1MR5

Orthorhombic form of Trypanosoma cruzi trans-sialidase

Summary for 1MR5

• Entry DOI: 10.2210/pdb1mr5/pdb
• Related: 1MS0 1MS1 1MS3 1MS4 1MS5 1MS8 1MS9 1MZ5 1MZ6
• Descriptor: trans-sialidase (2 entities in total)
• Functional Keywords: transglycosylation, beta-propeller, protein-carbohydrate interactions, sialidase, hydrolase
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 1
• Total formula weight: 71389.26

Authors

Buschiazzo, A.,Amaya, M.F.,Cremona, M.L.,Frasch, A.C.,Alzari, P.M. (deposition date: 2002-09-18, release date: 2003-03-18, Last modification date: 2021-10-27)

• Primary citation: Buschiazzo, A.,Amaya, M.F.,Cremona, M.L.,Frasch, A.C.,Alzari, P.M.; The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis; Mol.Cell, 10:757-768, 2002; PubMed: 12419220; DOI: 10.1016/S1097-2765(02)00680-9

Experimental method

X-RAY DIFFRACTION (2.25 Å)