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PDB: 1208 results

1BC3
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RECOMBINANT RAT ANNEXIN V, TRIPLE MUTANT (T72K, S144K, S228K)
Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION
Authors:Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A.
Deposit date:1998-05-04
Release date:1998-11-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
Biochemistry, 37, 1998
2ISO
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BU of 2iso by Molmil
Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate
Descriptor: 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A.
Deposit date:2006-10-18
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta.
Biochemistry, 46, 2007
3AX4
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BU of 3ax4 by Molmil
Three-dimensional structure of lectin from Dioclea violacea and comparative vasorelaxant effects with Dioclea rostrata
Descriptor: 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, MANGANESE (II) ION, ...
Authors:Bezerra, M.J.B, Bezerra, G.A, Martins, J.L, Nascimento, K.S, Nagano, C.S, Gruber, K, Assereuy, A.M, Delatorre, P, Rocha, B.A.M, Cavada, B.S.
Deposit date:2011-03-29
Release date:2012-04-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.613 Å)
Cite:Crystal structure of Dioclea violacea lectin and a comparative study of vasorelaxant properties with Dioclea rostrata lectin
Int.J.Biochem.Cell Biol., 45, 2013
1M0E
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ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE
Descriptor: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ...
Authors:Zhou, L, Cheng, X, Connolly, B.A, Dickman, M.J, Hurd, P.J, Hornby, D.P.
Deposit date:2002-06-12
Release date:2002-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
J.MOL.BIOL., 321, 2002
6TTU
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BU of 6ttu by Molmil
Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2
Descriptor: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Prabu, J.R, Schulman, B.A.
Deposit date:2019-12-30
Release date:2020-02-12
Last modified:2020-03-04
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Nature, 578, 2020
1BTX
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Episelection: Novel Ki ~Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface
Descriptor: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1S)-5-amino-1-(diethoxyboranyl)pentyl]-L-valinamide
Authors:Stroud, R.M, Katz, B.A, Finer-Moore, J.
Deposit date:1995-05-17
Release date:1995-10-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1C1T
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BU of 1c1t by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C2L
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RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: CALCIUM ION, CHLORIDE ION, TRYPSIN, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C1Q
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BU of 1c1q by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: (5-AMIDINO-2-BENZIMIDAZOLYL)(2-BENZIMIDAZOLYL)METHANE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1MN3
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BU of 1mn3 by Molmil
Cue domain of yeast Vps9p
Descriptor: Vacuolar protein sorting-associated protein VPS9
Authors:Prag, G, Misra, S, Jones, E, Ghirlando, R, Davies, B.A, Horazdovsky, B.F, Hurley, J.H.
Deposit date:2002-09-04
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p
Cell(Cambridge,Mass.), 113, 2003
1QYM
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BU of 1qym by Molmil
X-ray structure of human gankyrin
Descriptor: 26S proteasome non-ATPase regulatory subunit 10
Authors:Manjasetty, B.A, Quedenau, C, Sievert, V, Buessow, K, Niesen, F, Delbrueck, H, Heinemann, U.
Deposit date:2003-09-11
Release date:2003-11-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.
Proteins, 55, 2004
1C1P
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BU of 1c1p by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: (5-AMIDINO-2-BENZIMIDAZOLYL)(2-BENZIMIDAZOLYL)METHANE, CALCIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C2M
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BU of 1c2m by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: CALCIUM ION, MAGNESIUM ION, SULFATE ION, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
2WHZ
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BU of 2whz by Molmil
Dipeptide Inhibitors of Thermolysin
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, ISOLEUCINE, ...
Authors:Lund, B.A, Leiros, I, Leiros, H.-K.S.
Deposit date:2009-05-07
Release date:2010-05-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dipeptide Inhibitors of Thermolysin
To be Published
1BTY
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BU of 1bty by Molmil
Crystal structure of beta-trypsin in complex with benzamidine
Descriptor: BENZAMIDINE, BETA-TRYPSIN, CALCIUM ION
Authors:Stroud, R.M, Katz, B.A, Finer-Moore, J.
Deposit date:1995-05-17
Release date:1995-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1C2G
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BU of 1c2g by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANE KETONE HYDRATE, CALCIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1MHU
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BU of 1mhu by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF HUMAN [113CD7] METALLOTHIONEIN-2 IN SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: CADMIUM ION, CD7 METALLOTHIONEIN-2
Authors:Braun, W, Messerle, B.A, Schaeffer, A, Vasak, M, Kaegi, J.H.R, Wuthrich, K.
Deposit date:1990-05-14
Release date:1991-04-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional structure of human [113Cd7]metallothionein-2 in solution determined by nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 214, 1990
1BTZ
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Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface
Descriptor: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-{(1R)-5-ammonio-1-[hydroxy(methoxy)boranyl]pentyl}-L-valinamide
Authors:Stroud, R.M, Katz, B.A, Finer-Moore, J.
Deposit date:1995-05-17
Release date:1995-10-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1C1N
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BU of 1c1n by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: BENZAMIDINE, CALCIUM ION, SULFATE ION, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C1W
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BU of 1c1w by Molmil
RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANE KETONE HYDRATE, Hirudin-2, SODIUM ION, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1FS2
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BU of 1fs2 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
3BN6
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BU of 3bn6 by Molmil
Crystal Structure of the C2 Domain of Bovine Lactadherin at 1.67 Angstrom Resolution
Descriptor: Lactadherin
Authors:Shao, C, Novakovic, V.A, Head, J.F, Seaton, B.A, Gilbert, G.E.
Deposit date:2007-12-13
Release date:2007-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.
J.Biol.Chem., 283, 2008
1FP8
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BU of 1fp8 by Molmil
STRUCTURE OF THE AMYLOMALTASE FROM THERMUS THERMOPHILUS HB8 IN SPACE GROUP P21212
Descriptor: 4-ALPHA-GLUCANOTRANSFERASE, CHLORIDE ION, MERCURY (II) ION
Authors:Uitdehaag, J.C.M, Euverink, G.J, van der Veen, B.A, van der Maarel, M, Dijkstra, B.W.
Deposit date:2000-08-31
Release date:2003-09-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanism of the amylomaltase from Thermus thermophilus HB8
To be Published
1M24
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BU of 1m24 by Molmil
Trichotoxin_A50E, An Ion Channel-Forming Polypeptide
Descriptor: ACETONITRILE, TRICHOTOXIN_A50E
Authors:Chugh, J.K, Brueckner, H, Wallace, B.A.
Deposit date:2002-06-21
Release date:2002-11-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Model for a Helical Bundle Channel Based on the High-Resolution Crystal Structure of Trichotoxin_A50E
Biochemistry, 41, 2002
1HMV
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BU of 1hmv by Molmil
THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Descriptor: HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66), MAGNESIUM ION
Authors:Rodgers, D.W, Gamblin, S.J, Harris, B.A, Ray, S, Culp, J.S, Hellmig, B, Woolf, D.J, Debouck, C, Harrison, S.C.
Deposit date:1994-12-15
Release date:1995-03-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.USA, 92, 1995

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