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PDB: 15 results

6PQ5
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AGAAAA segment 113-118 from human prion
Descriptor: MALONATE ION, Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2019-07-08
Release date:2020-04-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
6PQA
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GAVVGG segment 119-124 from human prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2019-07-08
Release date:2020-04-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
4E1H
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BU of 4e1h by Molmil
Fragment of human prion protein
Descriptor: CITRIC ACID, FE (III) ION, Major prion protein
Authors:Apostol, M.I, Perry, K, Surewicz, W.K.
Deposit date:2012-03-06
Release date:2013-03-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013
4E1I
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Fragment of human prion protein
Descriptor: Major prion protein
Authors:Apostol, M.I, Surewicz, W.K.
Deposit date:2012-03-06
Release date:2013-03-06
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013
3NVF
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BU of 3nvf by Molmil
IIHFGS segment 138-143 from human prion
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVE
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BU of 3nve by Molmil
MMHFGN segment 138-143 from Syrian Hamster prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVG
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MIHFGN segment 137-142 from mouse prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NHC
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BU of 3nhc by Molmil
GYMLGS segment 127-132 from human prion with M129
Descriptor: Major prion protein
Authors:Apostol, M.I, Eisenberg, D.
Deposit date:2010-06-14
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
3NHD
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BU of 3nhd by Molmil
GYVLGS segment 127-132 from human prion with V129
Descriptor: ACETIC ACID, Major prion protein
Authors:Apostol, M.I, Eisenberg, D.
Deposit date:2010-06-14
Release date:2010-08-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
3NVH
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MIHFGND segment 137-143 from mouse prion
Descriptor: Major prion protein, trifluoroacetic acid
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3FVA
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BU of 3fva by Molmil
NNQNTF segment from elk prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Eisenberg, D.
Deposit date:2009-01-15
Release date:2009-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.458 Å)
Cite:Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
1NBU
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BU of 1nbu by Molmil
7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis
Descriptor: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, Probable dihydroneopterin aldolase
Authors:Goulding, C.W, Apostol, M.I, Sawaya, M.R, Phillips, M, Parseghian, A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-03
Release date:2004-01-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
1Z9W
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BU of 1z9w by Molmil
Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
Descriptor: Dihydroneopterin aldolase
Authors:Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-04-05
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
1LU4
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BU of 1lu4 by Molmil
1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS
Descriptor: SOLUBLE SECRETED ANTIGEN MPT53
Authors:Goulding, C.W, Apostol, M.I, Gleiter, S, Parseghian, A, Bardwell, J, Gennaro, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-21
Release date:2003-10-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Gram-positive DsbE Proteins Function Differently from Gram-negative DsbE Homologs: A STRUCTURE TO FUNCTION ANALYSIS OF DsbE FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 279, 2004
2ONX
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BU of 2onx by Molmil
NNQQ peptide corresponding to residues 8-11 of yeast prion sup35 (alternate crystal form)
Descriptor: peptide corresponding to residues 8-11 of yeast prion sup35
Authors:Sawaya, M.R, Sambashivan, S, Nelson, R, Ivanova, M, Sievers, S.A, Apostol, M.I, Thompson, M.J, Balbirnie, M, Wiltzius, J.J, McFarlane, H, Madsen, A.O, Riekel, C, Eisenberg, D.
Deposit date:2007-01-24
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007

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