1Q5W
| Ubiquitin Recognition by Npl4 Zinc-Fingers | 分子名称: | Ubiquitin, ZINC ION, homolog of yeast nuclear protein localization 4 | 著者 | Alam, S.L, Sun, J, Payne, M, Welch, B.D, Blake, B.K, Davis, D.R, Meyer, H.H, Emr, S.D, Sundquist, W.I. | 登録日 | 2003-08-11 | 公開日 | 2004-03-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Ubiquitin interactions of NZF zinc fingers. Embo J., 23, 2004
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1U7H
| Structure and a Proposed Mechanism for Ornithine Cyclodeaminase from Pseudomonas putida | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | 著者 | Alam, S, Goodman, J.L, Wang, S, Ruzicka, F.J, Frey, P.A, Wedekind, J.E. | 登録日 | 2004-08-03 | 公開日 | 2004-11-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Ornithine Cyclodeaminase: Structure, Mechanism of Action, and Implications for
the u-Crystallin Family; Biochemistry, 43, 2004
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2HTH
| Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | 分子名称: | Ubiquitin, Vacuolar protein sorting protein 36 | 著者 | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | 登録日 | 2006-07-25 | 公開日 | 2006-10-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
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2D2L
| Crystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U39 | 分子名称: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | 登録日 | 2005-09-11 | 公開日 | 2005-11-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn Biochemistry, 44, 2005
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7LP5
| Structure of Nedd4L WW3 domain | 分子名称: | Angiomotin,E3 ubiquitin-protein ligase NEDD4-like | 著者 | Alam, S.L, Alian, A, Thompson, T, Rheinemann, L, Volkman, B.F, Peterson, F.C, Sundquist, W.I. | 登録日 | 2021-02-11 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release. J.Biol.Chem., 297, 2021
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7LP4
| Structure of Nedd4L WW3 domain | 分子名称: | E3 ubiquitin-protein ligase NEDD4-like | 著者 | Alam, S.L, Alian, A, Thompson, T, Rheinemann, L, Volkman, B.F, Peterson, F.C, Sundquist, W.I. | 登録日 | 2021-02-11 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release. J.Biol.Chem., 297, 2021
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2D2K
| Crystal Structure of a minimal, native (U39) all-RNA hairpin ribozyme | 分子名称: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | 登録日 | 2005-09-11 | 公開日 | 2005-11-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn Biochemistry, 44, 2005
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1X9C
| An all-RNA Hairpin Ribozyme with mutation U39C | 分子名称: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | 登録日 | 2004-08-20 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn. Biochemistry, 44, 2005
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1X7D
| Crystal Structure Analysis of Ornithine Cyclodeaminase Complexed with NAD and ornithine to 1.6 Angstroms | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-ornithine, ... | 著者 | Alam, S, Goodman, J.L, Wang, S, Ruzicka, F.J, Frey, P.A, Wedekind, J.E. | 登録日 | 2004-08-13 | 公開日 | 2004-11-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Ornithine Cyclodeaminase: Structure, Mechanism of Action, and Implications for
the u-Crystallin Family Biochemistry, 43, 2004
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1X9K
| An all-RNA Hairpin Ribozyme with mutation U39C | 分子名称: | 5'-R(*AP*AP*UP*AP*GP*AP*GP*AP*AP*GP*CP*GP*A)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*CP*AP*GP*UP*CP*CP*UP*AP*UP*U)-3', ... | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | 登録日 | 2004-08-21 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn. Biochemistry, 44, 2005
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2GA5
| yeast frataxin | 分子名称: | Frataxin homolog, mitochondrial | 著者 | He, Y, Alam, S.L, Proteasa, S.V, Zhang, Y, Lesuisse, E, Dancis, A. | 登録日 | 2006-03-07 | 公開日 | 2006-03-21 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Yeast Frataxin Solution Structure, Iron Binding and Ferrochelatase Interaction Biochemistry, 43, 2004
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3MO1
| Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment | 分子名称: | ACETATE ION, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ... | 著者 | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | 登録日 | 2010-04-22 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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3MOD
| Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced IgG) with 11 aa gp41 MPER-derived peptide | 分子名称: | ANTI-HIV-1 ANTIBODY 2F5 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 2F5 LIGHT CHAIN, gp41 MPER-derived peptide | 著者 | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | 登録日 | 2010-04-22 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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4RIS
| Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk | 分子名称: | CH58-UA Fab heavy chain, CH58-UA Fab light chain, Envelope glycoprotein | 著者 | Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. | 登録日 | 2014-10-07 | 公開日 | 2015-08-12 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015
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4RIR
| Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk | 分子名称: | CH58-UA Fab heavy chain, CH58-UA Fab light chain | 著者 | Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. | 登録日 | 2014-10-07 | 公開日 | 2015-08-12 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015
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4QF1
| Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ... | 著者 | Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F. | 登録日 | 2014-05-19 | 公開日 | 2015-02-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved. Immunity, 41, 2014
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5WA1
| CHMP4C A232T in complex with ALIX BRO1 | 分子名称: | Charged multivesicular body protein 4c, Programmed cell death 6-interacting protein | 著者 | Wenzel, D.M, Alam, S.L, Sundquist, W.I. | 登録日 | 2017-06-24 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | 主引用文献 | A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5DD1
| Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | 分子名称: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN | 著者 | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | 登録日 | 2015-08-24 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | 主引用文献 | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016
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5DD0
| Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | 分子名称: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide | 著者 | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | 登録日 | 2015-08-24 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.488 Å) | 主引用文献 | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016
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1O06
| Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM) | 分子名称: | Vacuolar protein sorting-associated protein VPS27, ZINC ION | 著者 | Fisher, R.D, Wang, B, Alam, S.L, Higginson, D.S, Rich, R, Myszka, D, Sundquist, W.I, Hill, C.P. | 登録日 | 2003-02-20 | 公開日 | 2003-07-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and ubiquitin binding of the ubiquitin-interacting motif. J.Biol.Chem., 278, 2003
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5EA0
| Structure of the antibody 7968 with human complement factor H-derived peptide | 分子名称: | Complement factor H-related protein 2, Heavy chain of antibody 7968 Fab fragment, Light chain of antibody 7968 Fab fragment | 著者 | Bushey, R.T, Moody, M.A, Nicely, N.I, Alam, S.M, Haynes, B.F, Winkler, M.T, Gottlin, E.B, Campa, M.J, Liao, H.-X, Patz Jr, E.F. | 登録日 | 2015-10-15 | 公開日 | 2016-05-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Therapeutic Antibody for Cancer, Derived from Single Human B Cells. Cell Rep, 15, 2016
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1VRE
| SOLUTION STRUCTURE OF COMPONENT IV GLYCERA DIBRANCHIATA MONOMERIC HEMOGLOBIN-CO | 分子名称: | CARBON MONOXIDE, PROTEIN (GLOBIN, MONOMERIC COMPONENT M-IV), ... | 著者 | Volkman, B.F, Alam, S.L, Satterlee, J.D, Markley, J.L. | 登録日 | 1999-03-25 | 公開日 | 1999-04-02 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and backbone dynamics of component IV Glycera dibranchiata monomeric hemoglobin-CO. Biochemistry, 37, 1998
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1VRF
| SOLUTION STRUCTURE OF COMPONENT IV GLYCERA DIBRANCHIATA MONOMERIC HEMOGLOBIN-CO | 分子名称: | CARBON MONOXIDE, PROTEIN (GLOBIN, MONOMERIC COMPONENT M-IV), ... | 著者 | Volkman, B.F, Alam, S.L, Satterlee, J.D, Markley, J.L. | 登録日 | 1999-03-25 | 公開日 | 1999-04-01 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and backbone dynamics of component IV Glycera dibranchiata monomeric hemoglobin-CO. Biochemistry, 37, 1998
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1NJ3
| Structure and Ubiquitin Interactions of the Conserved NZF Domain of Npl4 | 分子名称: | NPL4, ZINC ION | 著者 | Wang, B, Alam, S.L, Meyer, H.H, Payne, M, Stemmler, T.L, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-12-30 | 公開日 | 2003-04-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J.Biol.Chem., 278, 2003
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4WZX
| ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins | 分子名称: | COBALT (II) ION, IST1 homolog, SULFATE ION, ... | 著者 | Caballe, A, Wenzel, D.M, Agromayor, M, Alam, S.L, Skalicky, J.J, Kloc, M, Carlton, J.G, Labrador, L, Sundquist, W.I, Martin-Serrano, J. | 登録日 | 2014-11-20 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.3859 Å) | 主引用文献 | ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins. Elife, 4, 2015
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