Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 54 results

4I5U
DownloadVisualize
BU of 4i5u by Molmil
Crystal structure of a fungal chimeric cellobiohydrolase Cel6A
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Chimeric cel6A, ...
Authors:Arnold, F.H, Wu, I.
Deposit date:2012-11-29
Release date:2013-04-03
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures.
Biotechnol.Bioeng., 110, 2013
4I5R
DownloadVisualize
BU of 4i5r by Molmil
Crystal structure of a fungal chimeric cellobiohydrolase Cel6A
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Chimeric cel6A, ...
Authors:Arnold, F.H, Wu, I.
Deposit date:2012-11-28
Release date:2013-04-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures.
Biotechnol.Bioeng., 110, 2013
8VHH
DownloadVisualize
BU of 8vhh by Molmil
Engineered holo tryptophan synthase (Tm9D8*) derived from T. maritima TrpB
Descriptor: PHOSPHATE ION, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Porter, N.J, Johnston, K.E, Almhjell, P.J, Arnold, F.H.
Deposit date:2024-01-02
Release date:2024-08-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A combinatorially complete epistatic fitness landscape in an enzyme active site.
Proc.Natl.Acad.Sci.USA, 121, 2024
4DUC
DownloadVisualize
BU of 4duc by Molmil
cytochrome P450 BM3h-2G9 MRI sensor, no ligand
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 2G9
Authors:Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H.
Deposit date:2012-02-21
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin.
J.Mol.Biol., 422, 2012
4DTW
DownloadVisualize
BU of 4dtw by Molmil
cytochrome P450 BM3h-8C8 MRI sensor bound to serotonin
Descriptor: Cytochrome P450 BM3 variant 8C8, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H.
Deposit date:2012-02-21
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin.
J.Mol.Biol., 422, 2012
4DUA
DownloadVisualize
BU of 4dua by Molmil
cytochrome P450 BM3h-9D7 MRI sensor, no ligand
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL, cytochrome P450 BM3 variant 9D7
Authors:Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H.
Deposit date:2012-02-21
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin.
J.Mol.Biol., 422, 2012
4EEZ
DownloadVisualize
BU of 4eez by Molmil
Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase variant RE1
Descriptor: Alcohol dehydrogenase 1, TETRAETHYLENE GLYCOL, ZINC ION
Authors:Liu, X, Bastian, S, Snow, C.D, Brustad, E.M, Saleski, T, Xu, J.H, Meinhold, P, Arnold, F.H.
Deposit date:2012-03-28
Release date:2012-09-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.
J.Biotechnol., 164, 2012
4XDY
DownloadVisualize
BU of 4xdy by Molmil
Structure of NADH-preferring ketol-acid reductoisomerase from an uncultured archean
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, Ketol-acid reductoisomerase, ...
Authors:Cahn, J.K.B, Brinkmann-Chen, S, Arnold, F.H.
Deposit date:2014-12-20
Release date:2015-04-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.535 Å)
Cite:Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Biochem.J., 468, 2015
4XDZ
DownloadVisualize
BU of 4xdz by Molmil
Holo structure of ketol-acid reductoisomerase from Ignisphaera aggregans
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ketol-acid reductoisomerase, ...
Authors:Cahn, J.K.B, Brinkmann-Chen, S, Arnold, F.H.
Deposit date:2014-12-20
Release date:2015-04-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Biochem.J., 468, 2015
4XEH
DownloadVisualize
BU of 4xeh by Molmil
Apo structure of KARI from Ignisphaera aggregans
Descriptor: Ketol-acid reductoisomerase
Authors:Cahn, J.K.B, Brinkmann-Chen, S, Arnold, F.H.
Deposit date:2014-12-23
Release date:2015-04-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.391 Å)
Cite:Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Biochem.J., 468, 2015
8EGY
DownloadVisualize
BU of 8egy by Molmil
Engineered holo tyrosine synthase (TmTyrS1) derived from T. maritima TrpB
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
8EH1
DownloadVisualize
BU of 8eh1 by Molmil
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline
Descriptor: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Engineered tyrosine synthase (TmTyrS1), POTASSIUM ION, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
8EH0
DownloadVisualize
BU of 8eh0 by Molmil
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with quinoline N-oxide
Descriptor: 1,2-ETHANEDIOL, 1-oxo-1lambda~5~-quinoline, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
8EGZ
DownloadVisualize
BU of 8egz by Molmil
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate
Descriptor: 1,2-ETHANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, POTASSIUM ION, ...
Authors:Porter, N.J, Almhjell, P.J, Arnold, F.H.
Deposit date:2022-09-13
Release date:2023-10-04
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
4TPN
DownloadVisualize
BU of 4tpn by Molmil
High-resolution structure of TxtE in the absence of substrate
Descriptor: GLYCEROL, LITHIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Cahn, J.K.B, Dodani, S.C, Brinkmann-Chen, S, Heinsich, T, McIntosh, J.A, Arnold, F.H.
Deposit date:2014-06-08
Release date:2014-09-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE.
Chembiochem, 15, 2014
4TPO
DownloadVisualize
BU of 4tpo by Molmil
High-resolution structure of TxtE with bound tryptophan substrate
Descriptor: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like protein, ...
Authors:Cahn, J.K.B, Dodani, S.C, Brinkmann-Chen, S, Heinsich, T, McIntosh, J.A, Arnold, F.H.
Deposit date:2014-06-08
Release date:2014-09-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.225 Å)
Cite:Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE.
Chembiochem, 15, 2014
4TSK
DownloadVisualize
BU of 4tsk by Molmil
Ketol-acid reductoisomerase from Alicyclobacillus acidocaldarius
Descriptor: Ketol-acid reductoisomerase, L(+)-TARTARIC ACID, MAGNESIUM ION, ...
Authors:Cahn, J.K.B, Brinkmann-Chen, S, Arnold, F.H.
Deposit date:2014-06-18
Release date:2014-07-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Uncovering rare NADH-preferring ketol-acid reductoisomerases.
Metab. Eng., 26C, 2014
4WG2
DownloadVisualize
BU of 4wg2 by Molmil
P411BM3-CIS T438S I263F regioselective C-H amination catalyst
Descriptor: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Hyster, T.K, Farwell, C.C, Buller, A.R, McIntosh, J.A, Arnold, F.H.
Deposit date:2014-09-17
Release date:2014-11-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-h amination.
J.Am.Chem.Soc., 136, 2014
4XIY
DownloadVisualize
BU of 4xiy by Molmil
Crystal structure of ketol-acid reductoisomerase from Azotobacter
Descriptor: DI(HYDROXYETHYL)ETHER, FE (III) ION, Ketol-acid reductoisomerase, ...
Authors:Spatzal, T, Cahn, J.K.B, Wiig, J.A, Einsle, O, Hu, Y, Ribbe, M.W, Arnold, F.H.
Deposit date:2015-01-07
Release date:2015-04-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Biochem.J., 468, 2015
5IXJ
DownloadVisualize
BU of 5ixj by Molmil
Tryptophan Synthase beta-subunit from Pyrococcus furiosus with L-threonine non-covalently bound in the active site
Descriptor: SODIUM ION, THREONINE, Tryptophan synthase beta chain 1
Authors:Buller, A.R, Herger, M, Arnold, F.H.
Deposit date:2016-03-23
Release date:2016-08-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Synthesis of beta-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase.
J.Am.Chem.Soc., 138, 2016
6WK3
DownloadVisualize
BU of 6wk3 by Molmil
Engineered carbene transferase RmaNOD Q52V, putative nitric oxide dioxygenase from Rhodothermus marinus
Descriptor: ACETATE ION, COPPER (II) ION, Nitric oxide dioxygenase, ...
Authors:Knight, A.M, Arnold, F.H.
Deposit date:2020-04-15
Release date:2020-07-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Diversity-Oriented Enzymatic Synthesis of Cyclopropane Building Blocks.
Acs Catalysis, 10, 2020
3QI8
DownloadVisualize
BU of 3qi8 by Molmil
Evolved variant of cytochrome P450 (BM3, CYP102A1)
Descriptor: Evolved Cytochrome P450 variant (22A3), PROTOPORPHYRIN IX CONTAINING FE
Authors:Rentmeister, A, Brown, T.R, Snow, C.D, Carbone, M.N, Arnold, F.H.
Deposit date:2011-01-26
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Engineered Bacterial Mimics of Human Drug Metabolizing Enzyme CYP2C9
Chemcatchem, 2011
8DSG
DownloadVisualize
BU of 8dsg by Molmil
P411-PFA carbene transferase
Descriptor: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450-BM3 variant P411-PFA, ...
Authors:Maggiolo, A.O, Porter, N.J, Zhang, J, Arnold, F.H.
Deposit date:2022-07-22
Release date:2023-03-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Chemodivergent C(sp 3 )-H and C(sp 2 )-H Cyanomethylation Using Engineered Carbene Transferases.
Nat Catal, 6, 2023
5T6M
DownloadVisualize
BU of 5t6m by Molmil
Structure of the tryptophan synthase b-subunit from Pyroccus furiosus with b-methyltryptophan non-covalently bound
Descriptor: (betaS)-beta-methyl-L-tryptophan, PHOSPHATE ION, SODIUM ION, ...
Authors:Buller, A.R, van Roye, P, Arnold, F.H.
Deposit date:2016-09-01
Release date:2016-12-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity.
Biochemistry, 55, 2016
5UCW
DownloadVisualize
BU of 5ucw by Molmil
Cytochrome P411 P-4 A82L A78V F263L amination catalyst
Descriptor: NADPH-cytochrome P450 reductase 102A1V3, PROTOPORPHYRIN IX CONTAINING FE
Authors:Zhang, R.K, Buller, A.R, Arnold, F.H.
Deposit date:2016-12-22
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enantioselective, intermolecular benzylic C-H amination catalysed by an engineered iron-haem enzyme.
Nat Chem, 9, 2017

 

123>

227111

건을2024-11-06부터공개중

PDB statisticsPDBj update infoContact PDBjnumon