7ZUF
| Saccharomyces cerevisiae L-BC virus, open particle, C5 reconstruction | 分子名称: | Major capsid protein | 著者 | Grybchuk, D, Prochazkova, M, Fuzik, T, Konovalovas, A, Serva, S, Yurchenko, V, Plevka, P. | 登録日 | 2022-05-12 | 公開日 | 2022-09-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly. Commun Biol, 5, 2022
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4QJA
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5F5V
| Crystal structure of the Snu23-Prp38-MFAP1(217-296) complex of Chaetomium thermophilum | 分子名称: | Prp38, Putative uncharacterized protein, Zinc finger domain-containing protein | 著者 | Ulrich, A.K.C, Seeger, M, Bartlick, N, Wahl, M.C. | 登録日 | 2015-12-04 | 公開日 | 2016-10-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Scaffolding in the Spliceosome via Single alpha Helices. Structure, 24, 2016
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5IQH
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5IRF
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8CB5
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6DRR
| Crystal structure of Cj0485 dehydrogenase | 分子名称: | 1,2-ETHANEDIOL, Short-chain dehydrogenase | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2018-06-12 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus. Commun Biol, 3, 2020
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7LP2
| Structure of Nedd4L WW3 domain | 分子名称: | Angiomotin, E3 ubiquitin-protein ligase, GLYCEROL, ... | 著者 | Alian, A, Alam, S.L, Thompson, T, Rheinemann, L, Sundquist, W.I. | 登録日 | 2021-02-11 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release. J.Biol.Chem., 297, 2021
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6DND
| Crystal structure of wild-type (WT) human Glutamate oxaloacetate transaminase 1 (GOT1) | 分子名称: | Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | 登録日 | 2018-06-06 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry, 57, 2018
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7LP3
| Structure of Nedd4L WW3 domain | 分子名称: | Angiomotin, E3 ubiquitin-protein ligase NEDD4-like, SULFATE ION | 著者 | Alian, A, Alam, S.L, Thompson, T, Rheinemann, L, Sundquist, W.I. | 登録日 | 2021-02-11 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release. J.Biol.Chem., 297, 2021
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7ZMD
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5EZE
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6QU2
| Crystal structure of DYRK1A complexed with FC162 inhibitor | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-cyclopropyl-2-pyridin-3-yl-[1,3]thiazolo[5,4-f]quinazolin-9-one, DIMETHYL SULFOXIDE, ... | 著者 | Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Besson, T, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2019-02-26 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of DYRK1A complexed with FC162 inhibitor To Be Published
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7ZMC
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7ZMA
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8TBT
| Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator Compound 2 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, MANGANESE (II) ION, POTASSIUM ION, ... | 著者 | Jin, L, Padyana, A. | 登録日 | 2023-06-29 | 公開日 | 2023-12-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structure-Based Design of AG-946, a Pyruvate Kinase Activator. Chemmedchem, 19, 2024
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6QNA
| Structure of bovine anti-RSV hybrid Fab B13HC-B4LC | 分子名称: | B13 Heavy chain, B4 light chain, GLYCEROL | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | 登録日 | 2019-02-10 | 公開日 | 2019-05-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus. Mol.Immunol., 112, 2019
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6QV9
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4QOJ
| CRYSTAL STRUCTURE OF FMN QUINONE REDUCTASE 2 IN COMPLEX WITH RESVERATROL AT 1.85A | 分子名称: | FLAVIN MONONUCLEOTIDE, RESVERATROL, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Serriere, J, Boutin, J.A, Isabet, T, Antoine, M, Ferry, G. | 登録日 | 2014-06-20 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | CRYSTAL STRUCTURE OF FMN QUINONE REDUCTASE 2 IN COMPLEX WITH RESVERATROL AT 1.85A To be Published
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5F0A
| CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine INHIBITOR | 分子名称: | 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, cGMP-dependent protein kinase, putative | 著者 | Walker, J.R, Wernimont, A.K, He, H, Seitova, A, Loppnau, P, Sibley, L.D, Graslund, S, Hutchinson, A, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Hui, R, El Bakkouri, M, Structural Genomics Consortium (SGC) | 登録日 | 2015-11-27 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND INHIBITOR To be published
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7QGY
| Human carbonic anhydrase II in complex with 3-((5-(ethoxycarbonyl)-4-methylthiazol-2-yl)(4-sulfamoylphenyl)amino)propanoic acid | 分子名称: | 3-[(5-ethoxycarbonyl-4-methyl-1,3-thiazol-2-yl)-(4-sulfamoylphenyl)amino]propanoic acid, Carbonic anhydrase 2, ZINC ION | 著者 | Paketuryte-Latve, V, Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2021-12-10 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Beta and Gamma Amino Acid-Substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases. Pharmaceuticals, 15, 2022
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6DRY
| Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (8beta)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-9,10-didehydroergoline-8-carboxamide, 5HT2B receptor, ... | 著者 | McCorvy, J.D, Wacker, D, Wang, S, Agegnehu, B, Liu, J, Lansu, K, Tribo, A.R, Olsen, R.H.J, Che, T, Jin, J, Roth, B.L. | 登録日 | 2018-06-13 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.918 Å) | 主引用文献 | Structural determinants of 5-HT2Breceptor activation and biased agonism. Nat. Struct. Mol. Biol., 25, 2018
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6DS1
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6QMV
| E87D sulfur oxygenase reductase | 分子名称: | Sulfur oxygenase/reductase | 著者 | Frazao, C, Klezin, A, Veith, A. | 登録日 | 2019-02-08 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Multiple sulfane modifications in active-site cysteine thiols of two sulfur oxygenase reductases and analysis of substrate/product channels To Be Published
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5IQD
| Aminoglycoside Phosphotransferase (2'')-Ia (CTD of AAC(6')-Ie/APH(2'')-Ia) in complex with GMPPNP, Magnesium, and Ribostamycin | 分子名称: | Bifunctional AAC/APH, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Caldwell, S.J, Berghuis, A.M. | 登録日 | 2016-03-10 | 公開日 | 2016-05-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia. Structure, 24, 2016
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