1LUX
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![BU of 1lux by Molmil](/molmil-images/mine/1lux) | |
2KRZ
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2L9E
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![BU of 2l9e by Molmil](/molmil-images/mine/2l9e) | Solution Structure of the human Anti-codon Stem and loop(hASL) of transfer RNA Lysine 3 (tRNALys3) | Descriptor: | RNA (5'-R(*GP*CP*AP*GP*AP*CP*UP*(70U)P*UP*UP*(12A)P*AP*UP*CP*UP*GP*C)-3') | Authors: | Vendeix, F.A.P, Murphy IV, F.V, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F. | Deposit date: | 2011-02-08 | Release date: | 2011-03-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of the human Anti-codon Stem and loop(hASL) of transfer RNA Lysine 3 (tRNALys3) To be Published
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6DTI
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![BU of 6dti by Molmil](/molmil-images/mine/6dti) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an unmodifed anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin | Descriptor: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-06-16 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.54 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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229D
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![BU of 229d by Molmil](/molmil-images/mine/229d) | DNA ANALOG OF YEAST TRANSFER RNA PHE ANTICODON DOMAIN WITH MODIFIED BASES 5-METHYL CYTOSINE AND 1-METHYL GUANINE | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*AP*CP*(UMP)P*GP*AP*AP*(MG1)P*AP*(UMP)P*(5CM)P*(UMP)P*GP*G)-3') | Authors: | Basti, M.M, Stuart, J.W, Lam, A.T, Guenther, R, Agris, P.F. | Deposit date: | 1995-08-16 | Release date: | 1995-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Design, biological activity and NMR-solution structure of a DNA analogue of yeast tRNA(Phe) anticodon domain. Nat.Struct.Biol., 3, 1996
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6MPI
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![BU of 6mpi by Molmil](/molmil-images/mine/6mpi) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-10-07 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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6MKN
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![BU of 6mkn by Molmil](/molmil-images/mine/6mkn) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-09-25 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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6MPF
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![BU of 6mpf by Molmil](/molmil-images/mine/6mpf) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-10-05 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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2MX1
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![BU of 2mx1 by Molmil](/molmil-images/mine/2mx1) | Structure of the E. coli Threonylcarbamoyl-AMP Synthase TSAC | Descriptor: | Threonylcarbamoyl-AMP synthase | Authors: | Harris, K.A, Bobay, B.G, Sarachan, K.L, Sims, A.F, Bilbille, Y, Deutsch, C, Iwata-Reuyl, D, Agris, P.F. | Deposit date: | 2014-12-06 | Release date: | 2015-06-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions. J.Biol.Chem., 290, 2015
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1FEQ
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![BU of 1feq by Molmil](/molmil-images/mine/1feq) | NMR SOLUTION STRUCTURE OF THE ANTICODON OF TRNA(LYS3) WITH T6A MODIFICATION AT POSITION 37 | Descriptor: | 5'-R(*GP*CP*AP*GP*AP*CP*UP*UP*UP*UP*(T6A)P*AP*UP*CP*UP*GP*C)-3' | Authors: | Stuart, J.W, Gdaniec, Z, Guenther, R.H, Marszalek, M, Sochacka, E, Malkiewicz, A, Agris, P.F. | Deposit date: | 2000-07-21 | Release date: | 2000-11-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Functional anticodon architecture of human tRNALys3 includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t6A. Biochemistry, 39, 2000
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3T1Y
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![BU of 3t1y by Molmil](/molmil-images/mine/3t1y) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F. | Deposit date: | 2011-07-22 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. J.Mol.Biol., 416, 2012
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3T1H
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![BU of 3t1h by Molmil](/molmil-images/mine/3t1h) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin | Descriptor: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F. | Deposit date: | 2011-07-21 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. J.Mol.Biol., 416, 2012
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4GKJ
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![BU of 4gkj by Molmil](/molmil-images/mine/4gkj) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin. | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F. | Deposit date: | 2012-08-11 | Release date: | 2013-06-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.298 Å) | Cite: | Expanded use of sense codons is regulated by modified cytidines in tRNA. Proc.Natl.Acad.Sci.USA, 110, 2013
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1XMO
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![BU of 1xmo by Molmil](/molmil-images/mine/1xmo) | Crystal Structure of mnm5U34t6A37-tRNALysUUU Complexed with AAG-mRNA in the Decoding Center | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F. | Deposit date: | 2004-10-04 | Release date: | 2004-12-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | The role of modifications in codon discrimination by tRNA(Lys)(UUU). Nat.Struct.Mol.Biol., 11, 2004
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4GKK
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![BU of 4gkk by Molmil](/molmil-images/mine/4gkk) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUA-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F. | Deposit date: | 2012-08-11 | Release date: | 2013-06-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Expanded use of sense codons is regulated by modified cytidines in tRNA. Proc.Natl.Acad.Sci.USA, 110, 2013
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1XMQ
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![BU of 1xmq by Molmil](/molmil-images/mine/1xmq) | Crystal Structure of t6A37-ASLLysUUU AAA-mRNA Bound to the Decoding Center | Descriptor: | 16s ribosomal RNA, 30S Ribosomal Protein S10, 30S Ribosomal Protein S11, ... | Authors: | Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F. | Deposit date: | 2004-10-04 | Release date: | 2004-12-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The role of modifications in codon discrimination by tRNA(Lys)(UUU). Nat.Struct.Mol.Biol., 11, 2004
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1KOS
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![BU of 1kos by Molmil](/molmil-images/mine/1kos) | SOLUTION NMR STRUCTURE OF AN ANALOG OF THE YEAST TRNA PHE T STEM LOOP CONTAINING RIBOTHYMIDINE AT ITS NATURALLY OCCURRING POSITION | Descriptor: | 5'-R(*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*(CH)P*CP*AP*CP*AP*G)- 3' | Authors: | Koshlap, K.M, Guenther, R, Sochacka, E, Malkiewicz, A, Agris, P.F. | Deposit date: | 1999-05-03 | Release date: | 1999-10-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | A distinctive RNA fold: the solution structure of an analogue of the yeast tRNAPhe T Psi C domain. Biochemistry, 38, 1999
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1LUU
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![BU of 1luu by Molmil](/molmil-images/mine/1luu) | |
2UU9
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![BU of 2uu9 by Molmil](/molmil-images/mine/2uu9) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUG-codon in the A-site and paromomycin. | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nat. Struct. Mol. Biol., 14, 2007
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2UUC
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![BU of 2uuc by Molmil](/molmil-images/mine/2uuc) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin. | Descriptor: | 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nat. Struct. Mol. Biol., 14, 2007
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2UUB
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![BU of 2uub by Molmil](/molmil-images/mine/2uub) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUU-codon in the A-site and paromomycin. | Descriptor: | 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism for Expanding the Decoding Capacity of Transfer Rnas by Modification of Uridines Nat.Struct.Mol.Biol., 14, 2007
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2UUA
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![BU of 2uua by Molmil](/molmil-images/mine/2uua) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin. | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nat. Struct. Mol. Biol., 14, 2007
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2JR4
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![BU of 2jr4 by Molmil](/molmil-images/mine/2jr4) | NMR Solution Structure of the Anticodon of E.coli TRNA-VAL3 With no Modifications | Descriptor: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*UP*AP*CP*AP*AP*GP*GP*AP*GP*G)-3' | Authors: | Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | Deposit date: | 2007-06-20 | Release date: | 2007-07-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding. Biochemistry, 47, 2008
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2JRQ
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![BU of 2jrq by Molmil](/molmil-images/mine/2jrq) | NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 1 modification (cmo5U34) | Descriptor: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*AP*AP*GP*GP*AP*GP*G)-3' | Authors: | Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | Deposit date: | 2007-06-28 | Release date: | 2007-07-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Wobble-Position Modifications Pre-structure tRNA's Anticodon for Ribosome-Mediated Codon Binding To be Published
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2JRG
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![BU of 2jrg by Molmil](/molmil-images/mine/2jrg) | NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 2 modifications (cmo5U34 M6A37) | Descriptor: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*(6MZ)P*AP*GP*GP*AP*GP*G)-3' | Authors: | Vendeix, F.A, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | Deposit date: | 2007-06-26 | Release date: | 2007-07-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding. Biochemistry, 47, 2008
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