1MS9

Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with lactose

Summary for 1MS9

Entry DOI	10.2210/pdb1ms9/pdb
Related	1MR5 1MS0 1MS1 1MS3 1MS4 1MS5 1MS8 1MZ5 1MZ6
Related PRD ID	PRD_900004
Descriptor	trans-sialidase, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sialidase, trans-glycosylation, protein-acrbohydrate interactions, beta-propeller, hydrolase
Biological source	Trypanosoma cruzi
Total number of polymer chains	2
Total formula weight	143463.11
Authors	Buschiazzo, A.,Amaya, M.F.,Cremona, M.L.,Frasch, A.C.,Alzari, P.M. (deposition date: 2002-09-19, release date: 2003-03-25, Last modification date: 2021-10-27)
Primary citation	Buschiazzo, A.,Amaya, M.F.,Cremona, M.L.,Frasch, A.C.,Alzari, P.M. The crystal structure and mode of action of trans-sialidase, a key enzyme of Trypanosoma cruzi pathogenesis Mol.Cell, 10:757-768, 2002 Cited by PubMed: 12419220 DOI: 10.1016/S1097-2765(02)00680-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation