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PDB: 114 件
9EQ3
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BU of 9eq3 by Molmil
Structure of IgE HMM5 bound to FceRIa cryo-EM class 8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
著者Andersen, G.R, Jensen, R.K.
登録日2024-03-20
公開日2024-04-10
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献The dynamics of hinge flexibility in receptor bound immunoglobulin E revealed by electron microscopy
Biorxiv, 2023
9EQ4
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BU of 9eq4 by Molmil
Structure of IgE HMM5 bound to FceRIa cryo-EM class 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
著者Andersen, G.R, Jensen, R.K.
登録日2024-03-20
公開日2024-04-03
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献The dynamics of hinge flexibility in receptor bound immunoglobulin E revealed by electron microscopy
Biorxiv, 2023
8Q78
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Structure of the FP specific VHH TPP-3077
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, TPP-3077 VHH
著者Andersen, G.R, Pedersen, D.V.
登録日2023-08-15
公開日2024-08-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.225 Å)
主引用文献Structure of the FP specific VHH TPP-3077
To Be Published
8Q6R
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BU of 8q6r by Molmil
Structure of complement FP in complex with the TPP-3077 VHH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOCHOLIC ACID, ...
著者Andersen, G.R, Pedersen, D.V.
登録日2023-08-14
公開日2024-08-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of complement FP in complex with the TPP-3077 VHH
To Be Published
8R61
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BU of 8r61 by Molmil
Structure of IgE delta epsilon 3-4 in complex with a kappa binding nanobody
分子名称: HMM5 IgE light chain, Immunoglobulin E VH-Ceps1-Ceps1, kappa binding nanobody
著者Andersen, G.R, Gandini, R.
登録日2023-11-20
公開日2023-11-29
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The dynamics of hinge flexibility in receptor bound immunoglobulin E revealed by electron microscopy
Biorxiv, 2023
3EX7
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BU of 3ex7 by Molmil
The crystal structure of EJC in its transition state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Eukaryotic initiation factor 4A-III, ...
著者Andersen, G.R, Nielsen, K.H.
登録日2008-10-16
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
6XZU
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BU of 6xzu by Molmil
Complex of C-terminal domain of murine complement C3b with the hC3Nb3 nanobody
分子名称: Complement C3, nanobody hC3Nb1
著者Andersen, G.R, Pedersen, H.
登録日2020-02-05
公開日2020-08-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
J Immunol., 205, 2020
8COE
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BU of 8coe by Molmil
complement C5 in complex with the LCP0195 nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ...
著者Andersen, G.R, Pedersen, D.V.
登録日2023-02-28
公開日2024-01-03
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.
Mol.Immunol., 165, 2023
5I8O
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BU of 5i8o by Molmil
HMM5 Fab in complex with disaccharide
分子名称: HMM5 antibody heavy chain, HMM5 antibody light chain, alpha-L-fucopyranose-(1-3)-methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside
著者Andersen, G.R, Tjerrild, L.M, Spillner, E.
登録日2016-02-19
公開日2016-03-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of HMM5 Fab with a bound disaccharide
To be published
8CEM
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BU of 8cem by Molmil
Structure of bovine native C3, re-refinement
分子名称: Complement C3 alpha chain, Complement C3 beta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Andersen, G.R, Fredslund, F.
登録日2023-02-02
公開日2023-04-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of bovine complement component 3 reveals the basis for thioester function.
J Mol Biol, 361, 2006
8C1C
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BU of 8c1c by Molmil
Structure of IgE bound to the ectodomain of FceRIa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
著者Andersen, G.R, Jensen, R.K.
登録日2022-12-20
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of IgE bound to the ectodomain of FceRIa
To Be Published
8C1B
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BU of 8c1b by Molmil
Focused map for structure of IgE bound to the ectodomain of FceRIa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, Immunoglobulin heavy constant epsilon, ...
著者Andersen, G.R, Jensen, R.K.
登録日2022-12-20
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of IgE bound to the ectodomain of FceRIa
To Be Published
5I8K
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BU of 5i8k by Molmil
HHH1 Fab fragment
分子名称: HHH1 Fab Heavy chain, HHH1 Fab Light chain
著者Andersen, G.R, Spillner, E.
登録日2016-02-19
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.771 Å)
主引用文献HHH1 Fab fragment
To be published
7ASC
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BU of 7asc by Molmil
TGFBIp mutant A546T
分子名称: Transforming growth factor-beta-induced protein ig-h3
著者Andersen, G.R, Nielsen, N.S, Gadeberg, T.A.F.
登録日2020-10-27
公開日2020-12-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (4.8 Å)
主引用文献Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
7AS7
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BU of 7as7 by Molmil
Crystal structure of the GCD-associated TGFBIp mutant R124H
分子名称: Transforming growth factor-beta-induced protein ig-h3
著者Andersen, G.R, Gadeberg, T.A.F, Nielsen, N.S, Enghild, J.J.
登録日2020-10-27
公開日2020-12-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
1IJE
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BU of 1ije by Molmil
Nucleotide Exchange Intermediates in the eEF1A-eEF1Ba Complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, elongation factor 1-alpha, elongation factor 1-beta
著者Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
登録日2001-04-26
公開日2001-05-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJF
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BU of 1ijf by Molmil
Nucleotide exchange mechanisms in the eEF1A-eEF1Ba complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, elongation factor 1-alpha, ...
著者Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
登録日2001-04-26
公開日2001-05-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
7Q1Y
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BU of 7q1y by Molmil
X-ray structure of human A2ML1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin-like protein 1, ...
著者Andersen, G.R, Zarantonello, A, Enghild, J.J, Nielsen, N.S.
登録日2021-10-22
公開日2022-04-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
1G7C
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BU of 1g7c by Molmil
YEAST EEF1A:EEF1BA IN COMPLEX WITH GDPNP
分子名称: ELONGATION FACTOR 1-ALPHA, ELONGATION FACTOR 1-BETA, GUANOSINE-5'-MONOPHOSPHATE
著者Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
登録日2000-11-10
公開日2000-12-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1D2E
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BU of 1d2e by Molmil
CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
分子名称: ELONGATION FACTOR TU (EF-TU), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Andersen, G.R, Thirup, S, Spremulli, L.L, Nyborg, J.
登録日1999-09-23
公開日1999-09-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1F60
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BU of 1f60 by Molmil
CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
分子名称: ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
著者Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J.
登録日2000-06-19
公開日2000-07-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
6EHG
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BU of 6ehg by Molmil
complement component C3b in complex with a nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jensen, R.K, Andersen, K.R, Gadeberg, T.A.F, Laursen, N.S, Andersen, G.R.
登録日2017-09-13
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J. Biol. Chem., 293, 2018
4F4O
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BU of 4f4o by Molmil
Structure of the Haptoglobin-Haemoglobin Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, ...
著者Andersen, C.B.F, Torvund-Jensen, M, Nielsen, M.J, Oliveira, C.L.P, Hersleth, H.P, Andersen, N.H, Pedersen, J.S, Andersen, G.R, Moestrup, S.K.
登録日2012-05-11
公開日2012-08-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the haptoglobin-haemoglobin complex.
Nature, 489, 2012
3PRX
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BU of 3prx by Molmil
Structure of Complement C5 in Complex with CVF and SSL7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ...
著者Laursen, N.S, Andersen, G.R, Sottrup-Jensen, L, Andersen, K.R, Spillner, E, Braren, I.
登録日2010-11-30
公開日2011-01-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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BU of 3pvm by Molmil
Structure of Complement C5 in Complex with CVF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5
著者Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R.
登録日2010-12-07
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011

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