1B7B
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![BU of 1b7b by Molmil](/molmil-images/mine/1b7b) | Carbamate kinase from Enterococcus faecalis | Descriptor: | CARBAMATE KINASE, SULFATE ION | Authors: | Marina, A, Alzari, P.M, Bravo, J, Uriarte, M, Barcelona, B, Fita, I, Rubio, V. | Deposit date: | 1999-01-20 | Release date: | 2000-01-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine. Protein Sci., 8, 1999
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2F19
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![BU of 2f19 by Molmil](/molmil-images/mine/2f19) | THREE-DIMENSIONAL STRUCTURE OF TWO CRYSTAL FORMS OF FAB R19.9, FROM A MONOCLONAL ANTI-ARSONATE ANTIBODY | Descriptor: | IGG2B-KAPPA R19.9 FAB (HEAVY CHAIN), IGG2B-KAPPA R19.9 FAB (LIGHT CHAIN) | Authors: | Lascombe, M.B, Alzari, P.M, Poljak, R.J, Nisonoff, A. | Deposit date: | 1992-05-27 | Release date: | 1992-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody. Proc.Natl.Acad.Sci.USA, 89, 1992
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1HHP
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1MZ5
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![BU of 1mz5 by Molmil](/molmil-images/mine/1mz5) | Trypanosoma rangeli sialidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, sialidase | Authors: | Buschiazzo, A, Tavares, G.A, Campetella, O, Spinelli, S, Cremona, M.L, Paris, G, Amaya, M.F, Frasch, A.C.C, Alzari, P.M. | Deposit date: | 2002-10-05 | Release date: | 2002-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of sialyltransferase activity in trypanosomal sialidases Embo J., 19, 2000
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1MS1
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![BU of 1ms1 by Molmil](/molmil-images/mine/1ms1) | Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA) | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MR5
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![BU of 1mr5 by Molmil](/molmil-images/mine/1mr5) | Orthorhombic form of Trypanosoma cruzi trans-sialidase | Descriptor: | trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-18 | Release date: | 2003-03-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MS8
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![BU of 1ms8 by Molmil](/molmil-images/mine/1ms8) | Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA) | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MS5
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![BU of 1ms5 by Molmil](/molmil-images/mine/1ms5) | Triclinic form of Trypanosoma cruzi trans-sialidase, soaked with N-acetylneuraminyl-a-2,3-thio-galactoside (NA-S-Gal) | Descriptor: | trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MZ6
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![BU of 1mz6 by Molmil](/molmil-images/mine/1mz6) | Trypanosoma rangeli sialidase in complex with the inhibitor DANA | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, sialidase | Authors: | Buschiazzo, A, Tavares, G.A, Campetella, O, Spinelli, S, Cremona, M.L, Paris, G, Amaya, M.F, Frasch, A.C.C, Alzari, P.M. | Deposit date: | 2002-10-05 | Release date: | 2002-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of sialyltransferase activity in trypanosomal sialidases Embo J., 19, 2000
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1MS0
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![BU of 1ms0 by Molmil](/molmil-images/mine/1ms0) | Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)and lactose | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MS3
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![BU of 1ms3 by Molmil](/molmil-images/mine/1ms3) | Monoclinic form of Trypanosoma cruzi trans-sialidase | Descriptor: | trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MS4
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![BU of 1ms4 by Molmil](/molmil-images/mine/1ms4) | Triclinic form of Trypanosoma cruzi trans-sialidase | Descriptor: | trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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1MS9
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![BU of 1ms9 by Molmil](/molmil-images/mine/1ms9) | Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with lactose | Descriptor: | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | Deposit date: | 2002-09-19 | Release date: | 2003-03-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme of Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
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2BMX
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![BU of 2bmx by Molmil](/molmil-images/mine/2bmx) | Mycobacterium tuberculosis AhpC | Descriptor: | ALKYL HYDROPEROXIDASE C | Authors: | Guimaraes, B.G, Alzari, P.M. | Deposit date: | 2005-03-16 | Release date: | 2005-05-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Mechanism of the Alkyl Hydroperoxidase Ahpc, a Key Element of the Mycobacterium Tuberculosis Defense System Against Oxidative Stress. J.Biol.Chem., 280, 2005
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2CM1
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![BU of 2cm1 by Molmil](/molmil-images/mine/2cm1) | Crystal structure of the catalytic domain of serine threonine protein phosphatase PstP in complex with 2 Manganese ions. | Descriptor: | GLYCEROL, MANGANESE (II) ION, SERINE THREONINE PROTEIN PHOSPHATASE PSTP | Authors: | Wehenkel, A, Villarino, A, Bellinzoni, M, Alzari, P.M. | Deposit date: | 2006-05-03 | Release date: | 2007-06-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Binding Studies of the Three-Metal Center in Two Mycobacterial Ppm Ser/Thr Protein Phosphatases. J.Mol.Biol., 374, 2007
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2CE3
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![BU of 2ce3 by Molmil](/molmil-images/mine/2ce3) | CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS | Descriptor: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | Authors: | Segelke, B, Kim, C.Y, Ortiz-Lombardia, M, Alzari, P.M, Lekin, T. | Deposit date: | 2006-02-03 | Release date: | 2006-02-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1. Acta Crystallogr.,Sect.D, 63, 2007
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2CBY
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![BU of 2cby by Molmil](/molmil-images/mine/2cby) | Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis | Descriptor: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | Authors: | Mate, M.J, Portnoi, D, Alzari, P.M, Ortiz-Lombardia, M. | Deposit date: | 2006-01-10 | Release date: | 2006-01-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1. Acta Crystallogr.,Sect.D, 63, 2007
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2CDN
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![BU of 2cdn by Molmil](/molmil-images/mine/2cdn) | Crystal structure of Mycobacterium tuberculosis adenylate kinase complexed with two molecules of ADP and Mg | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINASE, MAGNESIUM ION | Authors: | Bellinzoni, M, Haouz, A, Grana, M, Munier-Lehmann, H, Alzari, P.M. | Deposit date: | 2006-01-25 | Release date: | 2006-05-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Crystal Structure of Mycobacterium Tuberculosis Adenylate Kinase in Complex with Two Molecules of Adp and Mg2+ Supports an Associative Mechanism for Phosphoryl Transfer. Protein Sci., 15, 2006
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2CKD
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![BU of 2ckd by Molmil](/molmil-images/mine/2ckd) | Crystal structure of ML2640 from Mycobacterium leprae | Descriptor: | PUTATIVE S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE ML2640 | Authors: | Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Alzari, P.M. | Deposit date: | 2006-04-17 | Release date: | 2007-05-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria. Protein Sci., 16, 2007
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2F3X
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2FHR
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![BU of 2fhr by Molmil](/molmil-images/mine/2fhr) | Trypanosoma Rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate) | Descriptor: | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, GLYCEROL, SULFATE ION, ... | Authors: | Amaya, M.F, Alzari, P.M, Buschiazzo, A. | Deposit date: | 2005-12-26 | Release date: | 2006-01-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase. J.Biol.Chem., 281, 2006
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2F41
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2FWV
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![BU of 2fwv by Molmil](/molmil-images/mine/2fwv) | Crystal Structure of Rv0813 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, hypothetical protein MtubF_01000852 | Authors: | Shepard, W, Haouz, A, Grana, M, Buschiazzo, A, Betton, J.M, Cole, S.T, Alzari, P.M, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-02-03 | Release date: | 2006-08-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of Rv0813c from Mycobacterium tuberculosis Reveals a New Family of Fatty Acid-Binding Protein-Like Proteins in Bacteria J.Bacteriol., 189, 2007
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2FUM
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![BU of 2fum by Molmil](/molmil-images/mine/2fum) | Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone | Descriptor: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Probable serine/threonine-protein kinase pknB | Authors: | Wehenkel, A, Alzari, P.M. | Deposit date: | 2006-01-27 | Release date: | 2006-08-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria Febs Lett., 580, 2006
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1JHL
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![BU of 1jhl by Molmil](/molmil-images/mine/1jhl) | THREE-DIMENSIONAL STRUCTURE OF A HETEROCLITIC ANTIGEN-ANTIBODY CROSS-REACTION COMPLEX | Descriptor: | IGG1-KAPPA D11.15 FV (HEAVY CHAIN), IGG1-KAPPA D11.15 FV (LIGHT CHAIN), PHEASANT EGG WHITE LYSOZYME | Authors: | Chitarra, V, Alzari, P.M, Bentley, G.A, Bhat, T.N, Eisele, J.-L, Poljak, R.J. | Deposit date: | 1993-05-04 | Release date: | 1994-01-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex. Proc.Natl.Acad.Sci.USA, 90, 1993
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