
J.Biol.Chem., 290, 2015
3JTG
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BU of 3jtg by Molmil
Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA
分子名称: DNA (5'-D(*CP*AP*AP*AP*CP*AP*GP*GP*AP*AP*AP*CP*TP*CP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*GP*TP*TP*TP*CP*CP*TP*GP*TP*TP*T)-3'), ETS-related transcription factor Elf-3
著者Tahirov, T.H, Babayeva, N.D, Agarkar, V.B, Rizzino, A.
登録日2009-09-11
公開日2010-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA.
J.Mol.Biol., 397, 2010
5EXR
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BU of 5exr by Molmil
Crystal structure of human primosome
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
著者Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
登録日2015-11-24
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
5F0S
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BU of 5f0s by Molmil
Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion
分子名称: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ...
著者Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
登録日2015-11-28
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
5F0Q
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BU of 5f0q by Molmil
Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer
分子名称: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ...
著者Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
登録日2015-11-28
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
4QCL
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BU of 4qcl by Molmil
Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA TEMPLATE, ...
著者Baranovskiy, A.G, Suwa, Y, Babayeva, N.D, Gu, J, Tahirov, T.H.
登録日2014-05-12
公開日2014-11-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Activity and fidelity of human DNA polymerase alpha depend on primer structure
J.Biol.Chem., 2018
4Q5V
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BU of 4q5v by Molmil
Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin
分子名称: (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthale ne-3,9-diol, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Baranovskiy, A.G, Babayeva, N.D, Suwa, Y, Gu, J, Tahirov, T.H.
登録日2014-04-17
公開日2014-11-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural basis for inhibition of DNA replication by aphidicolin.
Nucleic Acids Res., 42, 2014
4OR5
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BU of 4or5 by Molmil
Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4
分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ...
著者Gu, J, Babayeva, N.D, Suwa, Y, Baranovskiy, A.G, Price, D.H, Tahirov, T.H.
登録日2014-02-10
公開日2014-04-16
最終更新日2014-06-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.
Cell Cycle, 13, 2014
3Q36
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BU of 3q36 by Molmil
Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit
分子名称: DNA primase large subunit, FE (III) ION, IRON/SULFUR CLUSTER
著者Agarkar, V.B, Babayeva, N.D, Tahirov, T.H.
登録日2010-12-21
公開日2011-04-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch.
Cell Cycle, 10, 2011
3MI9
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BU of 3mi9 by Molmil
Crystal structure of HIV-1 Tat complexed with human P-TEFb
分子名称: Cell division protein kinase 9, Cyclin-T1, Protein Tat, ...
著者Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H.
登録日2010-04-09
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of HIV-1 Tat complexed with human P-TEFb.
Nature, 465, 2010
3MIA
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BU of 3mia by Molmil
Crystal structure of HIV-1 Tat complexed with ATP-bound human P-TEFb
分子名称: Cell division protein kinase 9, Cyclin-T1, MAGNESIUM ION, ...
著者Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H.
登録日2010-04-09
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of HIV-1 Tat complexed with human P-TEFb.
Nature, 465, 2010

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