6U6Z
| |
1OIF
| Family 1 b-glucosidase from Thermotoga maritima | 分子名称: | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, BETA-GLUCOSIDASE | 著者 | Gloster, T, Zechel, D, Boraston, A.B, Boraston, C.M, Macdonald, J.M, Tilbrook, D.M, Stick, R.V, Davies, G.J. | 登録日 | 2003-06-16 | 公開日 | 2003-11-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases J.Am.Chem.Soc., 125, 2003
|
|
1OIM
| Family 1 b-glucosidase from Thermotoga maritima | 分子名称: | 1-DEOXYNOJIRIMYCIN, BETA-GLUCOSIDASE A | 著者 | Gloster, T, Zechel, D.L, Boraston, A.B, Boraston, C.M, Macdonald, J.M, Tilbrook, D.M, Stick, R.V, Davies, G.J. | 登録日 | 2003-06-19 | 公開日 | 2003-11-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases J.Am.Chem.Soc., 125, 2003
|
|
2QWL
| Crystal structure of bovine hsc70 (1-394aa)in the ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock cognate 71 kDa protein, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|
6UH0
| Human Carbonic Anhydrase 2 in complex with SB4-202 | 分子名称: | 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-09-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.306 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
1OW0
| Crystal structure of human FcaRI bound to IgA1-Fc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig alpha-1 chain C region, Immunoglobulin alpha Fc receptor, ... | 著者 | Herr, A.B, Ballister, E.R, Bjorkman, P.J. | 登録日 | 2003-03-27 | 公開日 | 2003-05-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc Nature, 423, 2003
|
|
1NOT
| THE 1.2 ANGSTROM STRUCTURE OF G1 ALPHA CONOTOXIN | 分子名称: | GI ALPHA CONOTOXIN | 著者 | Guddat, L.W, Shan, L, Martin, J.L, Edmundson, A.B, Gray, W.R. | 登録日 | 1996-05-02 | 公開日 | 1996-12-07 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Three-dimensional structure of the alpha-conotoxin GI at 1.2 A resolution Biochemistry, 35, 1996
|
|
1NWA
| Structure of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A in Complex with Protein-bound Methionine | 分子名称: | Peptide methionine sulfoxide reductase msrA | 著者 | Taylor, A.B, Benglis Jr, D.M, Dhandayuthapani, S, Hart, P.J, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-02-05 | 公開日 | 2003-07-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A in Complex with Protein-bound Methionine J.Bacteriol., 185, 2003
|
|
6U50
| Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
|
|
6U53
| |
6U6X
| Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide | 分子名称: | DNA SC-GS-SC-SC-DT, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | 登録日 | 2019-08-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
|
|
1OD0
| Family 1 b-glucosidase from Thermotoga maritima | 分子名称: | BETA-GLUCOSIDASE A | 著者 | Gloster, T, Zechel, D.L, Boraston, A.B, Boraston, C.M, Macdonald, J.M, Tilbrook, D.M, Stick, R.V, Davies, G.J. | 登録日 | 2003-02-12 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases J.Am.Chem.Soc., 125, 2003
|
|
2QWM
| Crystal structure of bovine hsc70 (1-394aa)in the ADP*Vi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock cognate 71 kDa protein, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|
6UGR
| Human Carbonic Anhydrase 2 complexed with SB4-208 | 分子名称: | 7-fluoro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-09-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.307 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
1O8P
| Unbound structure of CsCBM6-3 from Clostridium stercorarium | 分子名称: | CALCIUM ION, PUTATUVE ENDO-XYLANASE | 著者 | Boraston, A.B, Notenboom, V, Warren, R.A.J, Kilbrun, D.G, Rose, D.R, Davies, G.J. | 登録日 | 2002-11-28 | 公開日 | 2003-03-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains. J. Mol. Biol., 327, 2003
|
|
6U6Y
| Human SAMHD1 bound to ribo(CGCCU)-oligonucleotide | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA CGCCU, ... | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | 登録日 | 2019-08-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
|
|
6U4Q
| Carbonic anhydrase 2 in complex with SB4197 | 分子名称: | 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-08-26 | 公開日 | 2020-01-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.306 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
6U51
| Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 610-738 | 分子名称: | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB), Nucleoprotein | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
|
|
6U59
| HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ... | 著者 | Yang, Y.R, Ward, A.B. | 登録日 | 2019-08-27 | 公開日 | 2020-01-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits. J.Virol., 94, 2020
|
|
2QW9
| Crystal structure of bovine hsc70 (1-394aa)in the apo state | 分子名称: | GLYCEROL, Heat shock cognate 71 kDa protein | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|
6UFV
| |
6UGZ
| Human Carbonic Anhydrase IX-mimic complexed with SB4-208 | 分子名称: | 7-fluoro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase IX-mimic, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-09-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.306 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
6U55
| Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire E (ZE) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 634-738 | 分子名称: | Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire E (ZE), Nucleoprotein | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
|
|
6U52
| Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 634-738 | 分子名称: | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB), CHLORIDE ION, Nucleoprotein | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
|
|
2QWN
| Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-386aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|