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PDB: 17 件
6PQ5
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AGAAAA segment 113-118 from human prion
分子名称: MALONATE ION, Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
6PQA
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GAVVGG segment 119-124 from human prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
4E1H
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Fragment of human prion protein
分子名称: CITRIC ACID, FE (III) ION, Major prion protein
著者Apostol, M.I, Perry, K, Surewicz, W.K.
登録日2012-03-06
公開日2013-03-06
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013
4E1I
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Fragment of human prion protein
分子名称: Major prion protein
著者Apostol, M.I, Surewicz, W.K.
登録日2012-03-06
公開日2013-03-06
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013
3NVE
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MMHFGN segment 138-143 from Syrian Hamster prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVH
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MIHFGND segment 137-143 from mouse prion
分子名称: Major prion protein, trifluoroacetic acid
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVF
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IIHFGS segment 138-143 from human prion
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVG
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MIHFGN segment 137-142 from mouse prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NHC
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GYMLGS segment 127-132 from human prion with M129
分子名称: Major prion protein
著者Apostol, M.I, Eisenberg, D.
登録日2010-06-14
公開日2010-08-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
3NHD
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GYVLGS segment 127-132 from human prion with V129
分子名称: ACETIC ACID, Major prion protein
著者Apostol, M.I, Eisenberg, D.
登録日2010-06-14
公開日2010-08-04
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
2OL9
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Peptide corresponding to residues 170-175 of human prion
分子名称: peptide from human prion
著者Apostol, M.A, Sawaya, M.R, Eisenberg, D.
登録日2007-01-18
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
3FVA
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NNQNTF segment from elk prion
分子名称: Major prion protein
著者Apostol, M.I, Eisenberg, D.
登録日2009-01-15
公開日2009-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.458 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
1Z9W
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Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
分子名称: Dihydroneopterin aldolase
著者Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-04-05
公開日2005-04-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
1LMI
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1.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS-MPT63
分子名称: Immunogenic protein MPT63/MPB63
著者Goulding, C.W, Parseghian, A, Sawaya, M.R, Cascio, D, Apostol, M, Gennaro, M.L, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-05-01
公開日2002-12-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution
Protein Sci., 11, 2002
1NBU
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BU of 1nbu by Molmil
7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, Probable dihydroneopterin aldolase
著者Goulding, C.W, Apostol, M.I, Sawaya, M.R, Phillips, M, Parseghian, A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-12-03
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
1LU4
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BU of 1lu4 by Molmil
1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS
分子名称: SOLUBLE SECRETED ANTIGEN MPT53
著者Goulding, C.W, Apostol, M.I, Gleiter, S, Parseghian, A, Bardwell, J, Gennaro, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-05-21
公開日2003-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Gram-positive DsbE Proteins Function Differently from Gram-negative DsbE Homologs: A STRUCTURE TO FUNCTION ANALYSIS OF DsbE FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 279, 2004
2ONX
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NNQQ peptide corresponding to residues 8-11 of yeast prion sup35 (alternate crystal form)
分子名称: peptide corresponding to residues 8-11 of yeast prion sup35
著者Sawaya, M.R, Sambashivan, S, Nelson, R, Ivanova, M, Sievers, S.A, Apostol, M.I, Thompson, M.J, Balbirnie, M, Wiltzius, J.J, McFarlane, H, Madsen, A.O, Riekel, C, Eisenberg, D.
登録日2007-01-24
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007

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