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PDB: 1498 件

6B54
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Schistosoma haematobium (Blood Fluke) Sulfotransferase/Oxamniquine Complex, S166T Mutant
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol
著者Taylor, A.B.
登録日2017-09-27
公開日2018-10-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?
Int.J.Parasitol., 2020
2O7U
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BU of 2o7u by Molmil
Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N.
登録日2006-12-11
公開日2007-01-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
Acta Crystallogr.,Sect.D, 63, 2007
6AZA
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BU of 6aza by Molmil
NMR structure of sea anemone toxin Kappa-actitoxin-Ate1a
分子名称: ARG-CYS-LYS-THR-CYS-SER-LYS-GLY-ARG-CYS-ARG-PRO-LYS-PRO-ASN-CYS-GLY-NH2
著者Chin, Y.K.-Y, Madio, B, King, G.F, Undheim, E.A.B.
登録日2017-09-10
公開日2018-09-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold.
Cell. Mol. Life Sci., 75, 2018
6UGP
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BU of 6ugp by Molmil
Human Carbonic Anhydrase 2 complexed with SB4-206
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-chloro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ...
著者Murray, A.B, Lomelino, C.L, McKenna, R.
登録日2019-09-26
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.306 Å)
主引用文献"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
J.Med.Chem., 63, 2020
1RDT
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BU of 1rdt by Molmil
Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer
分子名称: (S)-(2E)-3[4-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)TETRAHYDRO-1-BENZOFURAN-2-YL]-2-PROPENOIC ACID, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, LxxLL motif coactivator, ...
著者Haffner, C.D, Lenhard, J.M, Miller, A.B, McDougald, D.L, Dwornik, K, Ittoop, O.R, Gampe Jr, R.T, Xu, H.E, Blanchard, S, Montana, V.G.
登録日2003-11-06
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based design of potent retinoid X receptor alpha agonists.
J.Med.Chem., 47, 2004
1Q35
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Crystal Structure of Pasteurella haemolytica Apo Ferric ion-Binding Protein A
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, iron binding protein FbpA
著者Shouldice, S.R, Dougan, D.R, Skene, R.J, Snell, G, Scheibe, D, Williams, P.A, Kirby, S, McRee, D.E, Schryvers, A.B, Tari, L.W.
登録日2003-07-28
公開日2003-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structure of Pasteurella haemolytica ferric ion-binding protein A reveals a novel class of bacterial iron-binding proteins
J.Biol.Chem., 278, 2003
5YWR
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BU of 5ywr by Molmil
Crystal Structure of RING E3 ligase ZNRF1 in complex with Ube2N (Ubc13)
分子名称: E3 ubiquitin-protein ligase ZNRF1, FORMIC ACID, TRIETHYLENE GLYCOL, ...
著者Behera, A.P, Naskar, P, Datta, A.B.
登録日2017-11-30
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.
Biochem. J., 475, 2018
1Q0Y
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BU of 1q0y by Molmil
Anti-Morphine Antibody 9B1 Complexed with Morphine
分子名称: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, Fab 9B1, Heavy chain, ...
著者Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D.
登録日2003-07-17
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
1Q0X
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Anti-morphine Antibody 9B1 Unliganded Form
分子名称: Fab 9B1, heavy chain, light chain, ...
著者Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D.
登録日2003-07-17
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
分子名称: T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFK
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De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
分子名称: BG505-SOSIP-T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6APO
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BU of 6apo by Molmil
Anti-Marburgvirus Nucleoprotein Single Domain Antibody A
分子名称: Anti-Marburgvirus Nucleoprotein Single Domain Antibody A
著者Taylor, A.B, Garza, J.A.
登録日2017-08-17
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.168 Å)
主引用文献Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies.
Front Immunol, 8, 2017
6AWB
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BU of 6awb by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state
分子名称: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
著者Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
登録日2017-09-05
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6B52
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BU of 6b52 by Molmil
Schistosoma haematobium (Blood Fluke) Sulfotransferase/Oxamniquine Complex, Y54F Mutant
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol
著者Taylor, A.B.
登録日2017-09-27
公開日2018-10-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?
Int.J.Parasitol., 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
分子名称: O43_dn18A, O43_dn18B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2020-08-19
実験手法ELECTRON MICROSCOPY (4.54 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFL
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BU of 6vfl by Molmil
BG505-SOSIP model reconstructed by subparticle extraction and refinement from a tetrahedral nanoparticle T33_dn10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIPv5.2(7S) - gp120, ...
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2020-08-26
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6AWD
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BU of 6awd by Molmil
Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
登録日2017-09-05
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6B0C
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BU of 6b0c by Molmil
KLP10A-AMPPNP in complex with curved tubulin and a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp10A, ...
著者Benoit, M.P.M.H, Asenjo, A.B, Sosa, H.
登録日2017-09-14
公開日2018-05-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s.
Nat Commun, 9, 2018
6V8O
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BU of 6v8o by Molmil
RSC core
分子名称: Chromatin structure-remodeling complex protein RSC14, Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, ...
著者Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E.
登録日2019-12-11
公開日2020-01-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
Elife, 8, 2019
6APQ
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BU of 6apq by Molmil
Anti-Marburgvirus Nucleoprotein Single Domain Antibody B
分子名称: Anti-Marburgvirus Nucleoprotein Single Domain Antibody B, CHLORIDE ION, SODIUM ION
著者Taylor, A.B, Garza, J.A.
登録日2017-08-17
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies.
Front Immunol, 8, 2017
6UYE
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BU of 6uye by Molmil
EBOV GPdMuc Makona bound to rEBOV-548 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ...
著者Murin, C.D, Ward, A.B.
登録日2019-11-13
公開日2020-03-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
1RF8
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BU of 1rf8 by Molmil
Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ...
著者Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G.
登録日2003-11-07
公開日2003-12-23
最終更新日2024-03-06
実験手法SOLUTION NMR
主引用文献Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell(Cambridge,Mass.), 115, 2003
6BU8
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BU of 6bu8 by Molmil
70S ribosome with S1 domains 1 and 2 (Class 1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
著者Loveland, A.B, Korostelev, A.A.
登録日2017-12-08
公開日2018-01-31
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM.
Methods, 137, 2018
6BIA
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BU of 6bia by Molmil
Crystal structure of Ps i-CgsB
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ...
著者Hettle, A.G, Boraston, A.B.
登録日2017-11-01
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme.
Structure, 26, 2018
6UQJ
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Crystal structure of the GH39 enzyme from Xanthomonas axonopodis pv. citri
分子名称: Beta-xylosidase
著者Morais, M.A.B, Polo, C.C, Santos, C.R, Murakami, M.T.
登録日2019-10-20
公開日2020-07-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 beta-Xylosidases.
Front Bioeng Biotechnol, 8, 2020

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