5CRH
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6VBC
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5X71
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8U8V
| Cryo-EM structure of Substrate ATP Bound in the Insertion Site (IS) of Human Mitochondrial Transcription Elongation Complex | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase, mitochondrial, ... | Authors: | Herbine, K.H, Nayak, A.R, Temiakov, D. | Deposit date: | 2023-09-18 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural basis for substrate binding and selection by human mitochondrial RNA polymerase. Nat Commun, 15, 2024
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6FCO
| Structural and functional characterisation of Frataxin (FXN) like protein from Chaetomium thermophilum | Descriptor: | MALONIC ACID, Mitochondrial frataxin-like protein | Authors: | Jamshidiha, M, Rasheed, M, Pastore, A, Cota, E. | Deposit date: | 2017-12-20 | Release date: | 2019-01-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural and functional characterization of a frataxin from a thermophilic organism. FEBS J., 286, 2019
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4YG8
| CRYSTAL STRUCTURE OF THE CHS5-CHS6 EXOMER CARGO ADAPTOR COMPLEX | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Chitin biosynthesis protein CHS5, Chitin biosynthesis protein CHS6, ... | Authors: | Paczkowski, J.E, Richardson, B.C, Strassner, A.M, Fromme, J.C. | Deposit date: | 2015-02-26 | Release date: | 2015-03-11 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The exomer cargo adaptor structure reveals a novel GTPase-binding domain. Embo J., 31, 2012
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5X7V
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7MA3
| HIV-1 Protease (I84V) in Complex with UMass2 | Descriptor: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}propyl]carbamate, Protease, SULFATE ION | Authors: | Lockbaum, G.J, Schiffer, C.A. | Deposit date: | 2021-03-31 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.969 Å) | Cite: | HIV-1 Protease (I84V) in Complex with UMass2 To Be Published
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5J8X
| CRYSTAL STRUCTURE OF E. COLI PBP5 WITH 2C | Descriptor: | (4~{R})-4-[[4-(aminomethyl)phenyl]carbonylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid, D-alanyl-D-alanine carboxypeptidase DacA | Authors: | Brem, J, Cain, R, McDonough, M.A, Clifton, I.J, Fishwick, C.W.G, Schofield, C.J. | Deposit date: | 2016-04-08 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structural basis of metallo-beta-lactamase, serine-beta-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nat Commun, 7, 2016
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6SCT
| Cryo-EM structure of the consensus triskelion hub of the clathrin coat complex | Descriptor: | Clathrin heavy chain, Clathrin light chain | Authors: | Morris, K.L, Cameron, A.D, Sessions, R, Smith, C.J. | Deposit date: | 2019-07-25 | Release date: | 2019-10-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.69 Å) | Cite: | Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly. Nat.Struct.Mol.Biol., 26, 2019
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5JJ5
| Crystal structure of iron uptake ABC transporter substrate-binding protein PiaA from Streptococcus pneumoniae Canada MDR_19A bound to hydroxymate siderophore ferrioxamine E and iron(III) | Descriptor: | (8E)-6,17,28-trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacont-8-ene-2,5,13,16,24,27-hexone, ABC transporter substrate-binding protein-iron transport, CHLORIDE ION, ... | Authors: | Stogios, P.J, Wawrzak, Z, Kurdritska, M, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-04-22 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of iron uptake ABC transporter substrate-binding protein PiaA from Streptococcus pneumoniae Canada MDR_19A bound to hydroxymate siderophore ferrioxamine E and iron(III) To Be Published
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8U8U
| Cryo-EM Structure of Cognate Substrate ATP Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase, mitochondrial, ... | Authors: | Herbine, K.H, Nayak, A.R, Temiakov, D. | Deposit date: | 2023-09-18 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for substrate binding and selection by human mitochondrial RNA polymerase. Nat Commun, 15, 2024
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6F05
| ARABIDOPSIS THALIANA GSTF9, GSO3 BOUND | Descriptor: | CHLORIDE ION, GLUTATHIONE SULFONIC ACID, GLYCEROL, ... | Authors: | Tossounian, M.A, Wahni, K, VanMolle, I, Vertommen, D, Rosado, L, Messens, J. | Deposit date: | 2017-11-17 | Release date: | 2018-08-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility. Protein Sci., 28, 2019
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5JK0
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5H4H
| Structure of PIN-domain protein (VapC4 toxin) from Pyrococcus horikoshii determined at 2.2 A resolution | Descriptor: | CADMIUM ION, Ribonuclease VapC4 | Authors: | Biswas, A, Hatti, K, Srinivasan, N, Murthy, M.R.N, Sekar, K. | Deposit date: | 2016-10-31 | Release date: | 2016-11-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structure determination of contaminant proteins using the MarathonMR procedure J. Struct. Biol., 197, 2017
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6XF8
| DLP 5 fold | Descriptor: | Inner capsid protein lambda-1, Inner capsid protein sigma-2, Outer capsid protein mu-1, ... | Authors: | Sutton, G, Sun, D.P, Fu, X.F, Kotecha, A, Hecksel, G.W, Clare, D.K, Zhang, P, Stuart, D, Boyce, M. | Deposit date: | 2020-06-15 | Release date: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Assembly intermediates of orthoreovirus captured in the cell. Nat Commun, 11, 2020
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6SFI
| Crystal structure of p38 alpha in complex with compound 75 (MCP33) | Descriptor: | Mitogen-activated protein kinase 14, ~{N}-[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]-2-[[[1-(2-methylphenyl)pyrazol-4-yl]carbonylamino]methyl]-1,3-thiazole-5-carboxamide | Authors: | Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2019-08-01 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors. J.Med.Chem., 62, 2019
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6S8X
| Crystal structure of the Rab-binding domain of FIP2 | Descriptor: | HEXANE-1,6-DIOL, Rab11 family-interacting protein 2 | Authors: | Kearney, A.M, Khan, A.R. | Deposit date: | 2019-07-10 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of the Rab-binding domain of Rab11 family-interacting protein 2. Acta Crystallogr.,Sect.F, 76, 2020
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6F53
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6EVO
| Crystal structure the peptide-substrate-binding domain of human type II collagen prolyl 4-hydroxylase complexed with Pro-Pro-Gly-Pro-Arg-Gly-Pro-Pro-Gly. | Descriptor: | DIMETHYL SULFOXIDE, PRO-PRO-GLY-PRO-ARG-GLY-PRO-PRO-GLY, Prolyl 4-hydroxylase subunit alpha-2, ... | Authors: | Murthy, A.V, Sulu, R, Koski, M.K, Wierenga, R.K. | Deposit date: | 2017-11-02 | Release date: | 2018-09-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif. Protein Sci., 27, 2018
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6B21
| Crystal structure of AmtB from E. coli bound to TopFluor cardiolipin | Descriptor: | Ammonia channel, [(2R,5R,11R,14S,24E)-14-[(acetyloxy)methyl]-8-{[5-(3,5-dimethyl-1H-pyrrol-2-yl-kappaN)-5-(3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)pentanoyl]oxy}-5,11-dihydroxy-2-{[(9E)-octadec-9-enoyl]oxy}-5,11,16-trioxo-4,6,10,12,15-pentaoxa-5lambda~5~,11lambda~5~-diphosphatritriacont-24-en-1-yl (9E)-octadec-9-enoatato](difluoro)boron | Authors: | Boone, C.D, Laganowsky, A. | Deposit date: | 2017-09-19 | Release date: | 2018-03-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Allostery revealed within lipid binding events to membrane proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1NBS
| Crystal structure of the specificity domain of Ribonuclease P RNA | Descriptor: | LEAD (II) ION, MAGNESIUM ION, RIBONUCLEASE P RNA | Authors: | Krasilnikov, A.S, Yang, X, Pan, T, Mondragon, A. | Deposit date: | 2002-12-03 | Release date: | 2003-02-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal structure of the specificity domain of Ribonuclease P Nature, 421, 2003
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5A7R
| Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ... | Authors: | Lambrecht, M.J, Brichacek, M, Barkauskaite, E, Ariza, A, Ahel, I, Hergenrother, P.J. | Deposit date: | 2015-07-09 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Synthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase. J.Am.Chem.Soc., 137, 2015
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6B2V
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6PEI
| Structure of sorbitol dehydrogenase from Sinorhizobium meliloti 1021 | Descriptor: | Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) | Authors: | Bailey-Elkin, B.A, Kohlmeier, M.G, Oresnik, I.J, Mark, B.L. | Deposit date: | 2019-06-20 | Release date: | 2020-06-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Characterization of the sorbitol dehydrogenase SmoS from Sinorhizobium meliloti 1021 Acta Crystallogr.,Sect.D, 77, 2021
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