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PDB: 89472 results

6XR3
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BU of 6xr3 by Molmil
X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A
Descriptor: 3C-like proteinase, N-[(2S)-1-({(1S,2S)-1-(1,3-benzothiazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Anson, B, Ghosh, A.K, Mesecar, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-07-10
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A
To Be Published
5GKE
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BU of 5gke by Molmil
Structure of EndoMS-dsDNA1 complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*CP*GP*CP*TP*AP*CP*AP*TP*GP*TP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*GP*AP*CP*GP*TP*GP*TP*AP*GP*CP*G)-3'), ...
Authors:Nakae, S, Hijikata, A, Tsuji, T, Yonezawa, K, Kouyama, K, Mayanagi, K, Ishino, S, Ishino, Y, Shirai, T.
Deposit date:2016-07-04
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease
Structure, 24, 2016
6ZEF
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BU of 6zef by Molmil
Structure of PP1(7-300) bound to Phactr1 (516-580) at pH 5.25
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M.
Deposit date:2020-06-16
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
4CDA
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BU of 4cda by Molmil
Spectroscopically-validated structure of ferric cytochrome c prime from Alcaligenes xylosoxidans
Descriptor: CYTOCHROME C', HEME C, SULFATE ION
Authors:Kekilli, D, Dworkowski, F, Antonyuk, S, Hough, M.A.
Deposit date:2013-10-30
Release date:2014-05-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Fingerprinting Redox and Ligand States in Haemprotein Crystal Structures Using Resonance Raman Spectroscopy.
Acta Crystallogr.,Sect.D, 70, 2014
5UL8
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BU of 5ul8 by Molmil
Apo KPC-2 beta-lactamase crystal structure at 1.15 Angstrom resolution
Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, SULFATE ION
Authors:Pemberton, O.A, Chen, Y.
Deposit date:2017-01-24
Release date:2017-04-26
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2).
J. Med. Chem., 60, 2017
4YC6
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BU of 4yc6 by Molmil
CDK1/CKS1
Descriptor: Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1
Authors:Brown, N.R, Korolchuk, S, Martin, M.P, Stanley, W, Moukhametzianov, R, Noble, M.E.M, Endicott, J.A.
Deposit date:2015-02-19
Release date:2015-05-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.
Nat Commun, 6, 2015
7T9B
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BU of 7t9b by Molmil
ApexGT5 in complex with GT5-d42.16 and RM20A3 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-18
Release date:2022-09-28
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens
Immunity, 2022
5A2I
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BU of 5a2i by Molmil
Crystal structure of scFv-SM3 in complex with APD-SGalNAc-RP
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ANTIGEN TN, ...
Authors:Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F.
Deposit date:2015-05-20
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody.
Angew.Chem.Int.Ed.Engl., 54, 2015
5LYZ
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BU of 5lyz by Molmil
Real-space refinement of the structure of hen egg-white lysozyme
Descriptor: HEN EGG WHITE LYSOZYME
Authors:Diamond, R, Phillips, D.C, Blake, C.C.F, North, A.C.T.
Deposit date:1975-02-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Real-space refinement of the structure of hen egg-white lysozyme.
J.Mol.Biol., 82, 1974
2ZTY
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BU of 2zty by Molmil
crystal structure of 3C protease from CVB3 in space group C2
Descriptor: 3C proteinase
Authors:Lee, C.C, Wang, A.H.-J.
Deposit date:2008-10-10
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
8E7E
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BU of 8e7e by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Afrin, S, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7J
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BU of 8e7j by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-24
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
1Q0V
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BU of 1q0v by Molmil
Solution Structure of Tandem UIMs of Vps27
Descriptor: hydrophilic protein; has cysteine rich putative zinc finger essential for function; Vps27p
Authors:Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L, Radhakrishnan, I.
Deposit date:2003-07-17
Release date:2003-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation.
Embo J., 22, 2003
8QX6
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BU of 8qx6 by Molmil
Novel laminarin-binding CBM X584
Descriptor: PKD domain-containing protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose
Authors:Zuehlke, M.K, Jeudy, A, Czjzek, M.
Deposit date:2023-10-22
Release date:2024-09-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unveiling the role of novel carbohydrate-binding modules in laminarin interaction of multimodular proteins from marine Bacteroidota during phytoplankton blooms.
Environ.Microbiol., 26, 2024
5M1K
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BU of 5m1k by Molmil
Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Magnesium
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Phage terminase large subunit, ...
Authors:Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
5M1P
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BU of 5m1p by Molmil
Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Calcium
Descriptor: CALCIUM ION, Terminase large subunit
Authors:Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
6PMP
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BU of 6pmp by Molmil
Crystal structure of a fragment of rat phospholipase Cepsilon EF3-RA1
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, CALCIUM ION
Authors:Rugema, N.Y, Lyon, A.M.
Deposit date:2019-07-02
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structure of phospholipase C epsilon reveals an integrated RA1 domain and previously unidentified regulatory elements.
Commun Biol, 3, 2020
5M22
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BU of 5m22 by Molmil
Crystal structure of hydroquinone 1,2-dioxygenase from Sphingomonas sp. TTNP3
Descriptor: FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit
Authors:Ferraroni, M, Da Vela, S, Scozzafava, A, Kolvenbach, B, Corvini, P.F.X.
Deposit date:2016-10-11
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structures of native hydroquinone 1,2-dioxygenase from Sphingomonas sp. TTNP3 and of substrate and inhibitor complexes.
Biochim. Biophys. Acta, 1865, 2017
7QZ8
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BU of 7qz8 by Molmil
Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
Descriptor: DAUNOMYCIN, Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H.
Deposit date:2022-01-30
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
7QZ7
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BU of 7qz7 by Molmil
Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp
Descriptor: DAUNOMYCIN, Transcriptional regulator, PadR-like family
Authors:Thunnissen, A.M.W.H.
Deposit date:2022-01-30
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
8G6J
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BU of 8g6j by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Descriptor: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-15
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G5Z
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BU of 8g5z by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
6XWL
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BU of 6xwl by Molmil
Cystathionine beta-synthase from Toxoplasma gondii
Descriptor: Cystathionine beta-synthase, PYRIDOXAL-5'-PHOSPHATE
Authors:Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A.
Deposit date:2020-01-23
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .
Comput Struct Biotechnol J, 19, 2021
6Z52
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BU of 6z52 by Molmil
Crystal structure of CLK3 in complex with macrocycle ODS2003136
Descriptor: 1,2-ETHANEDIOL, 11,15-dimethyl-6-(4-methylpiperazin-1-yl)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, CHLORIDE ION, ...
Authors:Chaikuad, A, Benderitter, P, Hoflack, J, Denis, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2020-05-26
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of CLK3 in complex with macrocycle ODS2003136
To Be Published
5TOD
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BU of 5tod by Molmil
Transmembrane protein 24 SMP domain
Descriptor: Transmembrane protein 24
Authors:Lees, J.A, Reinisch, K.M.
Deposit date:2016-10-17
Release date:2017-03-01
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion.
Science, 355, 2017

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数据于2024-10-16公开中

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