8PTT

Human NUDT5 in complex with MRK-952

This is a non-PDB format compatible entry.

Summary for 8PTT

• Entry DOI: 10.2210/pdb8ptt/pdb
• Descriptor: ADP-sugar pyrophosphatase, 6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 99339.96

Authors

Diaz-Saez, L.,Koekemoer, L.,Feyerherm, C.,Sloman, S.,Fischer, C.,Schneider, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.V.M. (deposition date: 2023-07-14, release date: 2024-07-24)

• Primary citation: Diaz-Saez, L.,Koekemoer, L.,Feyerherm, C.,Sloman, S.,Fischer, C.,Schneider, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.V.M.; Human NUDT5 in complex with MRK-952; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)