6VL5

BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2

Summary for 6VL5

• Entry DOI: 10.2210/pdb6vl5/pdb
• EMDB information: 21230
• Descriptor: BG505 SOSIP.v5.2(7S) - gp120, BG505 SOSIP.v5.2(7S) - gp41, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: hiv env, de novo, nanoparticles, vaccine design, de novo protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 6
• Total formula weight: 249489.18

Authors

Ward, A.B.,Antanasijevic, A. (deposition date: 2020-01-22, release date: 2020-08-12, Last modification date: 2020-09-02)

• Primary citation: Martin, J.T.,Cottrell, C.A.,Antanasijevic, A.,Carnathan, D.G.,Cossette, B.J.,Enemuo, C.A.,Gebru, E.H.,Choe, Y.,Viviano, F.,Fischinger, S.,Tokatlian, T.,Cirelli, K.M.,Ueda, G.,Copps, J.,Schiffner, T.,Menis, S.,Alter, G.,Schief, W.R.,Crotty, S.,King, N.P.,Baker, D.,Silvestri, G.,Ward, A.B.,Irvine, D.J.; Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.; NPJ Vaccines, 5:72-72, 2020; PubMed: 32802411; DOI: 10.1038/s41541-020-00223-1

Experimental method

ELECTRON MICROSCOPY (4.5 Å)