4IV9
 
 | | Structure of the Flavoprotein Tryptophan-2-Monooxygenase | | Descriptor: | 1,2-ETHANEDIOL, 2-(1H-INDOL-3-YL)ACETAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Gaweska, H.M, Taylor, A.B, Hart, P.J, Fitzpatrick, P.F. | | Deposit date: | 2013-01-22 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Structure of the flavoprotein tryptophan 2-monooxygenase, a key enzyme in the formation of galls in plants.
Biochemistry, 52, 2013
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4JHZ
 | | Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide | | Descriptor: | 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide, Beta-glucuronidase | | Authors: | Roberts, A.B, Wallace, B.D, Redinbo, M.R. | | Deposit date: | 2013-03-05 | | Release date: | 2013-08-28 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.831 Å) | | Cite: | Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity.
Mol.Pharmacol., 84, 2013
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4JDO
 | | Secreted chlamydial protein pgp3, coiled-coil deletion | | Descriptor: | SODIUM ION, Virulence plasmid protein pGP3-D | | Authors: | Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J. | | Deposit date: | 2013-02-25 | | Release date: | 2013-06-05 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
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4K2E
 | | HlyU from Vibrio cholerae N16961 | | Descriptor: | Transcriptional activator HlyU | | Authors: | Mukherjee, D, Datta, A.B, Chakrabarti, P. | | Deposit date: | 2013-04-09 | | Release date: | 2014-04-30 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications.
Biochim.Biophys.Acta, 1844, 2014
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4K89
 | | Crystal structure of Pseudomonas aeruginosa strain K solvent tolerant elastase | | Descriptor: | CALCIUM ION, GLYCEROL, Organic solvent tolerant elastase, ... | | Authors: | Ali, M.S.M, Said, Z.S.A.M, Rahman, R.N.Z.R.A, Basri, M, Salleh, A.B. | | Deposit date: | 2013-04-18 | | Release date: | 2014-05-21 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Crystal structure analysia of solvent tolerant elastase strain K
To be Published
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4L19
 | | Matrix metalloproteinase-13 complexed with selective inhibitor compound Q1 | | Descriptor: | 2-[(4-methylbenzyl)sulfanyl]-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one, CALCIUM ION, Collagenase 3, ... | | Authors: | Minond, D, Spicer, T.P, Jiang, J, Taylor, A.B, Hart, P.J, Roush, W.R, Fields, G.B, Hodder, P.S. | | Deposit date: | 2013-06-02 | | Release date: | 2014-12-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro.
J.Med.Chem., 57, 2014
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4L1L
 | | Rat PKC C2 domain bound to CD | | Descriptor: | CADMIUM ION, Protein kinase C alpha type, SULFATE ION | | Authors: | Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I. | | Deposit date: | 2013-06-03 | | Release date: | 2013-08-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional.
J.Am.Chem.Soc., 135, 2013
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4JDM
 | | Secreted Chlamydial Protein PGP3, full-length | | Descriptor: | Virulence plasmid protein pGP3-D | | Authors: | Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J. | | Deposit date: | 2013-02-25 | | Release date: | 2013-06-05 | | Last modified: | 2013-10-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
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4MCM
 | | Human SOD1 C57S Mutant, As-isolated | | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | | Authors: | Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S. | | Deposit date: | 2013-08-21 | | Release date: | 2014-08-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.
J.Biol.Chem., 290, 2015
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4JDN
 | | Secreted Chlamydial Protein PGP3, C-terminal Domain | | Descriptor: | GLYCEROL, POTASSIUM ION, Virulence plasmid protein pGP3-D | | Authors: | Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J. | | Deposit date: | 2013-02-25 | | Release date: | 2013-06-05 | | Last modified: | 2013-10-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
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4K1C
 | | VCX1 Calcium/Proton Exchanger | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, IODIDE ION, ... | | Authors: | Waight, A.B, Pedersen, B.P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | | Deposit date: | 2013-04-04 | | Release date: | 2013-05-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for alternating access of a eukaryotic calcium/proton exchanger.
Nature, 499, 2013
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8UT4
 | | CryoEM structure of A/Michigan/45/2015 H1 in complex with flu HA central stem VH1-18 antibody 09-1B12 | | Descriptor: | 09-1B12 HC Fv, 09-1B12 LC Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Huang, J, Han, J, Ward, A.B. | | Deposit date: | 2023-10-30 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
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8U53
 | | Mechanically activated ion channel OSCA3.1 in nanodiscs | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CSC1-like protein ERD4, PALMITIC ACID, ... | | Authors: | Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | | Deposit date: | 2023-09-12 | | Release date: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli.
Elife, 12, 2024
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8UTT
 | | KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | Authors: | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | Deposit date: | 2023-10-31 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
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8UT5
 | | CryoEM structure of A/Michigan/45/2015 H1 in complex with flu HA central stem VH1-18 antibody UCA6_N55T | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | Authors: | Huang, J, Han, J, Ward, A.B. | | Deposit date: | 2023-10-30 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
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8VFV
 | | HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B16_d77.5 mouse Fab heavy chain Fv, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2023-12-22 | | Release date: | 2024-05-15 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies.
Science, 384, 2024
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8VY6
 | | Murine light chain dimer | | Descriptor: | 6A8 light chain, SULFATE ION | | Authors: | Kapingidza, A.B, Dolamore, C, Hyduke, N.P, Easly, W, Chivv, C, Pomes, A, Chruszcz, M. | | Deposit date: | 2024-02-07 | | Release date: | 2024-07-03 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural, Biophysical, and Computational Studies of a Murine Light Chain Dimer.
Molecules, 29, 2024
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8UTY
 | | KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | Authors: | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | Deposit date: | 2023-10-31 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
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8UTV
 | | KIF1A[1-393] P305L mutant ADP bound in complex with a microtubule | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | Deposit date: | 2023-10-31 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
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8UT7
 | | CryoEM structure of A/Perth/16/2009 H3 in complex with polyclonal Fab from mice immunized with H3 stem nanoparticles-28 days post immunization | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H3D28 pFab HC Fv_polyA, ... | | Authors: | Huang, J, Han, J, Ward, A.B. | | Deposit date: | 2023-10-30 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
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8UTU
 | | KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | Authors: | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | Deposit date: | 2023-10-31 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
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8UT9
 | | CryoEM structure of A/Shanghai/1/2013 H7 in complex with polyclonal Fab from mice immunized with H7 stem nanoparticles-28 days post immunization | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Huang, J, Han, J, Ward, A.B. | | Deposit date: | 2023-10-30 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
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8U44
 | | CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06 | | Descriptor: | 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Moore, N, Han, J, Ward, A.B, Wilson, I.A. | | Deposit date: | 2023-09-08 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published
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8UTR
 | | KIF1A[1-393] ADP bound in complex with a microtubule | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | Deposit date: | 2023-10-31 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
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8UT6
 | | CryoEM structure of A/Perth/16/2009 H3 in complex with polyclonal Fab from mice immunized with H3 stem nanoparticles-15 days post immunization | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H3D15 pFab HC Fv_polyA, ... | | Authors: | Huang, J, Han, J, Ward, A.B. | | Deposit date: | 2023-10-30 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
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