8POD

Crystal structure of the kinase domain of ACVR1 (ALK2) in complex with FKBP12 and MU1700

Summary for 8POD

• Entry DOI: 10.2210/pdb8pod/pdb
• Descriptor: Activin receptor type-1, Peptidyl-prolyl cis-trans isomerase FKBP1A, 6-(4-piperazin-1-ylphenyl)-3-quinolin-4-yl-furo[3,2-b]pyridine, ... (5 entities in total)
• Functional Keywords: alk2, fkbp12, acvr1, kinase, complex, inhibitor, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 49879.00

Authors

Cros, J.,Baltanas-Copado, J.,Knapp, S.,Paruch, K.,Nemec, N.,Bullock, A.N. (deposition date: 2023-07-04, release date: 2024-06-19)

• Primary citation: Cros, J.,Baltanas-Copado, J.,Bullock, A.N.; Crystal structure of the kinase domain of ACVR1 (ALK2) in complex with FKBP12 and MU1700; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.59 Å)