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PDB: 1498 件

6UGP
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Human Carbonic Anhydrase 2 complexed with SB4-206
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-chloro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ...
著者Murray, A.B, Lomelino, C.L, McKenna, R.
登録日2019-09-26
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.306 Å)
主引用文献"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
J.Med.Chem., 63, 2020
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
分子名称: T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFK
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De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
分子名称: BG505-SOSIP-T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
分子名称: O43_dn18A, O43_dn18B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2020-08-19
実験手法ELECTRON MICROSCOPY (4.54 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFL
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BU of 6vfl by Molmil
BG505-SOSIP model reconstructed by subparticle extraction and refinement from a tetrahedral nanoparticle T33_dn10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIPv5.2(7S) - gp120, ...
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2020-08-26
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6V8O
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BU of 6v8o by Molmil
RSC core
分子名称: Chromatin structure-remodeling complex protein RSC14, Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, ...
著者Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E.
登録日2019-12-11
公開日2020-01-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
Elife, 8, 2019
6UYE
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BU of 6uye by Molmil
EBOV GPdMuc Makona bound to rEBOV-548 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ...
著者Murin, C.D, Ward, A.B.
登録日2019-11-13
公開日2020-03-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
6UUY
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BU of 6uuy by Molmil
Schistosoma haematobium (Blood Fluke) Sulfotransferase/Hycanthone Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-3'-5'-DIPHOSPHATE, BICINE, ...
著者Taylor, A.B.
登録日2019-11-01
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Molecular basis for hycanthone drug action in schistosome parasites.
Mol.Biochem.Parasitol., 236, 2020
6V92
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BU of 6v92 by Molmil
RSC-NCP
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC14, ...
著者Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E.
登録日2019-12-13
公開日2020-01-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
Elife, 8, 2019
6VO3
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BU of 6vo3 by Molmil
AMC009 SOSIP.v4.2 in complex with PGV04 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ...
著者Cottrell, C.A, de Val, N, Ward, A.B.
登録日2020-01-29
公開日2020-09-23
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.
J.Virol., 94, 2020
6VL5
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BU of 6vl5 by Molmil
BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
著者Ward, A.B, Antanasijevic, A.
登録日2020-01-22
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
NPJ Vaccines, 5, 2020
6VU5
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BU of 6vu5 by Molmil
Structure of G-alpha-q bound to its chaperone Ric-8A
分子名称: Guanine nucleotide-binding protein G(q) subunit alpha, Resistance to inhibitors of cholinesterase-8A (Ric-8A)
著者Seven, A.B, Hilger, D.
登録日2020-02-14
公開日2020-03-18
最終更新日2020-03-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of G alpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.
Cell Rep, 30, 2020
7L87
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BU of 7l87 by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.32034 (Wk26 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
著者Antanasijevic, A, Sewall, L.M, Yang, Y.R, Perrett, H.R, Ward, A.B.
登録日2020-12-31
公開日2021-08-04
最終更新日2021-11-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8X
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BU of 7l8x by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-4 from animal Rh.33311 (Wk26 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
著者Antanasijevic, A, Sewall, L.M, Yang, Y.R, Ward, A.B.
登録日2021-01-01
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L90
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BU of 7l90 by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-8 from animal Rh.33311 (Wk26 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
著者Antanasijevic, A, Sewall, L.M, Ward, A.B.
登録日2021-01-01
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L86
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BU of 7l86 by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.32034 (Wk26 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
著者Antanasijevic, A, Sewall, L.M, Ward, A.B.
登録日2020-12-31
公開日2021-08-04
最終更新日2021-11-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8E
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BU of 7l8e by Molmil
BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-1 from animal Rh.33172 (Wk38 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Antanasijevic, A, Sewall, L.M, Ward, A.B.
登録日2020-12-31
公開日2021-08-04
最終更新日2021-09-08
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8F
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BU of 7l8f by Molmil
BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-2 from animal Rh.33172 (Wk38 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Antanasijevic, A, Sewall, L.M, Ward, A.B.
登録日2020-12-31
公開日2021-08-04
最終更新日2021-09-08
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7LUP
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BU of 7lup by Molmil
Human TRiC/CCT complex with reovirus outer capsid protein sigma-3
分子名称: Outer capsid protein sigma-3, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S.
登録日2021-02-22
公開日2021-03-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LUM
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BU of 7lum by Molmil
Human TRiC in ATP/AlFx closed state
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S.
登録日2021-02-22
公開日2021-03-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LVR
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BU of 7lvr by Molmil
KIF14[391-743] - ADP-AlFx closed state class in complex with a microtubule
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H.
登録日2021-02-26
公開日2021-05-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Nat Commun, 12, 2021
7LVQ
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BU of 7lvq by Molmil
KIF14[391-743] - AMP-PNP closed state class in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF14, ...
著者Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H.
登録日2021-02-26
公開日2021-05-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Nat Commun, 12, 2021
7LH6
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BU of 7lh6 by Molmil
The structure of Bacteroides plebeius L-galactose dehydrogenase
分子名称: L-galactose dehydrogenase
著者Robb, C.S, Pluvinage, B, Vickers, C, Boraston, A.B.
登録日2021-01-21
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LHA
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BU of 7lha by Molmil
Structure of the Exo-L-galactose-6-sulfatase BuS1_11 from Bacteroides uniformis
分子名称: CALCIUM ION, Exo-L-galactose-6-sulfatase, NICKEL (II) ION
著者Robb, C.S, Boraston, A.B.
登録日2021-01-21
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LJJ
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Structure of the Exo-alpha-L-galactosidase BpGH29 from Bacteroides plebeius
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Exo-alpha-L-galactosidase
著者Robb, C.S, Boraston, A.B.
登録日2021-01-29
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022

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件を2024-07-24に公開中

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