8U8U

Cryo-EM Structure of Cognate Substrate ATP Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex

Summary for 8U8U

Entry DOI	10.2210/pdb8u8u/pdb
EMDB information	42027
Descriptor	Transcription elongation factor, mitochondrial, DNA-directed RNA polymerase, mitochondrial, Non-Template Strand DNA (NT27mt), ... (6 entities in total)
Functional Keywords	mitochondrial rna polymerase, nucleotide selection, nucleotide discrimination, transcription, protein-rna-dna complex, polrmt, transcription-dna-rna complex, transcription/dna/rna
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	207577.21
Authors	Herbine, K.H.,Nayak, A.R.,Temiakov, D. (deposition date: 2023-09-18, release date: 2024-09-04)
Primary citation	Herbine, K.,Nayak, A.R.,Temiakov, D. Structural basis for substrate binding and selection by human mitochondrial RNA polymerase. Nat Commun, 15:7134-7134, 2024 Cited by PubMed: 39164235 DOI: 10.1038/s41467-024-50817-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation