7ST2
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3X2G
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![BU of 3x2g by Molmil](/molmil-images/mine/3x2g) | X-ray structure of PcCel45A N92D apo form at 100K | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methylpentane-1,5-diol, Endoglucanase V-like protein | Authors: | Nakamura, A, Ishida, T, Samejima, M, Igarashi, K. | Deposit date: | 2014-12-22 | Release date: | 2015-10-07 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography. Sci Adv, 1, 2015
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7SSW
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3EOS
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![BU of 3eos by Molmil](/molmil-images/mine/3eos) | tRNA-guanine transglycosylase in complex with 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one | Descriptor: | 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | Authors: | Ritschel, T, Heine, A, Klebe, G. | Deposit date: | 2008-09-29 | Release date: | 2009-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase Chemmedchem, 4, 2009
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7SSD
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7SSN
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3EQ6
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![BU of 3eq6 by Molmil](/molmil-images/mine/3eq6) | Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a ternary complex with products | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-coenzyme A synthetase ACSM2A, Butyryl Coenzyme A | Authors: | Pilka, E.S, Kochan, G, Yue, W.W, Bhatia, C, Von delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2008-09-30 | Release date: | 2008-10-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A J.Mol.Biol., 388, 2009
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7SSL
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7SS9
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![BU of 7ss9 by Molmil](/molmil-images/mine/7ss9) | Late translocation intermediate with EF-G partially dissociated (Structure V) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A. | Deposit date: | 2021-11-10 | Release date: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
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2IZF
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![BU of 2izf by Molmil](/molmil-images/mine/2izf) | STREPTAVIDIN-BIOTIN PH 4.0 I222 COMPLEX | Descriptor: | BIOTIN, STREPTAVIDIN, SULFATE ION | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2ICY
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![BU of 2icy by Molmil](/molmil-images/mine/2icy) | Crystal Structure of a Putative UDP-glucose Pyrophosphorylase from Arabidopsis Thaliana with Bound UDP-glucose | Descriptor: | DIMETHYL SULFOXIDE, Probable UTP-glucose-1-phosphate uridylyltransferase 2, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... | Authors: | McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-09-13 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure and Dynamics of UDP-Glucose Pyrophosphorylase from Arabidopsis thaliana with Bound UDP-Glucose and UTP. J.Mol.Biol., 366, 2007
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1TK5
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![BU of 1tk5 by Molmil](/molmil-images/mine/1tk5) | T7 DNA polymerase binary complex with 8 oxo guanosine in the templating strand | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*A*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG)P*TP*GP*CP*AP*A)-3', ... | Authors: | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | Deposit date: | 2004-06-08 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
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6PPC
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![BU of 6ppc by Molmil](/molmil-images/mine/6ppc) | Solution structure of conotoxin MiXXVIIA | Descriptor: | Conopeptide phi-MiXXVIIA | Authors: | Daly, N.L, Dekan, Z, Jin, A.H, Alewood, P.F. | Deposit date: | 2019-07-06 | Release date: | 2019-08-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conotoxin phi-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity. Angew. Chem. Int. Ed. Engl., 56, 2017
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5K73
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![BU of 5k73 by Molmil](/molmil-images/mine/5k73) | as-isolated Dbr1 with Fe(II) and Zn(II) | Descriptor: | FE (II) ION, HYDROXIDE ION, RNA lariat debranching enzyme, ... | Authors: | Clark, N.E, Taylor, A.B, Hart, P.J. | Deposit date: | 2016-05-25 | Release date: | 2016-12-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The RNA lariat debranching enzyme Dbr1: metal dependence and branched RNA co-crystal structures Proc.Natl.Acad.Sci.USA, 2016
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1JT2
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![BU of 1jt2 by Molmil](/molmil-images/mine/1jt2) | STRUCTURAL BASIS FOR THE SUBSTRATE SPECIFICITY OF THE FERUL DOMAIN OF THE CELLULOSOMAL XYLANASE Z FROM C. THERMOCELLUM | Descriptor: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, PROTEIN (ENDO-1,4-BETA-XYLANASE Z) | Authors: | Schubot, F.D, Kataeva, I.A, Blum, D.L, Shah, A.K, Ljungdahl, L.G, Rose, J.P, Wang, B.-C. | Deposit date: | 2001-08-20 | Release date: | 2002-03-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the substrate specificity of the feruloyl esterase domain of the cellulosomal xylanase Z from Clostridium thermocellum. Biochemistry, 40, 2001
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3ZH3
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7ST7
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1SSB
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![BU of 1ssb by Molmil](/molmil-images/mine/1ssb) | A STRUCTURAL INVESTIGATION OF CATALYTICALLY MODIFIED F12OL AND F12OY SEMISYNTHETIC RIBONUCLEASES | Descriptor: | RIBONUCLEASE A, SULFATE ION | Authors: | Demel, V.S.J, Doscher, M.S, Glinn, M.A, Martin, P.D, Ram, M.L, Edwards, B.F.P. | Deposit date: | 1993-08-03 | Release date: | 1994-09-30 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases. Protein Sci., 3, 1994
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2W2I
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![BU of 2w2i by Molmil](/molmil-images/mine/2w2i) | Crystal structure of the human 2-oxoglutarate oxygenase LOC390245 | Descriptor: | 2-OXOGLUTARATE OXYGENASE, GLYCEROL, NICKEL (II) ION, ... | Authors: | Yue, W.W, Ng, S, Shafqat, N, Ugochukwu, E, McDonough, M, Pike, A.C.W, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C, Oppermann, U. | Deposit date: | 2008-10-31 | Release date: | 2009-01-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family. J.Biol.Chem., 286, 2011
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2IMQ
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![BU of 2imq by Molmil](/molmil-images/mine/2imq) | Crystal structure of ferrous cimex nitrophorin | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Salivary nitrophorin | Authors: | Weichsel, A, Montfort, W.R. | Deposit date: | 2006-10-04 | Release date: | 2007-08-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystallographic and spectroscopic characterization of ferrous complexes of cimex nitrophorin, a heme-thiolate protein from the bedbug To be Published
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1SWT
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![BU of 1swt by Molmil](/molmil-images/mine/1swt) | CORE-STREPTAVIDIN MUTANT D128A IN COMPLEX WITH BIOTIN AT PH 4.5 | Descriptor: | BIOTIN, PROTEIN (STREPTAVIDIN) | Authors: | Freitag, S, Le Trong, I, Chu, V, Klumb, L.A, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 1998-10-22 | Release date: | 1999-07-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway. Proc.Natl.Acad.Sci.USA, 96, 1999
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1SYS
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![BU of 1sys by Molmil](/molmil-images/mine/1sys) | Crystal structure of HLA, B*4403, and peptide EEPTVIKKY | Descriptor: | Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule | Authors: | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | Deposit date: | 2004-04-01 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion J.Exp.Med., 200, 2004
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4URY
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![BU of 4ury by Molmil](/molmil-images/mine/4ury) | The crystal structure of H-Ras and SOS in complex with ligands | Descriptor: | GTPASE HRAS, N-[(4-aminophenyl)sulfonyl]cyclopropanecarboxamide, SON OF SEVENLESS HOMOLOG 1 | Authors: | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | Deposit date: | 2014-07-02 | Release date: | 2015-03-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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1SZS
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![BU of 1szs by Molmil](/molmil-images/mine/1szs) | The structure of gamma-aminobutyrate aminotransferase mutant: I50Q | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ... | Authors: | Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Zhou, X, Fisher, A.J, Toney, M.D. | Deposit date: | 2004-04-06 | Release date: | 2005-03-01 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Biochemistry, 44, 2005
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6PMH
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![BU of 6pmh by Molmil](/molmil-images/mine/6pmh) | Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S. | Deposit date: | 2019-07-01 | Release date: | 2020-07-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus To Be Published
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