4XFM

Crystal structure of a domain of unknown function (DUF1537) from Pectobacterium atrosepticum (ECA3761), Target EFI-511609, with bound D-threonate, domain swapped dimer

Summary for 4XFM

• Entry DOI: 10.2210/pdb4xfm/pdb
• Descriptor: Uncharacterized protein, THREONATE ION (3 entities in total)
• Functional Keywords: enzyme function initiative, efi, structural genomics, unknown function
• Biological source: Pectobacterium atrosepticum
• Total number of polymer chains: 1
• Total formula weight: 49413.58

Authors

Vetting, M.W.,Al Obaidi, N.F.,Toro, R.,Morisco, L.L.,Benach, J.,Wasserman, S.R.,Attonito, J.D.,Scott Glenn, A.,Chamala, S.,Chowdhury, S.,Lafleur, J.,Love, J.,Seidel, R.D.,Whalen, K.L.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2014-12-27, release date: 2015-04-01, Last modification date: 2023-09-27)

• Primary citation: Zhang, X.,Carter, M.S.,Vetting, M.W.,San Francisco, B.,Zhao, S.,Al-Obaidi, N.F.,Solbiati, J.O.,Thiaville, J.J.,de Crecy-Lagard, V.,Jacobson, M.P.,Almo, S.C.,Gerlt, J.A.; Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.; Proc.Natl.Acad.Sci.USA, 113:E4161-E4169, 2016; PubMed: 27402745; DOI: 10.1073/pnas.1605546113

Experimental method

X-RAY DIFFRACTION (1.55 Å)