6DGL
 
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8QRT
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8QS0
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6DGR
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4RP9
 | | Bacterial vitamin C transporter UlaA/SgaT in C2 form | | Descriptor: | ASCORBIC ACID, Ascorbate-specific permease IIC component UlaA, PENTAETHYLENE GLYCOL, ... | | Authors: | Wang, J.W. | | Deposit date: | 2014-10-29 | | Release date: | 2015-03-04 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.651 Å) | | Cite: | Crystal structure of a phosphorylation-coupled vitamin C transporter.
Nat.Struct.Mol.Biol., 22, 2015
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6DGP
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5UY8
 | | Crystal structure of AICARFT bound to an antifolate | | Descriptor: | 5-[(5S)-5-ethyl-5-methyl-6-oxo-1,4,5,6-tetrahydropyridin-3-yl]-N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)thiophene-2-sulfonamide, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, ... | | Authors: | Wang, J, Wang, Y, Fales, K.R, Atwell, S, Clawson, D. | | Deposit date: | 2017-02-23 | | Release date: | 2018-01-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.
J. Med. Chem., 60, 2017
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5XLN
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3SR9
 | | Crystal structure of mouse PTPsigma | | Descriptor: | Receptor-type tyrosine-protein phosphatase S | | Authors: | Wang, J, Hou, L, Li, J, Ding, J. | | Deposit date: | 2011-07-07 | | Release date: | 2012-05-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural insights into the homology and differences between mouse protein tyrosine phosphatase-sigma and human protein tyrosine phosphatase-sigma
Acta Biochim.Biophys.Sin., 43, 2011
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6C6U
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound with NusG | | Descriptor: | DNA (29-MER), DNA-DIRECTED RNA POLYMERASE BETA', DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A. | | Deposit date: | 2018-01-19 | | Release date: | 2018-07-25 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Cell, 173, 2018
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3J9C
 | | CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution | | Descriptor: | CALCIUM ION, Protective antigen PA-63 | | Authors: | Jiang, J, Pentelute, B.L, Collier, R.J, Zhou, Z.H. | | Deposit date: | 2014-12-25 | | Release date: | 2015-03-11 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Atomic structure of anthrax protective antigen pore elucidates toxin translocation.
Nature, 521, 2015
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5ZCJ
 | | Crystal structure of complex | | Descriptor: | TP53-binding protein 1, Tudor-interacting repair regulator protein | | Authors: | Wang, J, Yuan, Z, Cui, Y, Xie, R, Wang, M, Ma, Y, Yu, X, Liu, X. | | Deposit date: | 2018-02-17 | | Release date: | 2018-06-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.004 Å) | | Cite: | Crystal structure of complex
To Be Published
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3PLS
 | | RON in complex with ligand AMP-PNP | | Descriptor: | MAGNESIUM ION, Macrophage-stimulating protein receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Wang, J, Steinbacher, S, Augustin, M, Schreiner, P, Epstein, D, Mulvihill, M.J, Crew, A.P. | | Deposit date: | 2010-11-15 | | Release date: | 2010-11-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | The Crystal Structure of a Constitutively Active Mutant RON Kinase Suggests an Intramolecular Autophosphorylation Hypothesis
Biochemistry, 49, 2010
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4DOM
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5Z8U
 | | Human mitochondrial ferritin mutant - C102A/C130A | | Descriptor: | Ferritin, mitochondrial, MAGNESIUM ION | | Authors: | Zang, J, Zheng, B, Zhao, G. | | Deposit date: | 2018-02-01 | | Release date: | 2019-02-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17, 2019
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3CXQ
 | | Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 bound to GlcN6P | | Descriptor: | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, Glucosamine 6-phosphate N-acetyltransferase | | Authors: | Wang, J, Liu, X, Li, L.-F, Su, X.-D. | | Deposit date: | 2008-04-25 | | Release date: | 2008-09-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
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5BV2
 | | Crystal structure of E. coli HPII catalase variant | | Descriptor: | 1,2-ETHANEDIOL, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase HPII, ... | | Authors: | Wang, J, Lomkalin, I.V. | | Deposit date: | 2015-06-04 | | Release date: | 2015-06-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Influence of weak-intensity data, ordered water molecules, and hydrogen atoms on the refinement of a large protein crystal structure
To be Published
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4LR3
 | | Crystal structure of E. coli YfbU at 2.5 A resolution | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, protein YfbU | | Authors: | Wang, J, Wing, R.A. | | Deposit date: | 2013-07-19 | | Release date: | 2014-04-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Diamonds in the rough: a strong case for the inclusion of weak-intensity X-ray diffraction data.
Acta Crystallogr.,Sect.D, 70, 2014
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4CCP
 | | X-RAY STRUCTURES OF RECOMBINANT YEAST CYTOCHROME C PEROXIDASE AND THREE HEME-CLEFT MUTANTS PREPARED BY SITE-DIRECTED MUTAGENESIS | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, YEAST CYTOCHROME C PEROXIDASE | | Authors: | Wang, J, Mauro, J.M, Edwards, S.L, Oatley, S.J, Fishel, L.A, Ashford, V.A, Xuong, N.-H, Kraut, J. | | Deposit date: | 1990-02-28 | | Release date: | 1991-07-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | X-ray structures of recombinant yeast cytochrome c peroxidase and three heme-cleft mutants prepared by site-directed mutagenesis.
Biochemistry, 29, 1990
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3GIO
 | | Crystal structure of the TNF-alpha inducing protein (Tip alpha) from Helicobacter pylori | | Descriptor: | Putative uncharacterized protein | | Authors: | Jang, J.Y, Yoon, H.J, Yoon, J.Y, Kim, H.S, Lee, S.J, Kim, K.H, Kim, D.J, Han, B.G, Lee, B.I, Jang, S, Suh, S.W. | | Deposit date: | 2009-03-05 | | Release date: | 2009-08-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of the TNF-alpha-Inducing Protein (Tipalpha) from Helicobacter pylori: Insights into Its DNA-Binding Activity.
J.Mol.Biol., 2009
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7F0Y
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7F13
 | | Crystal structure of isomerase Dcr3 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Dcr3 | | Authors: | Yang, J, Mori, T, Abe, I. | | Deposit date: | 2021-06-07 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7F11
 | | Crystal structure of NsrQ M128I in complex with substrate analogue 7 | | Descriptor: | NsrQ, methyl 2-[2,6-bis(oxidanyl)phenyl]carbonyl-5-methyl-3,6-bis(oxidanyl)benzoate | | Authors: | Yang, J, Mori, T, Abe, I. | | Deposit date: | 2021-06-07 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7F14
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7F0Z
 | | Crystal structure of NsrQ W31A | | Descriptor: | NsrQ | | Authors: | Yang, J, Mori, T, Abe, I. | | Deposit date: | 2021-06-07 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification.
Angew.Chem.Int.Ed.Engl., 60, 2021
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