4CH5

Structure of pyrrolysyl-tRNA synthetase in complex with adenylated propionyl lysine

Summary for 4CH5

• Entry DOI: 10.2210/pdb4ch5/pdb
• Related: 4CH3 4CH4 4CH6
• Descriptor: PYRROLYSINE--TRNA LIGASE, (S)-2-amino-6-propionamidohexanoic(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: ligase, non-natural amino acid, pyrrolysine
• Biological source: METHANOSARCINA MAZEI
• Total number of polymer chains: 1
• Total formula weight: 34458.29

Authors

Fluegel, V.,Vrabel, M.,Schneider, S. (deposition date: 2013-11-28, release date: 2014-03-19, Last modification date: 2023-12-20)

• Primary citation: Flugel, V.,Vrabel, M.,Schneider, S.; Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins.; Plos One, 9:96198-, 2014; PubMed: 24760130; DOI: 10.1371/JOURNAL.PONE.0096198

Experimental method

X-RAY DIFFRACTION (2.2 Å)