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PDB: 356 件

4CH5
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Structure of pyrrolysyl-tRNA synthetase in complex with adenylated propionyl lysine
分子名称: (S)-2-amino-6-propionamidohexanoic(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
著者Fluegel, V, Vrabel, M, Schneider, S.
登録日2013-11-28
公開日2014-03-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins.
Plos One, 9, 2014
4CH3
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Structure of pyrrolysyl-tRNA synthetase in complex with adenylated butyryl lysine
分子名称: 1,2-ETHANEDIOL, 5'-O-({[(2R)-2-amino-6-(butanoylamino)hexanoyl]oxy}phosphinato)adenosine, MAGNESIUM ION, ...
著者Fluegel, V, Vrabel, M, Schneider, S.
登録日2013-11-28
公開日2014-03-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins.
Plos One, 9, 2014
1OSB
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Conjugative Relaxase TrwC in complex with OriT Dna. Metal-free structure.
分子名称: Dna oligonucleotide, SULFATE ION, TrwC protein
著者Guasch, A, Lucas, M, Moncalian, G, Cabezas, M, Perez-Luque, R, Gomis-Ruth, F.X, de la Cruz, F, Coll, M.
登録日2003-03-19
公開日2003-11-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.
Nat.Struct.Biol., 10, 2003
2HZ9
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Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-08
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
4YOL
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Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
著者Xia, X, Blaber, M.
登録日2015-03-11
公開日2016-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.
J.Pharm.Sci., 105, 2016
5AHV
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Cryo-EM structure of helical ANTH and ENTH tubules on PI(4,5)P2-containing membranes
分子名称: ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2, ENTH DOMAIN OF EPSIN ENT1
著者Skruzny, M, Desfosses, A, Prinz, S, Dodonova, S.O, Gieras, A, Uetrecht, C, Jakobi, A.J, Abella, M, Hagen, W.J.H, Schulz, J, Meijers, R, Rybin, V, Briggs, J.A.G, Sachse, C, Kaksonen, M.
登録日2015-02-10
公開日2015-05-06
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (13.6 Å)
主引用文献An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
2N7H
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Hybrid structure of the Type 1 Pilus of Uropathogenic E.coli
分子名称: FimA
著者Habenstein, B, Loquet, A, Giller, K, Vasa, S, Becker, S, Habeck, M, Lange, A.
登録日2015-09-11
公開日2015-09-23
最終更新日2015-10-14
実験手法SOLID-STATE NMR
主引用文献Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Angew.Chem.Int.Ed.Engl., 54, 2015
4CH6
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Structure of pyrrolysyl-tRNA synthetase in complex with adenylated propargyloxycarbonyl lysine
分子名称: (S)-2-amino-6-(((prop-2-yn-1-yloxy)carbonyl)amino)hexanoic (((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric)anhydride, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
著者Fluegel, V, Vrabel, M, Schneider, S.
登録日2013-11-28
公開日2014-03-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins.
Plos One, 9, 2014
4AB7
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Crystal structure of a tetrameric acetylglutamate kinase from Saccharomyces cerevisiae complexed with its substrate N- acetylglutamate
分子名称: N-ACETYL-L-GLUTAMATE, PROTEIN ARG5,6, MITOCHONDRIAL
著者de Cima, S, Gil-Ortiz, F, Crabeel, M, Fita, I, Rubio, V.
登録日2011-12-07
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Insight on an Arginine Synthesis Metabolon from the Tetrameric Structure of Yeast Acetylglutamate Kinase
Plos One, 7, 2012
1YBJ
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Structural and Dynamics studies of both apo and holo forms of the hemophore HasA
分子名称: Hemophore HasA
著者Wolff, N, Izadi-Pruneyre, N, Couprie, J, Habeck, M, Linge, J, Rieping, W, Wandersman, C, Nilges, M, Delepierre, M, Lecroisey, A.
登録日2004-12-21
公開日2005-12-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications.
J.Mol.Biol., 376, 2008
4QKR
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Crystal Structure of 6xTyr/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22Y/L44Y/L64Y/L85Y/L108Y/L132Y, Primitive Version 2)
分子名称: DE NOVO PROTEIN 6XTYR/PV2, IMIDAZOLE
著者Longo, L.M, Blaber, M, Tenorio, C.A.
登録日2014-06-09
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.746 Å)
主引用文献A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding.
Protein Sci., 24, 2015
4Q91
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Crystal structure of C16A/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
分子名称: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION
著者Xia, X, Blaber, M.
登録日2014-04-28
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4CH4
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Structure of pyrrolysyl-tRNA synthetase in complex with adenylated crotonyl lysine
分子名称: 1,2-ETHANEDIOL, 5'-O-[({(2R)-2-amino-6-[(2E)-but-2-enoylamino]hexanoyl}oxy)phosphinato]adenosine, MAGNESIUM ION, ...
著者Fluegel, V, Vrabel, M, Schneider, S.
登録日2013-11-28
公開日2014-03-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins.
Plos One, 9, 2014
2HWA
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Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HW9
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Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWM
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BU of 2hwm by Molmil
Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
4QKS
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Crystal Structure of 6xTrp/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22W/L44W/L64W/L85W/L108W/L132W his Primitive Version 2)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DE NOVO PROTEIN 6XTRP/PV2, SULFATE ION
著者Longo, L.M, Tenorio, C.A, Blaber, M.
登録日2014-06-09
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding.
Protein Sci., 24, 2015
1KWF
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Atomic Resolution Structure of an Inverting Glycosidase in Complex with Substrate
分子名称: Endoglucanase A, beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Guerin, D.M.A, Lascombe, M.-B, Costabel, M, Souchon, H, Lamzin, V, Beguin, P, Alzari, P.M.
登録日2002-01-29
公開日2002-03-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (0.94 Å)
主引用文献Atomic (0.94 A) resolution structure of an inverting glycosidase in complex with substrate.
J.Mol.Biol., 316, 2002
3C7C
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A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH-L-Arginine)
分子名称: ARGININE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Octopine dehydrogenase
著者Smits, S.H.J, Mueller, A, Schmitt, L, Grieshaber, M.K.
登録日2008-02-07
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus.
J.Mol.Biol., 381, 2008
1M16
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Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).
分子名称: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M.
登録日2002-06-17
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
3CRG
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Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala
分子名称: FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ...
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
1IQ8
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Crystal Structure of archaeosine tRNA-guanine transglycosylase from Pyrococcus horikoshii
分子名称: ARCHAEOSINE TRNA-GUANINE TRANSGLYCOSYLASE, MAGNESIUM ION, ZINC ION
著者Ishitani, R, Nureki, O, Fukai, S, Kijimoto, T, Nameki, N, Watanabe, M, Kondo, H, Sekine, M, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2001-07-09
公開日2002-05-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of archaeosine tRNA-guanine transglycosylase.
J.Mol.Biol., 318, 2002
1YTO
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Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-02-10
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
1UAW
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Solution structure of the N-terminal RNA-binding domain of mouse Musashi1
分子名称: mouse-musashi-1
著者Miyanoiri, Y, Kobayashi, H, Watanabe, M, Ikeda, T, Nagata, T, Okano, H, Uesugi, S, Katahira, M.
登録日2003-03-24
公開日2004-03-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics
J.Biol.Chem., 278, 2003
1S6M
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Conjugative Relaxase Trwc In Complex With Orit DNA. Metal-Bound Structure
分子名称: DNA (25-MER), NICKEL (II) ION, TrwC
著者Guasch, A, Lucas, M, Moncalian, G, Cabezas, M, Perez-Luque, R, Gomis-Ruth, F.X, de la Cruz, F, Coll, M.
登録日2004-01-26
公開日2005-06-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site.
J.Mol.Biol., 358, 2006

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