5YYA
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![BU of 5yya by Molmil](/molmil-images/mine/5yya) | Crystal structure of Tandem Tudor Domain of human UHRF1 | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, SULFATE ION | 著者 | Kori, S, Defossez, P.A, Arita, K. | 登録日 | 2017-12-08 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation. Structure, 27, 2019
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2DW5
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![BU of 2dw5 by Molmil](/molmil-images/mine/2dw5) | Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide | 分子名称: | CALCIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, Protein-arginine deiminase type-4, ... | 著者 | Luo, Y, Arita, K, Sato, M, Thompson, P.R. | 登録日 | 2006-08-04 | 公開日 | 2006-10-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization Biochemistry, 45, 2006
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3WO3
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![BU of 3wo3 by Molmil](/molmil-images/mine/3wo3) | Crystal structure of IL-18 in complex with IL-18 receptor alpha | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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3WO4
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![BU of 3wo4 by Molmil](/molmil-images/mine/3wo4) | Crystal structure of the IL-18 signaling ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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3WO2
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![BU of 3wo2 by Molmil](/molmil-images/mine/3wo2) | Crystal structure of human interleukin-18 | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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2CT9
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![BU of 2ct9 by Molmil](/molmil-images/mine/2ct9) | The crystal structure of calcineurin B homologous proein 1 (CHP1) | 分子名称: | CALCIUM ION, Calcium-binding protein p22 | 著者 | Naoe, Y, Arita, K, Hashimoto, H, Kanazawa, H, Sato, M, Shimizu, T. | 登録日 | 2005-05-23 | 公開日 | 2005-07-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural characterization of calcineurin B homologous protein 1 J.Biol.Chem., 280, 2005
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3VXV
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![BU of 3vxv by Molmil](/molmil-images/mine/3vxv) | Crystal structure of methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*CP*(5CM)P*GP*GP*AP*CP*A)-3'), ... | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | 登録日 | 2012-09-21 | 公開日 | 2013-01-16 | 最終更新日 | 2013-08-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4 J.Biol.Chem., 288, 2013
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3VXX
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![BU of 3vxx by Molmil](/molmil-images/mine/3vxx) | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5CM)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | 登録日 | 2012-09-21 | 公開日 | 2013-01-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4 J.Biol.Chem., 288, 2013
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3VYQ
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![BU of 3vyq by Molmil](/molmil-images/mine/3vyq) | Crystal structure of the methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence in space group P1 | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*AP*TP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*AP*TP*GP*T)-3'), ... | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | 登録日 | 2012-10-02 | 公開日 | 2013-01-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.525 Å) | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4 J.Biol.Chem., 288, 2013
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3A4S
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![BU of 3a4s by Molmil](/molmil-images/mine/3a4s) | The crystal structure of the SLD2:Ubc9 complex | 分子名称: | NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 | 著者 | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | 登録日 | 2009-07-14 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009
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3A1B
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![BU of 3a1b by Molmil](/molmil-images/mine/3a1b) | Crystal structure of the DNMT3A ADD domain in complex with histone H3 | 分子名称: | 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ... | 著者 | Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M. | 登録日 | 2009-03-28 | 公開日 | 2009-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain Embo Rep., 10, 2009
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3B0F
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![BU of 3b0f by Molmil](/molmil-images/mine/3b0f) | Crystal structure of the UBA domain of p62 and its interaction with ubiquitin | 分子名称: | SULFATE ION, Sequestosome-1 | 著者 | Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H. | 登録日 | 2011-06-09 | 公開日 | 2011-06-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin. J.Biol.Chem., 286, 2011
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3A4R
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![BU of 3a4r by Molmil](/molmil-images/mine/3a4r) | The crystal structure of SUMO-like domain 2 in Nip45 | 分子名称: | 1,2-ETHANEDIOL, NFATC2-interacting protein, SULFATE ION | 著者 | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | 登録日 | 2009-07-14 | 公開日 | 2010-02-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009
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3VYB
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![BU of 3vyb by Molmil](/molmil-images/mine/3vyb) | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/hmCG sequence | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5HC)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | 登録日 | 2012-09-22 | 公開日 | 2013-01-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4 J.Biol.Chem., 288, 2013
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3W6H
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![BU of 3w6h by Molmil](/molmil-images/mine/3w6h) | Crystal structure of 19F probe-labeled hCAI in complex with acetazolamide | 分子名称: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 1, ... | 著者 | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | 登録日 | 2013-02-14 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.964 Å) | 主引用文献 | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR To be published
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3W6I
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![BU of 3w6i by Molmil](/molmil-images/mine/3w6i) | Crystal structure of 19F probe-labeled hCAI | 分子名称: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, Carbonic anhydrase 1, ZINC ION | 著者 | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | 登録日 | 2013-02-14 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | 主引用文献 | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR To be published
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3A1A
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![BU of 3a1a by Molmil](/molmil-images/mine/3a1a) | Crystal Structure of the DNMT3A ADD domain | 分子名称: | 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, ZINC ION | 著者 | Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M. | 登録日 | 2009-03-28 | 公開日 | 2009-11-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain Embo Rep., 10, 2009
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5YWX
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![BU of 5ywx by Molmil](/molmil-images/mine/5ywx) | Crystal structure of hematopoietic prostaglandin D synthase in complex with F092 | 分子名称: | GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ... | 著者 | Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Omura, A, Tanaka, A. | 登録日 | 2017-11-30 | 公開日 | 2018-09-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies. Bioorg. Med. Chem., 26, 2018
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5Y9Z
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![BU of 5y9z by Molmil](/molmil-images/mine/5y9z) | Crystal structure of rat hematopoietic prostaglandin D synthase | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLUTATHIONE, ... | 著者 | Kamo, M, Furubayashi, N, Inaka, K, Tanaka, H, Aritake, K, Urade, Y. | 登録日 | 2017-08-29 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Crystal structure of rat hematopoietic prostaglandin D synthase To Be Published
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5YX1
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![BU of 5yx1 by Molmil](/molmil-images/mine/5yx1) | Crystal structure of hematopoietic prostaglandin D synthase in complex with U004 | 分子名称: | GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ... | 著者 | Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Urade, Y, Takaya, D, Tanaka, A. | 登録日 | 2017-12-01 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Crystal structure of hematopoietic prostaglandin D synthase in complex with U004 To Be Published
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5YWE
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![BU of 5ywe by Molmil](/molmil-images/mine/5ywe) | Crystal structure of hematopoietic prostaglandin D synthase apo form | 分子名称: | GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ... | 著者 | Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Urade, Y. | 登録日 | 2017-11-29 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal structure of hematopoietic prostaglandin D synthase apo form To Be Published
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1V40
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![BU of 1v40 by Molmil](/molmil-images/mine/1v40) | First Inhibitor Complex Structure of Human Hematopoietic Prostaglandin D Synthase | 分子名称: | 3-(1,3-BENZOTHIAZOL-2-YL)-2-(1,4-DIOXO-1,2,3,4-TETRAHYDROPHTHALAZIN-6-YL)-5-[(E)-2-PHENYLVINYL]-3H-TETRAAZOL-2-IUM, GLUTATHIONE, GLYCEROL, ... | 著者 | Inoue, T, Okano, Y, Kado, Y, Aritake, K, Irikura, D, Uodome, N, Kinugasa, S, Okazaki, N, Matsumura, H, Kai, Y, Urade, Y. | 登録日 | 2003-11-07 | 公開日 | 2004-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase. J.Biochem.(Tokyo), 135, 2004
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2CZU
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![BU of 2czu by Molmil](/molmil-images/mine/2czu) | lipocalin-type prostaglandin D synthase | 分子名称: | Prostaglandin-H2 D-isomerase | 著者 | Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-17 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. J.Biol.Chem., 284, 2009
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2CZT
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![BU of 2czt by Molmil](/molmil-images/mine/2czt) | lipocalin-type prostaglandin D synthase | 分子名称: | Prostaglandin-H2 D-isomerase | 著者 | Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-17 | 公開日 | 2006-10-03 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. J.Biol.Chem., 284, 2009
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