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PDB: 89111 件

8D7O
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Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7P
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Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide
分子名称: Casein kinase I isoform delta, Period circadian protein peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
4XFM
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Crystal structure of a domain of unknown function (DUF1537) from Pectobacterium atrosepticum (ECA3761), Target EFI-511609, with bound D-threonate, domain swapped dimer
分子名称: THREONATE ION, Uncharacterized protein
著者Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-12-27
公開日2015-04-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.
Proc.Natl.Acad.Sci.USA, 113, 2016
4XI1
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Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase LubX, GLYCEROL, ...
著者Stogios, P.J, Quaile, T, Skarina, T, Cuff, M, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-01-06
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.983 Å)
主引用文献Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
8DHL
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Tannerella forsythia beta-glucuronidase (L2)
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 2, ...
著者Lietzan, A.D, Redinbo, M.R.
登録日2022-06-27
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Microbial beta-glucuronidases drive human periodontal disease etiology.
Sci Adv, 9, 2023
7LRB
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BU of 7lrb by Molmil
Ni-bound crystal structure of the engineered cyt cb562 variant, DiCyt2, crystallized in the presence of Ni(II) (M1) and Cu(II) (M2)
分子名称: COBALT (II) ION, HEME C, Soluble cytochrome b562
著者Choi, T.S, Tezcan, F.A.
登録日2021-02-16
公開日2022-02-23
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Overcoming universal restrictions on metal selectivity by protein design.
Nature, 603, 2022
8DHV
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Treponema lecithinolyticum beta-glucuronidase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Glycosyl hydrolase family 2, ...
著者Lietzan, A.D, Redinbo, M.R.
登録日2022-06-28
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Microbial beta-glucuronidases drive human periodontal disease etiology.
Sci Adv, 9, 2023
4QQY
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Crystal structure of T. fusca Cas3-ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
著者Ke, A, Huo, Y, Nam, K.H.
登録日2014-06-30
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
6DWY
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Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+
分子名称: CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ...
著者Dyda, F, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
8T67
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Influenza PA-N Endonuclease I38T Mutant (amino acids 52-74 truncation)
分子名称: MANGANESE (II) ION, Polymerase acidic protein
著者Kohlbrand, A.J, Cohen, S.M.
登録日2023-06-15
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants.
Biochemistry, 63, 2024
6UIH
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Crystal structure of the core domain from the GST-like protein GDAP1
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Googins, M.R, VanDemark, A.P.
登録日2019-09-30
公開日2020-04-29
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (2.826 Å)
主引用文献Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily.
Faseb J., 34, 2020
7TNK
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Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
5G10
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Pseudomonas aeruginosa HDAH bound to 9,9,9 trifluoro-8,8-dihydroy-N-phenylnonanamide
分子名称: 9,9,9-tris(fluoranyl)-8,8-bis(oxidanyl)-~{N}-phenyl-nonanamide, HDAH, POTASSIUM ION, ...
著者Kraemer, A, Meyer-Almes, F.J, Yildiz, O.
登録日2016-03-23
公開日2016-11-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal Structure of a Histone Deacetylase Homologue from Pseudomonas aeruginosa.
Biochemistry, 55, 2016
5ZW7
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FAD-PigA complex at 1.3 A
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Lee, C.-C, Ko, T.-P, Wang, A.H.J.
登録日2018-05-14
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis.
Chembiochem, 20, 2019
7LV1
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BU of 7lv1 by Molmil
Cu-bound crystal structure of the engineered cyt cb562 variant, DiCyt2, crystallized in the presence of Cu(II)
分子名称: CALCIUM ION, COPPER (II) ION, HEME C, ...
著者Choi, T.S, Tezcan, F.A.
登録日2021-02-23
公開日2022-03-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Overcoming universal restrictions on metal selectivity by protein design.
Nature, 603, 2022
7TNO
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Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
5KB1
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Crystal Structure of a Tris-thiolate Hg(II) Complex in a de Novo Three Stranded Coiled Coil Peptide
分子名称: CHLORIDE ION, Hg(II)Zn(II)(GRAND Coil Ser-L16CL30H)3+, MERCURY (II) ION, ...
著者Ruckcthong, L, Zastrow, M.L, Stuckey, J.A, Pecoraro, V.L.
登録日2016-06-02
公開日2016-08-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins.
J.Am.Chem.Soc., 138, 2016
7TNM
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BU of 7tnm by Molmil
Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
8A8J
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BU of 8a8j by Molmil
Complex of RecF and DNA from Thermus thermophilus.
分子名称: DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ...
著者Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M.
登録日2022-06-23
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
6AF6
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BU of 6af6 by Molmil
PigA with FAD and proline
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Lee, C.-C, Ko, T.-P, Wang, A.H.J.
登録日2018-08-08
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis.
Chembiochem, 20, 2019
6HQ0
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Crystal structure of ENL (MLLT1), apo form
分子名称: 1,2-ETHANEDIOL, Protein ENL
著者Heidenreich, D, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2018-09-22
公開日2018-11-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).
J.Med.Chem., 61, 2018
4XN4
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BU of 4xn4 by Molmil
Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine
分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
著者Addlagatta, A, Gumpena, R.
登録日2015-01-15
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine
To Be Published
6TZA
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CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant
分子名称: IST1 homolog
著者Nguyen, H.C, Frost, A.
登録日2019-08-11
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
8POD
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BU of 8pod by Molmil
Crystal structure of the kinase domain of ACVR1 (ALK2) in complex with FKBP12 and MU1700
分子名称: 6-(4-piperazin-1-ylphenyl)-3-quinolin-4-yl-furo[3,2-b]pyridine, Activin receptor type-1, FLUORIDE ION, ...
著者Cros, J, Baltanas-Copado, J, Knapp, S, Paruch, K, Nemec, N, Bullock, A.N.
登録日2023-07-04
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structure of the kinase domain of ACVR1 (ALK2) in complex with FKBP12 and MU1700
To Be Published
4XLQ
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Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter
分子名称: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015

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件を2024-09-11に公開中

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