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PDB: 1498 件

7RMI
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SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A.
登録日2021-07-27
公開日2021-11-03
最終更新日2022-01-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
7RMG
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Substance P bound to active human neurokinin 1 receptor in complex with miniGs/q70
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A.
登録日2021-07-27
公開日2021-11-03
最終更新日2022-01-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
7RMH
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Substance P bound to active human neurokinin 1 receptor in complex with miniGs399
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A.
登録日2021-07-27
公開日2021-11-03
最終更新日2022-01-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
1Q35
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Crystal Structure of Pasteurella haemolytica Apo Ferric ion-Binding Protein A
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, iron binding protein FbpA
著者Shouldice, S.R, Dougan, D.R, Skene, R.J, Snell, G, Scheibe, D, Williams, P.A, Kirby, S, McRee, D.E, Schryvers, A.B, Tari, L.W.
登録日2003-07-28
公開日2003-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structure of Pasteurella haemolytica ferric ion-binding protein A reveals a novel class of bacterial iron-binding proteins
J.Biol.Chem., 278, 2003
1Q0Y
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Anti-Morphine Antibody 9B1 Complexed with Morphine
分子名称: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, Fab 9B1, Heavy chain, ...
著者Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D.
登録日2003-07-17
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
1Q0X
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Anti-morphine Antibody 9B1 Unliganded Form
分子名称: Fab 9B1, heavy chain, light chain, ...
著者Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D.
登録日2003-07-17
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
1RF8
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Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ...
著者Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G.
登録日2003-11-07
公開日2003-12-23
最終更新日2024-03-06
実験手法SOLUTION NMR
主引用文献Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell(Cambridge,Mass.), 115, 2003
7S6I
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SARS-CoV-2-6P-Mut2 S protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6J
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J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6L
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BU of 7s6l by Molmil
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S6K
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BU of 7s6k by Molmil
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2021-09-14
公開日2022-05-11
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RU4
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BU of 7ru4 by Molmil
CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.33 IgG heavy chain Fv, ...
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2021-08-16
公開日2022-08-24
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Iscience, 25, 2022
7RU1
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SARS-CoV-2-6P-Mut7 S protein (C3 symmetry)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Iscience, 25, 2022
7RU8
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CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.30 Fab Kappa chain Fv, ...
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2021-08-16
公開日2022-08-24
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Iscience, 25, 2022
7RU3
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CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2021-08-16
公開日2022-08-24
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Iscience, 25, 2022
7RU2
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SARS-CoV-2-6P-Mut7 S protein (asymmetric)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Iscience, 25, 2022
7RU5
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BU of 7ru5 by Molmil
CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.30 Fab heavy chain Fv, ...
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Iscience, 25, 2022
2O4E
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The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens
分子名称: O-GlcNAcase nagJ
著者Chitayat, S, Adams, J.J, Gregg, K, Boraston, A.B, Smith, S.P.
登録日2006-12-04
公開日2007-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of a putative non-cellulosomal cohesin module from a Clostridium perfringens family 84 glycoside hydrolase.
J.Mol.Biol., 375, 2008
7SGF
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BU of 7sgf by Molmil
Lassa virus glycoprotein construct (Josiah GPC-I53-50A) in complex with LAVA01 antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Antanasijevic, A, Brouwer, P.J.M, Ward, A.B.
登録日2021-10-05
公開日2022-10-12
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (4.41 Å)
主引用文献Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.
Cell Host Microbe, 30, 2022
7SGE
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I53-50 nanoparticle core reconstructed from GPC-I53-50NP by focused refinement
分子名称: I53-50B component, Josiah GPCysR4-I53-50A - nanoparticle component
著者Antanasijevic, A, Brouwer, P.J.M, Ward, A.B.
登録日2021-10-05
公開日2022-10-12
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.
Cell Host Microbe, 30, 2022
7SGD
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BU of 7sgd by Molmil
Lassa virus glycoprotein construct(Josiah GPCysR4) recovered from GPC-I53-50 nanoparticle by localized reconstruction
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Antanasijevic, A, Brouwer, P.J.M, Ward, A.B.
登録日2021-10-05
公開日2022-10-12
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.
Cell Host Microbe, 30, 2022
1OFN
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BU of 1ofn by Molmil
Purification, crystallisation and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis; the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway.
分子名称: GLYCEROL, PCZA361.16
著者Merkel, A.B, Naismith, J.H.
登録日2003-04-17
公開日2004-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Purification, Crystallization and Preliminary Structural Studies of Dtdp-4-Keto-6-Deoxy-Glucose-5-Epimerase (Evad) from Amycolatopsis Orientalis, the Fourth Enzyme in the Dtdp-L-Epivancosamine Biosynthetic Pathway.
Acta Crystallogr.,Sect.D, 58, 2002
1OQG
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BU of 1oqg by Molmil
Crystal structure of the D63E mutant of the N-lobe human transferrin
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, Baker, E.N.
登録日2003-03-09
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin
Biochemistry, 42, 2003
1RYO
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BU of 1ryo by Molmil
Human serum transferrin, N-lobe bound with oxalate
分子名称: FE (III) ION, OXALATE ION, Serotransferrin
著者Halbrooks, P.J, Mason, A.B, Adams, T.E, Briggs, S.K, Everse, S.J.
登録日2003-12-22
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The oxalate effect on release of iron from human serum transferrin explained.
J.Mol.Biol., 339, 2004
2UVE
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BU of 2uve by Molmil
Structure of Yersinia enterocolitica Family 28 Exopolygalacturonase
分子名称: ACETATE ION, EXOPOLYGALACTURONASE, NICKEL (II) ION, ...
著者Abbott, D.W, Boraston, A.B.
登録日2007-03-09
公開日2007-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The Structural Basis for Exopolygalacturonase Activity in a Family 28 Glycoside Hydrolase.
J.Mol.Biol., 368, 2007

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