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8PTT

Human NUDT5 in complex with MRK-952

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ADP-sugar pyrophosphatasepolymer21924355.64UniProt (Q9UKK9)
Pfam (PF00293)
Homo sapiens (human)8-oxo-dGDP phosphatase,Nuclear ATP-synthesis protein NUDIX5,Nucleoside diphosphate-linked moiety X motif 5,hNUDT5,YSA1H
2E, G, K, N
(A, B, C, D)
6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purinenon-polymer436.94Chemie (F2V)
3F, H, I, J, L...
(A, B, C, D)
MAGNESIUM IONnon-polymer24.37Chemie (MG)
4P, Q, R, S
(A, B, C, D)
waterwater18.0290Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight97422.4
Non-Polymers*Number of molecules11
Total formula weight1917.6
All*Total formula weight99340.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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