7RU4

CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement)

Summary for 7RU4

• Entry DOI: 10.2210/pdb7ru4/pdb
• EMDB information: 24696
• Descriptor: CC6.33 IgG heavy chain Fv, CC6.33 IgG kappa chain Fv, Spike glycoprotein, ... (5 entities in total)
• Functional Keywords: covid, sars-cov-2, stabilizing mutations, neutralizing antibody, rbd, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 166584.50

Authors

Ozorowski, G.,Turner, H.L.,Ward, A.B. (deposition date: 2021-08-16, release date: 2022-08-24, Last modification date: 2022-09-14)

• Primary citation: Zhao, F.,Keating, C.,Ozorowski, G.,Shaabani, N.,Francino-Urdaniz, I.M.,Barman, S.,Limbo, O.,Burns, A.,Zhou, P.,Ricciardi, M.J.,Woehl, J.,Tran, Q.,Turner, H.L.,Peng, L.,Huang, D.,Nemazee, D.,Andrabi, R.,Sok, D.,Teijaro, J.R.,Whitehead, T.A.,Ward, A.B.,Burton, D.R.,Jardine, J.G.; Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.; Iscience, 25:104914-104914, 2022; PubMed: 35971553; DOI: 10.1016/j.isci.2022.104914

Experimental method

ELECTRON MICROSCOPY (3.3 Å)