8XBD
 
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2H05
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2HC7
 | | 2'-selenium-T A-DNA [G(TSe)GTACAC] | | Descriptor: | 5'-D(*GP*(2ST)P*GP*TP*AP*CP*AP*C)-3' | | Authors: | Jiang, J, Sheng, J, Huang, Z. | | Deposit date: | 2006-06-15 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structure of 2'-Selenium modified T A-DNA G(TSe)GTACAC
TO BE PUBLISHED
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3JBU
 | | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F. | | Deposit date: | 2015-10-16 | | Release date: | 2016-01-27 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
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4YUE
 | | Mouse IL-2 Bound to S4B6 Fab Fragment | | Descriptor: | GLYCEROL, Interleukin-2, S4B6 Fab heavy chain, ... | | Authors: | Spangler, J.B, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-03-18 | | Release date: | 2015-07-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.194 Å) | | Cite: | Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.
Immunity, 42, 2015
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6CXF
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2B3O
 | | Crystal structure of human tyrosine phosphatase SHP-1 | | Descriptor: | Tyrosine-protein phosphatase, non-receptor type 6 | | Authors: | Yang, J, Liu, L, He, D, Song, X, Liang, X, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2005-09-20 | | Release date: | 2005-10-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of human protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 278, 2003
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6BWF
 | | 4.1 angstrom Mg2+-unbound structure of mouse TRPM7 | | Descriptor: | TRPM7 | | Authors: | Zhang, J, Li, Z, Duan, J, Abiria, S.A, Clapham, D.E. | | Deposit date: | 2017-12-14 | | Release date: | 2018-08-15 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4YQX
 | | Mouse IL-2 Bound to JES6-1 scFv Fragment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-2, JES6-1 VH domain, ... | | Authors: | Spangler, J.B, Luca, V.C, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-03-13 | | Release date: | 2015-07-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.826 Å) | | Cite: | Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.
Immunity, 42, 2015
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6BWI
 | | 3.7 angstrom cryoEM structure of full length human TRPM4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | | Authors: | Zhang, J, Li, Z, Duan, J, Li, J, Clapham, D.E. | | Deposit date: | 2017-12-15 | | Release date: | 2018-12-19 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of full-length human TRPM4.
Proc.Natl.Acad.Sci.USA, 115, 2018
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5WER
 | | Crystal Structure of TAPBPR and H2-Dd complex | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ... | | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | | Deposit date: | 2017-07-10 | | Release date: | 2017-10-18 | | Last modified: | 2019-08-28 | | Method: | X-RAY DIFFRACTION (3.412 Å) | | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
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3BM0
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8XHO
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4EQE
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6CT0
 | | Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex | | Descriptor: | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | | Authors: | Jiang, J, Baiesc, F.L, Hiromasa, Y, Yu, X, Hui, W.H, Dai, X, Roche, T.E, Zhou, Z.H. | | Deposit date: | 2018-03-21 | | Release date: | 2018-04-18 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex.
Biochemistry, 57, 2018
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5WEU
 | | Crystal Structure of H2-Dd with disulfide-linked 10mer peptide | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Envelope glycoprotein gp160, ... | | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | | Deposit date: | 2017-07-10 | | Release date: | 2017-10-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.584 Å) | | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
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6CW6
 | | Structure of alpha-GC[8,18] bound by CD1d and in complex with the Va14Vb8.2 TCR | | Descriptor: | (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, J, Zajonc, D. | | Deposit date: | 2018-03-29 | | Release date: | 2019-04-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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6CXE
 | | Structure of alpha-GSA[26,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | Authors: | Wang, J, Zajonc, D. | | Deposit date: | 2018-04-02 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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5WET
 | | Crystal Structure of H2-Dd with disulfide-linked 6mer peptide | | Descriptor: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | | Deposit date: | 2017-07-10 | | Release date: | 2017-10-18 | | Last modified: | 2017-12-13 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
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6CXA
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7EXC
 | | Crystal structure of T2R-TTL-1129A2 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | Authors: | Yang, J.H, Yan, W. | | Deposit date: | 2021-05-26 | | Release date: | 2022-06-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure-Based Design and Synthesis of N-Substituted 3-Amino-beta-Carboline Derivatives as Potent alpha beta-Tubulin Degradation Agents
J.Med.Chem., 65, 2022
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4EQH
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6CWB
 | | Structure of alpha-GSA[8,4P] bound by CD1d and in complex with the Va14Vb8.2 TCR | | Descriptor: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-[(1E)-4-phenylbutylidene]-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, J, Zajonc, D. | | Deposit date: | 2018-03-30 | | Release date: | 2019-04-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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6CX9
 | | Structure of alpha-GSA[16,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | Authors: | Wang, J, Zajonc, D. | | Deposit date: | 2018-04-02 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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6CX5
 | | Structure of alpha-GSA[8,8P] bound by CD1d and in complex with the Va14Vb8.2 TCR | | Descriptor: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(8-phenyloctyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, J, Zajonc, D. | | Deposit date: | 2018-04-02 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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