5YWR

Crystal Structure of RING E3 ligase ZNRF1 in complex with Ube2N (Ubc13)

Summary for 5YWR

Entry DOI	10.2210/pdb5ywr/pdb
Descriptor	Ubiquitin-conjugating enzyme E2 N, E3 ubiquitin-protein ligase ZNRF1, TRIETHYLENE GLYCOL, ... (6 entities in total)
Functional Keywords	ubiquitin e3 ligase, znrf1, ubiquitin conjugating e2, ube2n, ubc13, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	27574.73
Authors	Behera, A.P.,Naskar, P.,Datta, A.B. (deposition date: 2017-11-30, release date: 2018-06-06, Last modification date: 2024-03-27)
Primary citation	Behera, A.P.,Naskar, P.,Agarwal, S.,Banka, P.A.,Poddar, A.,Datta, A.B. Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications. Biochem. J., 475:1569-1582, 2018 Cited by PubMed: 29626159 DOI: 10.1042/BCJ20170909 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation