1K9L
 
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1TVD
 | | VARIABLE DOMAIN OF T CELL RECEPTOR DELTA CHAIN | | Descriptor: | T CELL RECEPTOR | | Authors: | Li, H.M, Lebedeva, M.I, Llera, A.S, Fields, B.A, Brenner, M.B, Mariuzza, R.A. | | Deposit date: | 1997-10-19 | | Release date: | 1998-04-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor.
Nature, 391, 1998
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1U2H
 | | X-ray Structure of the N-terminally truncated human APEP-1 | | Descriptor: | Aortic preferentially expressed protein 1 | | Authors: | Manjasetty, B.A, Scheich, C, Roske, Y, Niesen, F.H, Gotz, F, Bussow, K, Heinemann, U. | | Deposit date: | 2004-07-19 | | Release date: | 2005-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (0.96 Å) | | Cite: | X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)
Bmc Struct.Biol., 5, 2005
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1U20
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1KFZ
 | | Solution Structure of C-terminal Sem-5 SH3 Domain (Ensemble of 16 Structures) | | Descriptor: | SEX MUSCLE ABNORMAL PROTEIN 5 | | Authors: | Ferreon, J.C, Volk, D.E, Luxon, B.A, Gorenstein, D, Hilser, V.J. | | Deposit date: | 2001-11-24 | | Release date: | 2003-05-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble
of Sem-5 C-Terminal SH3 Domain
Biochemistry, 42, 2003
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1U68
 | | DHNA 7,8 DIHYDRONEOPTERIN COMPLEX | | Descriptor: | 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, Dihydroneopterin aldolase | | Authors: | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | | Deposit date: | 2004-07-29 | | Release date: | 2004-10-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.
J.MED.CHEM., 47, 2004
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1KIR
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1U3O
 | | Solution structure of rat Kalirin N-terminal SH3 domain | | Descriptor: | Huntingtin-associated protein-interacting protein | | Authors: | Schiller, M.R, Chakrabarti, K, King, G.F, Schiller, N.I, Eipper, B.A, Maciejewski, M.W. | | Deposit date: | 2004-07-22 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions.
J.Biol.Chem., 281, 2006
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1TX9
 | | gpd prior to capsid assembly | | Descriptor: | Scaffolding protein D | | Authors: | Morais, M.C, Fisher, M, Kanamaru, K, Fane, B.A, Rossmann, M.G. | | Deposit date: | 2004-06-24 | | Release date: | 2005-04-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | Conformational switching by the scaffolding protein D directs the assembly of bacteriophage phiX174
Mol.Cell, 15, 2004
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1GQ0
 | | Solution structure of Antiamoebin I, a membrane channel-forming polypeptide; NMR, 20 structures | | Descriptor: | ANTIAMOEBIN I | | Authors: | Galbraith, T.P, Harris, R, Driscoll, P.C, Wallace, B.A. | | Deposit date: | 2001-11-16 | | Release date: | 2003-01-24 | | Last modified: | 2017-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution NMR studies of antiamoebin, a membrane channel-forming polypeptide.
Biophys. J., 84, 2003
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1GJ4
 | | SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN | | Descriptor: | 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE, ACETYL HIRUDIN, SODIUM ION, ... | | Authors: | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | Deposit date: | 2001-04-27 | | Release date: | 2002-04-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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1GJ5
 | | SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN | | Descriptor: | 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, ACETYL HIRUDIN, SODIUM ION, ... | | Authors: | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | Deposit date: | 2001-04-27 | | Release date: | 2002-04-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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1GMK
 | | GRAMICIDIN/KSCN COMPLEX | | Descriptor: | GRAMICIDIN A, METHANOL, POTASSIUM ION, ... | | Authors: | Doyle, D.A, Wallace, B.A. | | Deposit date: | 1996-07-09 | | Release date: | 1998-07-01 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the Gramicidin/Potassium Thiocyanate Complex.
J.Mol.Biol., 266, 1997
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1JCK
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5J53
 | | The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase | | Descriptor: | Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ... | | Authors: | McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D. | | Deposit date: | 2016-04-01 | | Release date: | 2016-11-30 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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2PFE
 | | Crystal Structure of Thermobifida fusca Protease A (TFPA) | | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Alkaline serine protease, GLYCEROL, ... | | Authors: | Kelch, B.A, Agard, D.A. | | Deposit date: | 2007-04-04 | | Release date: | 2007-07-03 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.436 Å) | | Cite: | Mesophile versus Thermophile: Insights Into the Structural Mechanisms of Kinetic Stability
J.Mol.Biol., 370, 2007
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8EBM
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8EBN
 | | Structure of KLHDC2-EloB/C tetrameric assembly | | Descriptor: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | | Authors: | Scott, D.C, Schulman, B.A. | | Deposit date: | 2022-08-31 | | Release date: | 2023-02-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
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8EBL
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2PFV
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2PFT
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7A8Y
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2QQO
 | | Crystal Structure of the a2b1b2 Domains from Human Neuropilin-2 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | Authors: | Appleton, B.A, Wiesmann, C. | | Deposit date: | 2007-07-26 | | Release date: | 2007-11-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
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8EHO
 | | PRRSV-1 PLP2 domain bound to ubiquitin | | Descriptor: | 3-AMINOPROPANE, GLYCEROL, NITRATE ION, ... | | Authors: | Bailey-Elkin, B.A, Mark, B.L. | | Deposit date: | 2022-09-14 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Plos Pathog., 19, 2023
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8EHN
 | | PRRSV-1 PLP2 domain | | Descriptor: | ACETATE ION, Papain-like protease 2, ZINC ION | | Authors: | Bailey-Elkin, B.A, Mark, B.L. | | Deposit date: | 2022-09-14 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Plos Pathog., 19, 2023
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