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PDB: 46 件

1AL1
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CRYSTAL STRUCTURE OF ALPHA1: IMPLICATIONS FOR PROTEIN DESIGN
分子名称: ALPHA HELIX PEPTIDE: ELLKKLLEELKG, SULFATE ION
著者Hill, C.P, Anderson, D.H, Wesson, L, Degrado, W.F, Eisenberg, D.
登録日1990-07-02
公開日1991-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of alpha 1: implications for protein design.
Science, 249, 1990
1NOH
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The structure of bacteriophage phi29 scaffolding protein gp7 after prohead assembly
分子名称: HEAD MORPHOGENESIS PROTEIN
著者Morais, M.C, Kanamaru, S, Badasso, M.O, Koti, J.S, Owen, B.L, McMurray, C.T, L Anderson, D, Rossmann, M.G.
登録日2003-01-16
公開日2003-07-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bacteriophage f29 scaffolding protein gp7 before and after prohead assembly
Nat.Struct.Biol., 10, 2003
1FOQ
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PENTAMERIC MODEL OF THE BACTERIOPHAGE PHI29 PROHEAD RNA
分子名称: BACTERIOPHAGE PHI29 PROHEAD RNA
著者Simpson, A.A, Tao, Y, Leiman, P.G, Badasso, M.O, He, Y, Jardine, P.J, Olson, N.H, Morais, M.C, Grimes, S, Anderson, D.L, Baker, T.S, Rossmann, M.G.
登録日2000-08-28
公開日2000-12-22
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Structure of the bacteriophage phi29 DNA packaging motor.
Nature, 408, 2000
1NO4
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Crystal Structure of the pre-assembly scaffolding protein gp7 from the double-stranded DNA bacteriophage phi29
分子名称: HEAD MORPHOGENESIS PROTEIN
著者Morais, M.C, Kanamaru, S, Badasso, M.O, Koti, J.S, Owen, B.A.L, McMurray, C.T, Anderson, D.L, Rossmann, M.G.
登録日2003-01-15
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bacteriophage f29 scaffolding protein gp7 before and after prohead assembly
Nat.Struct.Biol., 10, 2003
1XAE
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Crystal structure of wild type yellow fluorescent protein zFP538 from Zoanthus
分子名称: BETA-MERCAPTOETHANOL, fluorescent protein FP538
著者Remington, S.J, Wachter, R.M, Yarbrough, D.K, Branchaud, B, Anderson, D.C, Kallio, K, Lukyanov, K.A.
登録日2004-08-25
公開日2005-02-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献zFP538, a yellow-fluorescent protein from Zoanthus, contains a novel three-ring chromophore.
Biochemistry, 44, 2005
1XA9
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Crystal structure of yellow fluorescent protein zFP538 K66M green mutant
分子名称: BETA-MERCAPTOETHANOL, fluorescent protein FP538
著者Remington, S.J, Wachter, R.M, Yarbrough, D.K, Branchaud, B, Anderson, D.C, Kallio, K, Lukyanov, K.A.
登録日2004-08-25
公開日2005-02-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献zFP538, a yellow-fluorescent protein from Zoanthus, contains a novel three-ring chromophore.
Biochemistry, 44, 2005
1G9U
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CRYSTAL STRUCTURE OF YOPM-LEUCINE RICH EFFECTOR PROTEIN FROM YERSINIA PESTIS
分子名称: ACETATE ION, CALCIUM ION, MERCURY (II) ION, ...
著者Evdokimov, A.G, Anderson, D.E, Routzahn, K.M, Waugh, D.S.
登録日2000-11-28
公開日2001-10-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit.
J.Mol.Biol., 312, 2001
1FOU
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CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29
分子名称: UPPER COLLAR PROTEIN
著者Simpson, A.A, Tao, Y, Leiman, P.G, Badasso, M.O, He, Y, Jardine, P.J, Olson, N.H, Morais, M.C, Grimes, S.N, Anderson, D.L, Baker, T.S, Rossmann, M.G.
登録日2000-08-28
公開日2000-12-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the bacteriophage phi29 DNA packaging motor.
Nature, 408, 2000
1YXN
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Pseudo-atomic model of a fiberless isometric variant of bacteriophage phi29
分子名称: Major head protein
著者Morais, M.C, Choi, K.H, Koti, J.S, Chipman, P.R, Anderson, D.L, Rossmann, M.G.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Conservation of the Capsid Structure in Tailed dsDNA Bacteriophages: the Pseudoatomic Structure of phi29
Mol.Cell, 18, 2005
4GID
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Structure of beta-secretase complexed with inhibitor
分子名称: Beta-secretase 1, L-PROLINAMIDE, N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
著者Ghosh, A, Tang, J, Venkateswara, R.K, Yadav, N, Anderson, D, Gavande, N, Huang, X, Terzyan, S.
登録日2012-08-08
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure.
J.Med.Chem., 55, 2012
4DST
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: 1,2-ETHANEDIOL, 2-(4,6-dichloro-2-methyl-1H-indol-3-yl)ethanamine, ACETATE ION, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSN
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: 1,2-ETHANEDIOL, GTPase KRas, isoform 2B, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSO
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSU
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: BENZIMIDAZOLE, GTPase KRas, isoform 2B, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
1JNB
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CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29
分子名称: UPPER COLLAR PROTEIN
著者Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M.O, Jardine, P.J, Anderson, D.L, Rossmann, M.G.
登録日2001-07-23
公開日2001-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure determination of the head-tail connector of bacteriophage phi29.
Acta Crystallogr.,Sect.D, 57, 2001
1HYK
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AGOUTI-RELATED PROTEIN (87-132) (AC-AGRP(87-132))
分子名称: AGOUTI RELATED PROTEIN
著者Bolin, K.A, Anderson, D.J, Trulson, J.A, Thompson, D.A, Wilken, J, Kent, S.B.H, Millhauser, G.L.
登録日2001-01-19
公開日2001-02-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR structure of a minimized human agouti related protein prepared by total chemical synthesis.
FEBS Lett., 451, 1999
1JL5
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Novel Molecular Architecture of YopM-a Leucine-rich Effector Protein from Yersinia pestis
分子名称: CALCIUM ION, outer protein YopM
著者Evdokimov, A.G, Anderson, D.E, Routzahn, K.M, Waugh, D.S.
登録日2001-07-15
公開日2001-10-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit.
J.Mol.Biol., 312, 2001
4HCT
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Crystal structure of ITK in complex with compound 52
分子名称: 3-{1-[(3R)-1-acryloylpiperidin-3-yl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-N-(3-tert-butylphenyl)benzamide, Tyrosine-protein kinase ITK/TSK
著者Zapf, C.W, Gerstenberger, B.S, Xing, L, Limburg, D.C, Anderson, D.R, Caspers, N, Han, S, Aulabaugh, A, Kurumbail, R, Shakya, S, Li, X, Spaulding, V, Czerwinski, R.M, Seth, N, Medley, Q.G.
登録日2012-10-01
公開日2012-11-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Covalent inhibitors of interleukin-2 inducible T cell kinase (itk) with nanomolar potency in a whole-blood assay.
J.Med.Chem., 55, 2012
1IJG
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Structure of the Bacteriophage phi29 Head-Tail Connector Protein
分子名称: UPPER COLLAR PROTEIN
著者Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M, Jardine, P.J, Anderson, D.L, Rossmann, M.G.
登録日2001-04-26
公開日2001-05-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure determination of the head-tail connector of bacteriophage phi29.
Acta Crystallogr.,Sect.D, 57, 2001
3OMV
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Crystal structure of c-raf (raf-1)
分子名称: (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime, RAF proto-oncogene serine/threonine-protein kinase
著者Hatzivassiliou, G, Song, K, Yen, I, Brandhuber, B.J, Anderson, D.J, Alvarado, R, Ludlam, M.J, Stokoe, D, Gloor, S.L, Vigers, G.P.A, Morales, T, Aliagas, I, Liu, B, Sideris, S, Hoeflich, K.P, Jaiswal, B.S, Seshagiri, S, Koeppen, H, Belvin, M, Friedman, L.S, Malek, S.
登録日2010-08-27
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Nature, 464, 2010
3R4F
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Prohead RNA
分子名称: MAGNESIUM ION, pRNA
著者Ding, F, Lu, C, Zhano, W, Rajashankar, K.R, Anderson, D.L, Jardine, P.J, Grimes, S, Ke, A.
登録日2011-03-17
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure and assembly of the essential RNA ring component of a viral DNA packaging motor.
Proc.Natl.Acad.Sci.USA, 108, 2011
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