8DOA
 
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9AVA
 | | Co-crystal structure of human TREX1 in complex with an inhibitor | | 分子名称: | (2R)-2-[(5R,6S,8R,9aS)-8-amino-1-oxo-5-(2-phenylethyl)hexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl]-N-[(3,4-dichlorophenyl)methyl]-4-methylpentanamide, POTASSIUM ION, Three-prime repair exonuclease 1, ... | | 著者 | Dehghani-Tafti, S, Dong, A, Li, Y, Xu, J, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2024-03-01 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Co-crystal structure of human TREX1 in complex with an inhibitor
To be published
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1HV2
 | | SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE | | 分子名称: | ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR | | 著者 | Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H. | | 登録日 | 2001-01-05 | | 公開日 | 2001-09-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
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8DYS
 | | Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A) | | 分子名称: | 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2A, GLYCEROL, ... | | 著者 | Righetto, G.L, Zeng, H, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2022-08-05 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A)
To Be Published
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7RAY
 | | Crystal structure of MBD2 with DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*A)-R(P*(5MC))-D(P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION | | 著者 | Liu, K, Dong, A, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2021-07-05 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of MBD2 with DNA
To Be Published
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7RBQ
 | | Co-crystal structure of human PRMT9 in complex with MT556 inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 7-[5-S-(4-{[(4-ethylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Protein arginine N-methyltransferase 9, ... | | 著者 | Zeng, H, Dong, A, Hutchinson, A, Seitova, A, Li, Y, Gao, Y.D, Schneider, S, Siliphaivanh, P, Sloman, D, Nicholson, B, Fischer, C, Hicks, J, Brown, P.J, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2021-07-06 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Co-crystal structure of human PRMT9 in complex with MT556 inhibitor
To Be Published
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1HS5
 | | NMR SOLUTION STRUCTURE OF DESIGNED P53 DIMER | | 分子名称: | CELLULAR TUMOR ANTIGEN P53 | | 著者 | Davison, T.S, Nie, X, Ma, W, Li, Y, Kay, C, Benchimol, S, Arrowsmith, C.H. | | 登録日 | 2000-12-22 | | 公開日 | 2001-01-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and functionality of a designed p53 dimer.
J.Mol.Biol., 307, 2001
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7YXX
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7YXY
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4UY4
 | | 1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide | | 分子名称: | GLYCEROL, HISTONE H3K4ME3, SPINDLIN-4 | | 著者 | Talon, R, Gileadi, C, Johansson, C, Burgess-Brown, N, Shrestha, L, von Delft, F, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U. | | 登録日 | 2014-08-28 | | 公開日 | 2014-09-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.862 Å) | | 主引用文献 | 1.86 A Structure of Human Spindlin-4 Protein in Complex with Histone H3K4Me3 Peptide
To be Published
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7UGC
 | | Structure of the N-terminal domain of ViaA | | 分子名称: | Protein ViaA | | 著者 | Lemak, A, Reichheld, S, Bhandari, V, Houliston, S, Arrowsmith, C.H, Sharpe, S, Houry, W.A. | | 登録日 | 2022-03-24 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the N-terminal domain of ViaA
To Be Published
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7T2F
 | | Solution structure of the model HEEH mini protein homodimer HEEH_TK_rd5_0341 | | 分子名称: | HEEH mini protein HEEH_TK_rd5_0341 | | 著者 | Lemak, A, Houliston, S, Kim, T.-E, Martel, C, Rocklin, G.J, Arrowsmith, C.H. | | 登録日 | 2021-12-04 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8PTT
 | | Human NUDT5 in complex with MRK-952 | | 分子名称: | 6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine, ADP-sugar pyrophosphatase, MAGNESIUM ION | | 著者 | Diaz-Saez, L, Koekemoer, L, Feyerherm, C, Sloman, S, Fischer, C, Schneider, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K.V.M. | | 登録日 | 2023-07-14 | | 公開日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Human NUDT5 in complex with MRK-952
To Be Published
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3KFV
 | | Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in apo-form | | 分子名称: | Tight junction protein ZO-3, UNKNOWN ATOM OR ION | | 著者 | Tong, Y, Nedyalkova, L, Tempel, W, Zhong, N, Guan, X, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-10-28 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in apo-form
to be published
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3KVG
 | | Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP | | 分子名称: | 1,2-ETHANEDIOL, Heat shock 70 (HSP70) protein, PHOSPHATE ION, ... | | 著者 | Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-30 | | 公開日 | 2010-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP
To be Published
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3L43
 | | Crystal structure of the dynamin 3 GTPase domain bound with GDP | | 分子名称: | Dynamin-3, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION | | 著者 | Yang, S, Tempel, W, Tong, Y, Nedyalkova, L, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-12-18 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structure of the dynamin 3 GTPase domain bound with GDP
to be published
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3KHD
 | | Crystal Structure of PFF1300w. | | 分子名称: | Pyruvate kinase | | 著者 | Wernimont, A.K, Hutchinson, A, Hassanali, A, Mackenzie, F, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J.C, Bakszt, R, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2009-10-30 | | 公開日 | 2010-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of PFF1300w.
To be Published
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3KUP
 | | Crystal Structure of the CBX3 Chromo Shadow Domain | | 分子名称: | Chromobox protein homolog 3, UNKNOWN ATOM OR ION | | 著者 | Tempel, W, Li, Z, Li, Y, Kozieradzki, I, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-27 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal Structure of the CBX3 Chromo Shadow Domain
to be published
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3KUL
 | | Kinase domain of human ephrin type-A receptor 8 (EPHA8) | | 分子名称: | BETA-MERCAPTOETHANOL, Ephrin type-A receptor 8, GLYCEROL, ... | | 著者 | Walker, J.R, Yermekbayeva, L, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-27 | | 公開日 | 2009-12-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Kinase Domain of Human Ephrin Type-A Receptor 8 (Epha8)
To be Published
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3L19
 | | Crystal structure of calcium binding domain of CpCDPK3, cgd5_820 | | 分子名称: | CALCIUM ION, Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, GLYCEROL, ... | | 著者 | Qiu, W, Hutchinson, A, Wernimont, A, Walker, J.R, Sullivan, H, Lin, Y.-H, Mackenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | | 登録日 | 2009-12-11 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Crystal structure of calcium binding domain of CpCDPK3, cgd5_820
To be Published
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3L46
 | | Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2) | | 分子名称: | Protein ECT2, UNKNOWN ATOM OR ION | | 著者 | Nedyalkova, L, Tempel, W, Tong, Y, Crombet, L, Wang, H, Guan, X, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-12-18 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.482 Å) | | 主引用文献 | Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)
to be published
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3KUZ
 | | Crystal structure of the ubiquitin like domain of PLXNC1 | | 分子名称: | Plexin-C1, UNKNOWN ATOM OR ION | | 著者 | Wang, H, Li, B, Tempel, W, Tong, Y, Guan, X, Zhong, N, Crombet, L, MacKenzie, F, Buck, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-28 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the ubiquitin like domain of PLXNC1
to be published
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3KVH
 | | Crystal structure of human protein syndesmos (NUDT16-like protein) | | 分子名称: | CHLORIDE ION, GLYCEROL, Protein syndesmos | | 著者 | Tresaugues, L, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Kotzsch, A, Kraulis, P, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Roos, A.K, Schuler, H, Schutz, P, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-30 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of human protein syndesmos (NUDT16L1)
To be Published
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3LIJ
 | | Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP | | 分子名称: | CALCIUM ION, Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, MAGNESIUM ION, ... | | 著者 | Qiu, W, Hutchinson, A, Wernimont, A, Walker, J.R, Sullivan, H, Lin, Y.-H, Mackenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-01-25 | | 公開日 | 2010-02-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP
To be Published
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3LLT
 | | Crystal structure of PF14_0431, kinase domain. | | 分子名称: | ACETATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | | 著者 | Wernimont, A.K, Tempel, W, Lin, Y.H, Loppnau, P, MacKenzie, F, Sullivan, H, Weadge, J, Kozieradzki, I, Cossar, D, Sinesterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Qiu, W, Hutchinson, A, Structural Genomics Consortium (SGC) | | 登録日 | 2010-01-29 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of PF14_0431, kinase domain.
TO BE PUBLISHED
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